Multisite phosphorylation provides an effective and flexible mechanism for switch-like protein degradation (Q33778197)

29 July 2017

title

Multisite phosphorylation provides an effective and flexible mechanism for switch-like protein degradation (English)

1 reference

29 July 2017

1 reference

S Marjan Varedi K

1

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29 July 2017

Alejandra C Ventura

series ordinal

2

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29 July 2017

Sofia D Merajver

series ordinal

3

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29 July 2017

Xiaoxia Nina Lin

series ordinal

4

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29 July 2017

language of work or name

English

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publication date

13 December 2010

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29 July 2017

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29 July 2017

volume

5

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29 July 2017

issue

12

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29 July 2017

page(s)

e14029

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Creative Commons Attribution 4.0 International

29 July 2017

copyright license

start time

13 December 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Multisite phosphorylation regulates Bim stability and apoptotic activity

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2

4 July 2018

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4 July 2018

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CDK Pho85 targets CDK inhibitor Sic1 to relieve yeast G1 checkpoint arrest after DNA damage

4 July 2018

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Sic1 is phosphorylated by CK2 on Ser201 in budding yeast cells

4 July 2018

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Saccharomyces cerevisiae Ime2 phosphorylates Sic1 at multiple PXS/T sites but is insufficient to trigger Sic1 degradation

4 July 2018

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Multisite M-phase phosphorylation of Xenopus Wee1A

4 July 2018

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Multisite protein phosphorylation makes a good threshold but can be a poor switch

4 July 2018

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4 July 2018

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4 July 2018

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Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1

4 July 2018

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Hog1 mediates cell-cycle arrest in G1 phase by the dual targeting of Sic1.

4 July 2018

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Integrative analysis of cell cycle control in budding yeast

4 July 2018

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Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades

4 July 2018

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SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

4 July 2018

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A positive-feedback-based bistable 'memory module' that governs a cell fate decision

4 July 2018

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Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

4 July 2018

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Mathematical modeling suggests cooperative interactions between a disordered polyvalent ligand and a single receptor site

4 July 2018

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4 July 2018

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4 July 2018

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Testing a mathematical model of the yeast cell cycle

4 July 2018

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Multisite phosphorylation and the countdown to S phase

4 July 2018

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Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

4 July 2018

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Differential regulation of retinoblastoma tumor suppressor protein by G(1) cyclin-dependent kinase complexes in vivo

4 July 2018

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Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase

4 July 2018

1 reference

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The regulation of protein function by multisite phosphorylation--a 25 year update

4 July 2018

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Kinetic analysis of a molecular model of the budding yeast cell cycle

4 July 2018

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Phosphorylation controls timing of Cdc6p destruction: A biochemical analysis

4 July 2018

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p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

4 July 2018

1 reference

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Emergent properties of networks of biological signaling pathways

4 July 2018

1 reference

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Phosphorylation of sic1, a cyclin-dependent kinase (Cdk) inhibitor, by Cdk including Pho85 kinase is required for its prompt degradation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001445

Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis

4 July 2018

1 reference

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Regulation of the G1 phase of the cell cycle by periodic stabilization and degradation of the p25rum1 CDK inhibitor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001445

Regulation of the replication initiator protein p65cdc18 by CDK phosphorylation

4 July 2018

1 reference

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F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001445

Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001445

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001445

Phosphorylation and proteolysis: partners in the regulation of cell division in budding yeast

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001445

Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001445

An inhibitor of yeast cyclin-dependent protein kinase plays an important role in ensuring the genomic integrity of daughter cells

4 July 2018

1 reference

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The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

4 July 2018

1 reference

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Amplification and adaptation in regulatory and sensory systems.

4 July 2018

1 reference

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An amplified sensitivity arising from covalent modification in biological systems

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001445

Ultrasensitivity in biochemical systems controlled by covalent modification. Interplay between zero-order and multistep effects

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001445

The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001445

Multisite and hierarchal protein phosphorylation.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001445

Superiority of interconvertible enzyme cascades in metabolic regulation: Analysis of multicyclic systems

4 July 2018

1 reference

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Temporal cooperativity and sensitivity amplification in biological signal transduction.

4 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0014029

Why do protein kinase cascades have more than one level?

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0014029

How responses get more switch-like as you move down a protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0014029

Allosteric regulation of the transcription factor NFAT1 by multiple phosphorylation sites: a mathematical analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0014029

Versatile regulation of multisite protein phosphorylation by the order of phosphate processing and protein-protein interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0014029

Coherence and timing of cell cycle start examined at single-cell resolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0014029

Multi-site phosphorylation of Pho4 by the cyclin-CDK Pho80-Pho85 is semi-processive with site preference

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0014029

Detection of sequential polyubiquitylation on a millisecond timescale

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0014029

Regulation of RUNX1/AML1 during the G2/M transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0014029

Multisite phosphorylation of Arabidopsis HFR1 by casein kinase II and a plausible role in regulating its degradation rate

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0014029

Rapid degradation of the G1 cyclin Cln2 induced by CDK-dependent phosphorylation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21179196

12 December 2020

inferred from PubMed ID database lookup

The yeast CDK inhibitor Sic1 prevents genomic instability by promoting replication origin licensing in late G(1)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21179196

12 December 2020

inferred from PubMed ID database lookup

Bistable biochemical switching and the control of the events of the cell cycle

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21179196

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1371/JOURNAL.PONE.0014029

1 reference

release_5mbzncnhkfgmrg74jc2lx5dydm

29 July 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5mbzncnhkfgmrg74jc2lx5dydm

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3001445

1 reference

29 July 2017

1 reference