Structural and functional studies of UDP-glucuronosyltransferases (Q33781188)

29 July 2017

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title

Structural and functional studies of UDP-glucuronosyltransferases (English)

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29 July 2017

Radominska-Pandya A

1

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29 July 2017

Czernik PJ

2

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29 July 2017

Little JM

3

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29 July 2017

Battaglia E

4

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29 July 2017

Mackenzie PI

5

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29 July 2017

language of work or name

English

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publication date

1 November 1999

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29 July 2017

published in

Drug Metabolism Reviews

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29 July 2017

volume

31

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29 July 2017

issue

4

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29 July 2017

page(s)

817-899

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Morphine-6-glucuronide: analgesic effects and receptor binding profile in rats

29 July 2017

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Tissue-specific 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible expression of human UDP-glucuronosyltransferase UGT1A6.

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2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans

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Preferential expression of biotransformation enzymes in the olfactory organs of Drosophila melanogaster, the antennae

21 January 2018

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Identification of bilirubin UDP-GTs in the human alimentary tract in accordance with the gut as a putative metabolic organ

21 January 2018

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Immunocharacterization of UDP-glucuronyltransferase isoenzymes in human liver, intestine and kidney

21 January 2018

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Glucuronidation of bile acids in human liver, intestine and kidney. An in vitro study on hyodeoxycholic acid

21 January 2018

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Hepatic and extrahepatic glucuronidation of bile acids in man. Characterization of bile acid uridine 5'-diphosphate-glucuronosyltransferase in hepatic, renal, and intestinal microsomes

21 January 2018

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Drug glucuronidation by human renal UDP-glucuronosyltransferases.

21 January 2018

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Sex differences in drug conjugation and their consequences for drug toxicity. Sulfation, glucuronidation and glutathione conjugation

21 January 2018

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Genetic and environmental factors associated with variation of human xenobiotic glucuronidation and sulfation

21 January 2018

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Odorant signal termination by olfactory UDP glucuronosyl transferase

21 January 2018

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Proposed role of drug-metabolizing enzymes: regulation of steady state levels of the ligands that effect growth, homeostasis, differentiation, and neuroendocrine functions

21 January 2018

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Drug-metabolizing enzymes in ligand-modulated transcription

21 January 2018

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Cytochromes P450 and uridine triphosphate-glucuronosyltransferases: model autoantigens to study drug-induced, virus-induced, and autoimmune liver disease

21 January 2018

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Required buried alpha-helical structure in the bilirubin UDP-glucuronosyltransferase, UGT1A1, contains a nonreplaceable phenylalanine

21 January 2018

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A critical amino acid residue, asp446, in UDP-glucuronosyltransferase.

21 January 2018

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Structure and function of uridine diphosphate glucuronosyltransferases

21 January 2018

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Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation

21 January 2018

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Glucuronidation of 3'-azido-3'-deoxythymidine catalyzed by human liver UDP-glucuronosyltransferase. Significance of nucleoside hydrophobicity and inhibition by xenobiotics

21 January 2018

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Characterization of a new class of inhibitors of the recombinant human liver UDP-glucuronosyltransferase, UGT1*6.

21 January 2018

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Chemical modification of human UDP-glucuronosyltransferase UGT1*6 by diethyl pyrocarbonate: possible involvement of a histidine residue in the catalytic process.

21 January 2018

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Expression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic UGT1A8

21 January 2018

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cDNA cloning and characterization of the human UDP glucuronosyltransferase, UGT1A3

21 January 2018

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Cloning and expression of human UDP-glucuronosyltransferase (UGT) 1A8.

21 January 2018

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Glucuronidation of thyroid hormone by human bilirubin and phenol UDP-glucuronyltransferase isoenzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily

21 January 2018

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https://api.crossref.org/works/10.1081%2FDMR-100101944

Isolation and characterization of a novel cDNA encoding a human UDP-glucuronosyltransferase active on C19 steroids

21 January 2018

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Validation and use of cloned, expressed human drug-metabolizing enzymes in heterologous cells for analysis of drug metabolism and drug-drug interactions

21 January 2018

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Investigations on the kinetic properties of estrone glucuronyltransferase from pig kidney

21 January 2018

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Investigation of the substrate specificity of a cloned expressed human bilirubin UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation

21 January 2018

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https://api.crossref.org/works/10.1081%2FDMR-100101944

Commentary: Control of UDP-glucuronyltransferase activity

21 January 2018

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'Coupled transglucuronidation': a new tool for studying the latency of UDP-glucuronyl transferase

21 January 2018

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https://api.crossref.org/works/10.1081%2FDMR-100101944

Guinea pig liver microsomal UDP-glucuronyltransferase: compartmented or phospholipid-constrained?

21 January 2018

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Summary of a novel, three-component regulatory model for uridine diphosphate glucuronyltransferase

21 January 2018

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Cloning of cDNAs coding for rat hepatic microsomal UDP-glucuronyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

Mutational analysis of the carboxy-terminal region of UDP-glucuronosyltransferase 2B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

An investigation of the transverse topology of bilirubin UDP-glucuronosyltransferase in rat hepatic endoplasmic reticulum

21 January 2018

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Topology and regulation of bilirubin UDP-glucuronyltransferase in sealed native microsomes from rat liver.

21 January 2018

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Topological disposition of UDP-glucuronyltransferase in rat liver microsomes

21 January 2018

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Mechanism of stimulation of microsomal UDP-glucuronosyltransferase by UDP-N-acetylglucosamine

21 January 2018

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Uridine diphosphoxylose enhances hepatic microsomal UDP-glucuronosyltransferase activity by stimulating transport of UDP-glucuronic acid across the endoplasmic reticulum membrane

21 January 2018

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ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2.

21 January 2018

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Human mast cells secreting leukotriene C4 express the MRP1 gene-encoded conjugate export pump

21 January 2018

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Expression of the apical conjugate export pump, Mrp2, in the polarized hepatoma cell line, WIF-B.

21 January 2018

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Evidence for an UDP-glucuronic acid/phenol glucuronide antiport in rat liver microsomal vesicles

21 January 2018

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Specific inactivation of the phosphohydrolase component of the hepatic microsomal glucose-6-phosphatase system by diethyl pyrocarbonate

21 January 2018

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Inhibition of bilirubin UDPglucuronosyltransferase activity by triphenylacetic acid and related compounds

21 January 2018

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Novel inhibitors and substrates of bilirubin: UDP-glucuronosyltransferase. Arylalkylcarboxylic acids

21 January 2018

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Isolation and characterization of hyodeoxycholic-acid: UDP-glucuronosyltransferase from human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

Photoaffinity labelling of glycosyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

Bile acid glucuronidation by rat liver microsomes and cDNA-expressed UDP-glucuronosyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

Nucleotide photoaffinity labeling of protein kinase subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

Excretion in dog bile of glucose and xylose conjugates of bilirubin

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

Formation of bilirubin glucoside

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

Bilirubin mono- and di-glucuronide formation by purified rat liver microsomal bilirubin UDP-glucuronyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

Studies of mammalian glucoside conjugation

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

A membrane transporter mediates access of uridine 5'-diphosphoglucuronic acid from the cytosol into the endoplasmic reticulum of rat hepatocytes: implications for glucuronidation reactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

New developments in glucuronidation research: report of a workshop on "glucuronidation, its role in health and disease"

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

A functional role for histidyl residues of the UDP-glucuronic acid carrier in rat liver endoplasmic reticulum membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

Functional expression of zeaxanthin glucosyltransferase from Erwinia herbicola and a proposed uridine diphosphate binding site

21 January 2018

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https://api.crossref.org/works/10.1081%2FDMR-100101944

Proteolytic mapping of the thymidine/thymidylate binding site of herpes simplex virus type 1 thymidine kinase: a general photoaffinity labeling method for identifying active-site peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

Affinity labeling of purine nucleotide sites in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

Interactions between the mitochondrial adenosinetriphosphatase and periodate-oxidized adenosine 5'-triphosphate, an affinity label for adenosine 5'-triphosphate binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

Identification of the Active Sites of Human and Schistosomal Hypoxanthine-Guanine Phosphoribosyltransferases by GMP-2',3'-dialdehyde Affinity Labeling

21 January 2018

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Inhibition of hyaluronate synthesis

21 January 2018

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https://api.crossref.org/works/10.1081%2FDMR-100101944

Inactivation of Escherichia coli phosphoribosylpyrophosphate synthetase by the 2',3'-dialdehyde derivative of ATP. Identification of active site lysines

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

Cloning and substrate specificity of a human phenol UDP-glucuronosyltransferase expressed in COS-7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

Photoaffinity labeling of retinoic acid-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

Three-dimensional structure of galactose-1-phosphate uridylyltransferase from Escherichia coli at 1.8 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

The human gene CGT encoding the UDP-galactose ceramide galactosyl transferase (cerebroside synthase): cloning, characterization, and assignment to human chromosome 4, band q26

21 January 2018

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https://api.crossref.org/works/10.1081%2FDMR-100101944

The complete DNA sequence of Autographa californica nuclear polyhedrosis virus

21 January 2018

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Cloning and characterization of two genes from Streptomyces lividans that confer inducible resistance to lincomycin and macrolide antibiotics

21 January 2018

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https://api.crossref.org/works/10.1081%2FDMR-100101944

Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450's

21 January 2018

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Computer modeling of 3D structures of cytochrome P450s

21 January 2018

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Crystal structures of cellular retinoic acid binding proteins I and II in complex with all-trans-retinoic acid and a synthetic retinoid

21 January 2018

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https://api.crossref.org/works/10.1081%2FDMR-100101944

Cloning and stable expression of a new member of the human liver phenol/bilirubin: UDP-glucuronosyltransferase cDNA family

21 January 2018

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Characterization and prevalence of a polymorphism in the 3' untranslated region of cytochrome P4501A1 in cancer-prone Atlantic tomcod

21 January 2018

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Molecular cloning and functional analysis of cynomolgus monkey CYP1A2.

21 January 2018

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The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes

21 January 2018

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Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily

21 January 2018

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The sequence of human serum albumin cDNA and its expression in E. coli

21 January 2018

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Isolation and characterization of a human orphan UDP-glucuronosyltransferase, UGT2B11.

21 January 2018

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Isolation and characterization of UGT2B15(Y85): a UDP-glucuronosyltransferase encoded by a polymorphic gene

21 January 2018

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Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: pharmacological implications

21 January 2018

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Glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4, 5-b]pyridine by human microsomal UDP-glucuronosyltransferases: identification of specific UGT1A family isoforms involved.

21 January 2018

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Drug and xenobiotic glucuronidation catalysed by cloned human liver UDP-Glucuronosyltransferases stably expressed in tissue culture cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

The human UDP glucuronosyltransferase, UGT1A10, glucuronidates mycophenolic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

Selective and potent inhibition of different hepatic UDP-glucuronosyltransferase activities by ω,ω,ω-triphenylalcohols and UDP derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

Purification and Characterization of a Catalytically Active Human Liver UDP-Glucuronosyltransferase Expressed as a Fusion Protein in E. coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

Determination of the Human Liver UDP-Glucuronosyltransferase 2B4 Domains Involved in the Binding of UDP-Glucuronic Acid Using Photoaffinity Labeling of Fusion Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-100101944

21 January 2018

Identifiers

DOI

10.1081/DMR-100101944

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29 July 2017

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