Senescent fibroblasts promote neoplastic transformation of partially transformed ovarian epithelial cells in a three-dimensional model of early stage ovarian cancer (Q33762391)

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English	Senescent fibroblasts promote neoplastic transformation of partially transformed ovarian epithelial cells in a three-dimensional model of early stage ovarian cancer	scientific article

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scholarly article

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Europe PubMed Central

29 July 2017

Senescent fibroblasts promote neoplastic transformation of partially transformed ovarian epithelial cells in a three-dimensional model of early stage ovarian cancer (English)

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Europe PubMed Central

29 July 2017

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based on heuristic

inferred from title

Simon A Gayther

6

object named as

Simon A Gayther

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Europe PubMed Central

29 July 2017

author name string

Kate Lawrenson

1

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Europe PubMed Central

29 July 2017

Barbara Grun

2

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Europe PubMed Central

29 July 2017

Elizabeth Benjamin

3

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Europe PubMed Central

29 July 2017

Ian J Jacobs

4

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Europe PubMed Central

29 July 2017

Dimitra Dafou

5

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Europe PubMed Central

29 July 2017

publication date

1 April 2010

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Europe PubMed Central

29 July 2017

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Europe PubMed Central

29 July 2017

12

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Europe PubMed Central

29 July 2017

4

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Europe PubMed Central

29 July 2017

317-325

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Europe PubMed Central

29 July 2017

describes a project that uses

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Senescent stromal-derived osteopontin promotes preneoplastic cell growth

1 reference

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Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

1 reference

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22 June 2018

Ovarian ageing, follicle depletion, and cancer: a hypothesis for the aetiology of epithelial ovarian cancer involving follicle depletion

1 reference

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22 June 2018

Fibroblasts isolated from common sites of breast cancer metastasis enhance cancer cell growth rates and invasiveness in an interleukin-6-dependent manner.

1 reference

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22 June 2018

p16INK4a downregulation is involved in immortalization of primary human prostate epithelial cells induced by telomerase

1 reference

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22 June 2018

Human ovarian surface epithelial cells immortalized with hTERT maintain functional pRb and p53 expression.

1 reference

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22 June 2018

Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion

1 reference

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22 June 2018

Accumulation of senescent cells in mitotic tissue of aging primates

1 reference

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22 June 2018

The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis

1 reference

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22 June 2018

Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence

1 reference

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22 June 2018

Methylation of the p16(INK4a) promoter region in telomerase immortalized human keratinocytes co-cultured with feeder cells

1 reference

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22 June 2018

Age-dependent morphological alterations of human ovaries from populations with and without BRCA mutations

1 reference

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22 June 2018

Immunohistochemical detection of human telomerase reverse transcriptase (hTERT) and c-kit in serous ovarian carcinoma: a clinicopathologic study

1 reference

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22 June 2018

Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847739

22 June 2018

Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847739

22 June 2018

Ovulation and risk of epithelial ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847739

22 June 2018

Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847739

22 June 2018

Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847739

22 June 2018

The transcriptional program in the response of human fibroblasts to serum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847739

22 June 2018

Response of a primary human fibroblast cell line to H2O2: senescence-like growth arrest or apoptosis?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847739

22 June 2018

Ovarian cancer. Age contrasts in incidence, histology, disease stage at diagnosis, and mortality.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847739

22 June 2018

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

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22 June 2018

Incessant ovulation--a factor in ovarian neoplasia?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847739

22 June 2018

In vitro three-dimensional modelling of human ovarian surface epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847739

30 October 2018

Cellular senescence in aging primates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847739

30 October 2018

The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847739

30 October 2018

CXCL12 overexpression and secretion by aging fibroblasts enhance human prostate epithelial proliferation in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847739

30 October 2018

Hormonal factors and the risk of invasive ovarian cancer: a population-based case-control study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847739

30 October 2018

Prolonged culture of telomerase-immortalized human fibroblasts leads to a premalignant phenotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847739

30 October 2018

p16(INK4a) inactivation is not required to immortalize human mammary epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847739

30 October 2018

The postmenopausal ovary is not a major androgen-producing gland

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847739

30 October 2018

Correlations between c-myc gene copy-number and clinicopathological parameters of ovarian tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847739

30 October 2018

Identifiers

10.1593/NEO.91948

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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