Proteomics investigations of drug-induced hepatotoxicity in HepG2 cells (Q33773197)

29 July 2017

title

Proteomics investigations of drug-induced hepatotoxicity in HepG2 cells (English)

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2

Johan Renes

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Edwin Mariman

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object named as

Edwin C M Mariman

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Jos C S Kleinjans

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Joost H M van Delft

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Anke Van Summeren

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Johan Renes

2

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Freek G Bouwman

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Jean-Paul Noben

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publication date

16 December 2010

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published in

Toxicological Sciences

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volume

120

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issue

1

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page(s)

109-122

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Effect of cyclosporin A on the biliary excretion of cholephilic compounds in rats

29 July 2017

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Phase I and II enzyme characterization of two sources of HepG2 cell lines

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Comparison of HepG2 and HepaRG by whole-genome gene expression analysis for the purpose of chemical hazard identification

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21 January 2018

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A toxicogenomics-based parallelogram approach to evaluate the relevance of coumarin-induced responses in primary human hepatocytes in vitro for humans in vivo.

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Cyclosporin A decreases apolipoprotein E secretion from human macrophages via a protein phosphatase 2B-dependent and ATP-binding cassette transporter A1 (ABCA1)-independent pathway

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Cyclosporin A traps ABCA1 at the plasma membrane and inhibits ABCA1-mediated lipid efflux to apolipoprotein A-I.

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The endoplasmic reticulum Ca2+ store: a view from the lumen

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

21 January 2018

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Hepatobiliary disease in patients with cystic fibrosis

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21 January 2018

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High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening

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21 January 2018

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Effect of cyclosporine on bile secretion in rats

21 January 2018

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Identification of the Multidrug Resistance-Related Membrane Glycoprotein as an Acceptor for Cyclosporine

21 January 2018

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Structure, function and regulation of carboxylesterases

21 January 2018

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Cytotoxic effects of 110 reference compounds on HepG2 cells and for 60 compounds on HeLa, ECC-1 and CHO cells. II mechanistic assays on NAD(P)H, ATP and DNA contents

21 January 2018

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Cytotoxic effects of 100 reference compounds on Hep G2 and HeLa cells and of 60 compounds on ECC-1 and CHO cells. I mechanistic assays on ROS, glutathione depletion and calcein uptake

21 January 2018

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Bile salt transporters: molecular characterization, function, and regulation

21 January 2018

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Interlaboratory evaluation of rat hepatic gene expression changes induced by methapyrilene

21 January 2018

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Phase II enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells

21 January 2018

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Identification of oxidative stress-related proteins for predictive screening of hepatotoxicity using a proteomic approach

21 January 2018

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Investigation of proteomic biomarkers in in vivo hepatotoxicity study of rat liver: toxicity differentiation in hepatotoxicants

21 January 2018

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Estrogen receptor alpha mediates 17alpha-ethynylestradiol causing hepatotoxicity

21 January 2018

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Inhibition of hepatocytary vesicular transport by cyclosporin A in the rat: relationship with cholestasis and hyperbilirubinemia

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/TOXSCI/KFQ380

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29 July 2017

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