A point mutation in the groove of HLA-DO allows egress from the endoplasmic reticulum independent of HLA-DM. (Q33772095)

29 July 2017

title

A point mutation in the groove of HLA-DO allows egress from the endoplasmic reticulum independent of HLA-DM. (English)

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29 July 2017

main subject

endoplasmic reticulum

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author name string

Francis Deshaies

1

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29 July 2017

Alexandre Brunet

2

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29 July 2017

Djibril A Diallo

3

1 reference

29 July 2017

Lisa K Denzin

4

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29 July 2017

Angela Samaan

5

1 reference

29 July 2017

Jacques Thibodeau

6

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29 July 2017

language of work or name

English

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publication date

22 April 2005

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Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

published in

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29 July 2017

volume

102

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29 July 2017

issue

18

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29 July 2017

page(s)

6443-6448

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The expression of HLA-DO (H2-O) in B lymphocytes

29 July 2017

cites work

1 reference

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Downmodulation of antigen presentation by H2-O in B cell lines and primary B lymphocytes

28 July 2018

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Class II transactivator-induced expression of HLA-DO(beta) in HeLa cells

28 July 2018

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Identification of the lateral interaction surfaces of human histocompatibility leukocyte antigen (HLA)-DM with HLA-DR1 by formation of tethered complexes that present enhanced HLA-DM catalysis

28 July 2018

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Altered major histocompatibility complex class II peptide loading in H2-O-deficient mice

28 July 2018

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Conserved structural features between HLA-DO beta and -DR beta

28 July 2018

1 reference

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The tetraspan protein CD82 is a resident of MHC class II compartments where it associates with HLA-DR, -DM, and -DO molecules

28 July 2018

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A role for HLA-DO as a co-chaperone of HLA-DM in peptide loading of MHC class II molecules.

28 July 2018

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Crystal structure of I-Ak in complex with a dominant epitope of lysozyme

28 July 2018

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HLA-DO is a negative modulator of HLA-DM-mediated MHC class II peptide loading

28 July 2018

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Negative regulation by HLA-DO of MHC class II-restricted antigen processing

28 July 2018

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HLA-DO is an intracellular class II molecule with distinctive thymic expression

28 July 2018

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How HLA-DM edits the MHC class II peptide repertoire: survival of the fittest?

28 July 2018

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Signal-mediated sorting of membrane proteins between the endoplasmic reticulum and the golgi apparatus

28 July 2018

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HLA-DO is a lysosomal resident which requires association with HLA-DM for efficient intracellular transport

28 July 2018

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28 July 2018

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HLA-DQ allelic polymorphisms constrain patterns of class II heterodimer formation.

28 July 2018

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Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1.

28 July 2018

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A role for calnexin (IP90) in the assembly of class II MHC molecules

28 July 2018

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Assembly, transport, and function of MHC class II molecules

28 July 2018

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28 July 2018

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A lysosomal targeting signal in the cytoplasmic tail of the beta chain directs HLA-DM to MHC class II compartments.

28 July 2018

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The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif

28 July 2018

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Transfected human B lymphoblastoid cells express the mouse Ad beta-chain in association with DR alpha.

28 July 2018

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A novel HLA class II molecule (DR alpha-DQ beta) created by mismatched isotype pairing

28 July 2018

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Predominant role of amino-terminal sequences in dictating efficiency of class II major histocompatibility complex alpha beta dimer expression

28 July 2018

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Class II genes of the human major histocompatibility complex. The DO beta gene is a divergent member of the class II beta gene family

28 July 2018

1 reference

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Cell surface expression of hybrid murine/human MHC class II beta alpha dimers. Key influence of residues in the amino-terminal portion of the beta 1 domain

28 July 2018

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28 July 2018

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Defective intracellular transport as a common mechanism limiting expression of inappropriately paired class II major histocompatibility complex alpha/beta chains

28 July 2018

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HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides

28 July 2018

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The alpha chain gene of H-2O has an unexpected location in the major histocompatibility complex

28 July 2018

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Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO.

28 July 2018

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Functional analysis of tryptophans alpha 62 and beta 120 on HLA-DM.

21 January 2018

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Germinal center B cells regulate their capability to present antigen by modulation of HLA-DO.

21 January 2018

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Determination of the HLA-DM interaction site on HLA-DR molecules

21 January 2018

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Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides

21 January 2018

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HLA-DM induces clip dissociation from MHC class II αβ dimers and facilitates peptide loading

21 January 2018

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Association with BiP and aggregation of class II MHC molecules synthesized in the absence of invariant chain.

21 January 2018

1 reference

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Two populations of Ia-like molecules on a human B cell line.

30 October 2018

1 reference

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Unexpected expression of a unique mixed-isotype class II MHC molecule by transfected L-cells

30 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500853102

Regulation of MHC class II antigen presentation by sorting of recycling HLA-DM/DO and class II within the multivesicular body

21 January 2018

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12 December 2020

Novel polymorphisms in HLA-DOA and HLA-DOB in B-cell malignancies

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12 December 2020

Analysis of H2-O influence on antigen presentation by B cells

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12 December 2020

Analysis of monoclonal antibodies reactive with human class II beta chains by two-dimensional electrophoresis and Western blotting

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12 December 2020

HLA-DRα chain residues located on the outer loops are involved in nonpolymorphic and polymorphic antibody-binding epitopes

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12 December 2020

Immunochemically purified DR antigens in liposomes stimulate xenogeneic cytolytic T cells in secondary in vitro cultures

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12 December 2020

Functional characterization of a lysosomal sorting motif in the cytoplasmic tail of HLA-DObeta

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0500853102

1 reference

29 July 2017

0 references

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29 July 2017

1 reference