Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception (Q33780850)

29 July 2017

Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception (English)

1 reference

29 July 2017

multiple drug resistance

1 reference

1 reference

1 reference

8

Albert Dahan

1 reference

29 July 2017

Noam Zelcer

1

1 reference

29 July 2017

Koen van de Wetering

2

1 reference

29 July 2017

Michel Hillebrand

3

1 reference

29 July 2017

Elise Sarton

4

1 reference

29 July 2017

Annemieke Kuil

5

1 reference

29 July 2017

Peter R Wielinga

6

1 reference

29 July 2017

Thomas Tephly

7

1 reference

29 July 2017

Jos H Beijnen

9

1 reference

29 July 2017

Piet Borst

10

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29 July 2017

language of work or name

English

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publication date

10 May 2005

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29 July 2017

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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29 July 2017

102

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29 July 2017

7274-7279

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29 July 2017

20

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Mrp4 confers resistance to topotecan and protects the brain from chemotherapy

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Genetic polymorphisms in the multidrug resistance-associated protein 3 (ABCC3, MRP3) gene and relationship to its mRNA and protein expression in human liver

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

The MRP family of drug efflux pumps

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Influences on serum concentrations of morphine, M6G and M3G during routine clinical drug monitoring: a prospective survey in 300 adult cancer patients

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

The superfamily of organic anion transporting polypeptides

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Clinical pharmacology of opioids for pain

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Transport of bile acids in multidrug-resistance-protein 3-overexpressing cells co-transfected with the ileal Na+-dependent bile-acid transporter

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Mammalian ABC transporters in health and disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Expression and localization of the multidrug resistance-associated protein 3 in rat small and large intestine.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Tissue distribution and induction of human multidrug resistant protein 3

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Increased expression of multidrug resistance-associated protein 1 (mrp1) in hepatocyte basolateral membrane and renal tubular epithelia after bile duct ligation in rats

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3).

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Morphine-6-glucuronide: an analgesic of the future?

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Transport of opioids from the brain to the periphery by P-glycoprotein: peripheral actions of central drugs

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Transport of drugs across the hepatic sinusoidal membrane: sinusoidal drug influx and efflux in the liver

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Transport of amphipathic anions by human multidrug resistance protein 3

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Human UDP-glucuronosyltransferases: metabolism, expression, and disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Opioids in pain management

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

MRP3, an organic anion transporter able to transport anti-cancer drugs

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Hepatic expression of multidrug resistance-associated protein-like proteins maintained in eisai hyperbilirubinemic rats.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Human UGT2B7 catalyzes morphine glucuronidation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

The disposition of morphine and its 3- and 6-glucuronide metabolites in humans and animals, and the importance of the metabolites to the pharmacological effects of morphine.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Forensic drug testing for opiates. II. Metabolism and excretion rate of morphine in humans after morphine administration

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Species difference of site-selective glucuronidation of morphine

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

The ATP-dependent glutathione S-conjugate export pump

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Urinary excretion of morphine and its metabolites in morphine-dependent subjects

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Morphine-3beta-D-glucuronide suppresses inhibitory synaptic transmission in rat substantia gelatinosa

4 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502530102

Pharmacokinetic-pharmacodynamic modeling of morphine-6-glucuronide-induced analgesia in healthy volunteers: absence of sex differences

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502530102

Opiate-induced analgesia is increased and prolonged in mice lacking P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502530102

Evidence for an active transport of morphine-6-beta-d-glucuronide but not P-glycoprotein-mediated at the blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502530102

The disposition of morphine and morphine-3-glucuronide in the isolated perfused rat liver: effects of altered perfusate flow rate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502530102

Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502530102

Tumor necrosis factor alpha-dependent up-regulation of Lrh-1 and Mrp3(Abcc3) reduces liver injury in obstructive cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502530102

Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502530102

Pharmacokinetic differences of morphine and morphine-glucuronides are reflected in locomotor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502530102

Morphine-3-glucuronide--a potent antagonist of morphine analgesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502530102

Induction of multidrug resistance protein 3 (mrp3) in vivo is independent of constitutive androstane receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502530102

Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

High-performance liquid chromatographic determination of morphine and its 3- and 6-glucuronide metabolites by two-step solid-phase extraction.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091780

Comparison of the disposition of hepatically-generated morphine-3-glucuronide and morphine-6-glucuronide in isolated perfused liver from the guinea pig

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15886284

12 December 2020

inferred from PubMed ID database lookup

Enterohepatic recirculation and renal metabolism of morphine in the rat

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15886284

12 December 2020

inferred from PubMed ID database lookup

Pharmacology of irinotecan

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15886284

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.0502530102

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference