Antioxidant functions of sulforaphane: a potent inducer of Phase II detoxication enzymes (Q33763068)

29 July 2017

1 reference

title

Antioxidant functions of sulforaphane: a potent inducer of Phase II detoxication enzymes (English)

1 reference

29 July 2017

J W Fahey

1

1 reference

PubMed ID

10541453

29 July 2017

P Talalay

series ordinal

2

1 reference

29 July 2017

1 September 1999

1 reference

Food and Chemical Toxicology

29 July 2017

1 reference

29 July 2017

37

1 reference

29 July 2017

973-979

1 reference

29 July 2017

9-10

1 reference

Glutathione transferases catalyse the detoxication of oxidized metabolites (o-quinones) of catecholamines and may serve as an antioxidant system preventing degenerative cellular processes

29 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

The role of DT-diaphorase in the maintenance of the reduced antioxidant form of coenzyme Q in membrane systems

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Structure-activity relationships of 4-hydroxyalkenals in the conjugation catalysed by mammalian glutathione transferases

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Relation of structure of curcumin analogs to their potencies as inducers of Phase 2 detoxification enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Activation of endogenous antioxidant defenses in neuronal cells prevents free radical-mediated damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Selective increase of the potential anticarcinogen 4-methylsulphinylbutyl glucosinolate in broccoli

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Glucosinolates and their breakdown products in food and food plants

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Selective cytostatic and cytotoxic effects of glucosinolates hydrolysis products on human colon cancer cells in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Raphanin, an antibacterial principle of the radish (Raphanus sativus).

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Biotransformation of the naturally occurring isothiocyanate sulforaphane in the rat: identification of phase I metabolites and glutathione conjugates

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Isothiocyanates as substrates for human glutathione transferases: structure-activity studies.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Overexpression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

The use of primary hepatocyte cultures for the evaluation of chemoprotective agents

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Constitutive and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Enhanced NAD(P)H:Quinone Reductase Activity Prevents Glutamate Toxicity Produced by Oxidative Stress

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: correlation between structure and potency as inducers of anticarcinogenic detoxication enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE)

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

The electrophile counterattack response: protection against neoplasia and toxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Rapid detection of inducers of enzymes that protect against carcinogens

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Isolation of sulforaphane from hoary cress (Lepidium draba L.)

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Disruption of the DT diaphorase (NQO1) gene in mice leads to increased menadione toxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

1 reference

7 January 2021

An unusual case of 'uncompetitive activation' by ascorbic acid: purification and kinetic properties of a myrosinase from Raphanus sativus seedlings

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

The reduction of alpha-tocopherolquinone by human NAD(P)H: quinone oxidoreductase: the role of alpha-tocopherolhydroquinone as a cellular antioxidant

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

The potency of inducers of NAD(P)H:(quinone-acceptor) oxidoreductase parallels their efficiency as substrates for glutathione transferases. Structural and electronic correlations

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Antioxidant activity of albumin-bound bilirubin

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Chemoprotection against cancer by isothiocyanates and glucosinolates.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Reversible conjugation of isothiocyanates with glutathione catalyzed by human glutathione transferases

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates

1 reference

https://api.crossref.org/works/10.1016%2FS0278-6915%2899%2900082-4

7 January 2021

10.1016/S0278-6915(99)00082-4

Identifiers

DOI

1 reference

29 July 2017

1 reference

PubMed ID

10541453