Purification, potency, and efficacy of the botulinum neurotoxin type A binding domain from Pichia pastoris as a recombinant vaccine candidate. (Q33765582)

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English	Purification, potency, and efficacy of the botulinum neurotoxin type A binding domain from Pichia pastoris as a recombinant vaccine candidate.	scientific article

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scholarly article

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4 December 2019

Purification, potency, and efficacy of the botulinum neurotoxin type A binding domain from Pichia pastoris as a recombinant vaccine candidate (English)

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4 December 2019

Pichia pastoris

object named as

Pichia pastoris

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M P Byrne

1

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4 December 2019

T J Smith

2

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4 December 2019

V A Montgomery

3

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L A Smith

4

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1 October 1998

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4 December 2019

Infection and Immunity

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4 December 2019

66

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10

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4 December 2019

4817-4822

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4 December 2019

PREPARATION AND ASSAY OF THE INTERNATIONAL STANDARDS FOR CLOSTRIDIUM BOTULINUM TYPES A, B, C, D AND E ANTITOXINS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108595

22 June 2018

Expression of a large, nontoxic fragment of botulinum neurotoxin serotype A and its use as an immunogen

1 reference

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22 June 2018

Identification of the nerve terminal targets of botulinum neurotoxin serotypes A, D, and E

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108595

22 June 2018

Identification of protein receptor for Clostridium botulinum type B neurotoxin in rat brain synaptosomes.

1 reference

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22 June 2018

Protective vaccination with a recombinant fragment of Clostridium botulinum neurotoxin serotype A expressed from a synthetic gene in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108595

22 June 2018

Recent advances in the expression of foreign genes in Pichia pastoris

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108595

22 June 2018

Structure and function of Clostridium botulinum toxins

1 reference

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22 June 2018

Pichia pastoris as a host system for transformations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108595

22 June 2018

Inactivation of Clostridium botulinum type A neurotoxin by trypsin and purification of two tryptic fragments. Proteolytic action near the COOH-terminus of the heavy subunit destroys toxin-binding activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108595

22 June 2018

Interaction of 125I-labeled botulinum neurotoxins with nerve terminals. I. Ultrastructural autoradiographic localization and quantitation of distinct membrane acceptors for types A and B on motor nerves

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108595

22 June 2018

Clostridial neurotoxins: handling and action at the cellular and molecular level

1 reference

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22 June 2018

Molecular pharmacology of botulinum toxin and tetanus toxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108595

22 June 2018

Immunization of mice against tetanus with fragments of tetanus toxin synthesized in Escherichia coli

1 reference

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22 June 2018

Human immune response to botulinum pentavalent (ABCDE) toxoid determined by a neutralization test and by an enzyme-linked immunosorbent assay.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108595

22 June 2018

A 50-kDa fragment from the NH2-terminus of the heavy subunit of Clostridium botulinum type A neurotoxin forms channels in lipid vesicles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108595

22 June 2018

Foreign gene expression in yeast: a review

1 reference

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22 June 2018

Tetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zinc

1 reference

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22 June 2018

Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108595

22 June 2018

High level expression of heterologous proteins in methylotrophic yeast Pichia pastoris.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108595

30 October 2018

A common subunit structure in Clostridium botulinum type A, B and E toxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9746584

12 December 2020

based on heuristic

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Studies on immunity to toxins of Clostridium botulinum. VIII. Immunological response of man to purified bivalent AB botulinum toxoid

1 reference

https://pubmed.ncbi.nlm.nih.gov/9746584

12 December 2020

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STUDIES ON IMMUNITY TO TOXINS OF CLOSTRIDIUM BOTULINUM. IX. IMMUNOLOGIC RESPONSE OF MAN TO PURIFIED PENTAVALENT ABCDE BOTULINUM TOXIOD

1 reference

https://pubmed.ncbi.nlm.nih.gov/9746584

12 December 2020

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Heterologous combinations of heavy and light chains from botulinum neurotoxin A and tetanus toxin inhibit neurotransmitter release in Aplysia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9746584

12 December 2020

based on heuristic

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High-level expression of tetanus toxin fragment C in Pichia pastoris strains containing multiple tandem integrations of the gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/9746584

12 December 2020

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Proteolytic cleavage of synthetic fragments of vesicle-associated membrane protein, isoform-2 by botulinum type B neurotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9746584

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid Selection Using G418 of High Copy Number Transformants of Pichia pastoris for High–level Foreign Gene Expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/9746584

12 December 2020

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Analysis of the immune response to papain digestion products of tetanus toxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9746584

12 December 2020

based on heuristic

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Identifiers

10.1128/IAI.66.10.4817-4822.1998

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4 December 2019

1 reference

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4 December 2019

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