NF-kappaB as a primary regulator of the stress response (Q33771784)

29 July 2017

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title

NF-kappaB as a primary regulator of the stress response (English)

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29 July 2017

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Mercurio F

1

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29 July 2017

Manning AM

series ordinal

2

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29 July 2017

language of work or name

English

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publication date

1 November 1999

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29 July 2017

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29 July 2017

18

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29 July 2017

45

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29 July 2017

6163-6171

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203174

29 July 2017

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cites work

Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

NF-kappa B: ten years after

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Function and activation of NF-kappa B in the immune system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

The NF-kappa B and I kappa B proteins: new discoveries and insights

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

TPL-2 kinase regulates the proteolysis of the NF-kappaB-inhibitory protein NF-kappaB1 p105

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Reactive oxygen intermediate-dependent NF-kappaB activation by interleukin-1beta requires 5-lipoxygenase or NADPH oxidase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

The NF-kappa B transcription factor and cancer: high expression of NF-kappa B- and I kappa B-related proteins in tumor cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Transcriptional regulation of endothelial cell adhesion molecules: a dominant role for NF-kappa B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

The ubiquitin-proteasome pathway: on protein death and cell life

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Apoptosis in cancer therapy: crossing the threshold

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

The I kappa B proteins: members of a multifunctional family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

The ubiquitin system for protein degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Antisense inhibition of the p65 subunit of NF-kappa B blocks tumorigenicity and causes tumor regression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Gastric hyperplasia and increased proliferative responses of lymphocytes in mice lacking the COOH-terminal ankyrin domain of NF-kappaB2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Transmembrane redox signaling activates NF-kappaB in macrophages

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Activation of IkappaB kinase beta by protein kinase C isoforms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

IKK1-deficient mice exhibit abnormal development of skin and skeleton

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Signal transduction through NF-kappa B.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Ubiquitin-mediated processing of NF-kappa B transcriptional activator precursor p105. Reconstitution of a cell-free system and identification of the ubiquitin-carrier protein, E2, and a novel ubiquitin-protein ligase, E3, involved in conjugation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

The precursor of NF-kappa B p50 has I kappa B-like functions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

The role of hydroxyl radical as a messenger in the activation of nuclear transcription factor NFKB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Expression of the neoplastic phenotype by human thyroid carcinoma cell lines requires NFkappaB p65 protein expression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Activation of nuclear factor-kappaB-dependent transcription by tumor necrosis factor-alpha is mediated through phosphorylation of RelA/p65 on serine 529.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203174

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203174

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Dimensions Publication ID

29 July 2017

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1 reference