Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release. (Q33760871)

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English	Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release.	scientific article

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9 March 2020

Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release (English)

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9 March 2020

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9 March 2020

Matteo Iannacone

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Omid C. Farokhzad

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Robert S. Langer, Jr.

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Robert S Langer

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Aleksandar F Radovic-Moreno

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Aleksandar F Radovic-Moreno

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Jinjun Shi

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Petr O Ilyinskii

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Conlin P O'Neil

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Erica A Browning

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Lynnelle A Pittet

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David H Altreuter

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Frank Alexis

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Lloyd P M Johnston

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9 March 2020

Takashi Kei Kishimoto

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9 March 2020

Ulrich H von Andrian

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1 March 2014

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2882-2895

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9 March 2020

Adjuvants for human vaccines

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Innate immunity and adjuvants

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Immunological mechanisms of vaccination

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Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns

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Unmet needs in modern vaccinology: adjuvants to improve the immune response

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Immunostimulatory CpG oligonucleotides: Effect on gene expression and utility as vaccine adjuvants

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CpG oligodeoxynucleotides as TLR9 agonists: therapeutic applications in cancer.

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Paradoxical enhancement of CD8 T cell-dependent anti-tumor protection despite reduced CD8 T cell responses with addition of a TLR9 agonist to a tumor vaccine

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The Toll-like receptor 7 (TLR7) agonist, imiquimod, and the TLR9 agonist, CpG ODN, induce antiviral cytokines and chemokines but do not prevent vaginal transmission of simian immunodeficiency virus when applied intravaginally to rhesus macaques

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Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

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Intratumor CpG-Oligodeoxynucleotide Injection Induces Protective Antitumor T Cell Immunity

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30 October 2018

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Phase II trial of a toll-like receptor 9-activating oligonucleotide in patients with metastatic melanoma

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