Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3 (Q33780701)

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English	Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3	scientific article

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scholarly article

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30 January 2020

Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3 (English)

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30 January 2020

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apoptotic process

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Christine E Brown

2

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30 January 2020

author name string

Fan Yang

1

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30 January 2020

Ralf Buettner

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30 January 2020

Michael Hedvat

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30 January 2020

Renate Starr

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30 January 2020

Anna Scuto

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30 January 2020

Anne Schroeder

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30 January 2020

Michael Jensen

8

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30 January 2020

Richard Jove

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30 January 2020

publication date

6 April 2010

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30 January 2020

Molecular Cancer Therapeutics

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30 January 2020

9

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30 January 2020

4

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30 January 2020

953-962

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30 January 2020

Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas

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4 July 2018

Signal transducer and activator of transcription-3: a molecular hub for signaling pathways in gliomas

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Safety, pharmacokinetics, and preliminary antitumor activity of sorafenib: a review of four phase I trials in patients with advanced refractory solid tumors

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Molecular targets of glioma invasion.

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Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5.

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A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo

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Mechanisms of disease: Insights into the emerging role of signal transducers and activators of transcription in cancer

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The role of Mcl-1 downregulation in the proapoptotic activity of the multikinase inhibitor BAY 43-9006.

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Genetic pathways to glioblastomas

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Development of novel targeted therapies in the treatment of malignant glioma

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The STATs of cancer--new molecular targets come of age

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12 December 2020

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10.1158/1535-7163.MCT-09-0947

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30 January 2020

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30 January 2020

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