A flavin-dependent halogenase catalyzes the chlorination step in the biosynthesis of Dictyostelium differentiation-inducing factor 1. (Q33778430)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20231486%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

A flavin-dependent halogenase catalyzes the chlorination step in the biosynthesis of Dictyostelium differentiation-inducing factor 1 (English)

1 reference

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1-((3,5-Dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone

19 January 2020

main subject

1 reference

ChEBI release 2020-05-28

3

1 reference

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19 January 2020

2

Christopher T Walsh

1 reference

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19 January 2020

author name string

Christopher S Neumann

series ordinal

1

1 reference

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19 January 2020

language of work or name

English

0 references

publication date

15 March 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20231486%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

19 January 2020

published in

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19 January 2020

volume

107

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19 January 2020

issue

13

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19 January 2020

page(s)

5798-5803

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Paracrine signaling in a bacterium

19 January 2020

cites work

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Functional Characterization of the Biosynthesis of Radicicol, an Hsp90 Inhibitor Resorcylic Acid Lactone from Chaetomium chiversii

4 July 2018

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Tandem action of the O2- and FADH2-dependent halogenases KtzQ and KtzR produce 6,7-dichlorotryptophan for kutzneride assembly

4 July 2018

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High-throughput analysis of spatio-temporal dynamics in Dictyostelium

4 July 2018

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Dictyostelium differentiation-inducing factor-1 induces glucose transporter 1 translocation and promotes glucose uptake in mammalian cells

4 July 2018

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Molecular basis for chloronium-mediated meroterpene cyclization: cloning, sequencing, and heterologous expression of the napyradiomycin biosynthetic gene cluster

4 July 2018

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4 July 2018

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Chlorination by a long-lived intermediate in the mechanism of flavin-dependent halogenases

4 July 2018

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Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase

4 July 2018

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Nature's inventory of halogenation catalysts: oxidative strategies predominate

4 July 2018

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Bacterial small-molecule signaling pathways

4 July 2018

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Tryptophan 7-halogenase (PrnA) structure suggests a mechanism for regioselective chlorination

4 July 2018

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The genome of the social amoeba Dictyostelium discoideum

4 July 2018

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Robust in vitro activity of RebF and RebH, a two-component reductase/halogenase, generating 7-chlorotryptophan during rebeccamycin biosynthesis

4 July 2018

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A rapid and efficient method to generate multiple gene disruptions in Dictyostelium discoideum using a single selectable marker and the Cre-loxP system

4 July 2018

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4 July 2018

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Characterization of a two-component alkanesulfonate monooxygenase from Escherichia coli

4 July 2018

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Cloning and nucleotide sequence of the gene responsible for chlorination of tetracycline

4 July 2018

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Differentiation-inducing factor from the slime mould Dictyostelium discoideum and its analogues. Synthesis, structure and biological activity

4 July 2018

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A specific DIF binding protein in Dictyostelium

4 July 2018

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Cell differentiation without morphogenesis in Dictyostelium discoideum

4 July 2018

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4 July 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The Biosynthesis of Differentiation-Inducing Factor, a Chlorinated Signal Molecule RegulatingDictyosteliumDevelopment

21 January 2018

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Migration ofDictyosteliumslugs: Anterior-like cells may provide the motive force for the prespore zone

21 January 2018

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21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20231486

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Structural requirements of Dictyostelium differentiation-inducing factors for their stalk-cell-inducing activity in Dictyostelium cells and anti-proliferative activity in K562 human leukemic cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20231486

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1001681107

1 reference

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19 January 2020

0 references

1 reference

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19 January 2020

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