Human carboxymethylenebutenolidase as a bioactivating hydrolase of olmesartan medoxomil in liver and intestine (Q33782444)

29 July 2017

Human carboxymethylenebutenolidase as a bioactivating hydrolase of olmesartan medoxomil in liver and intestine (English)

1 reference

29 July 2017

Tomoko Ishizuka

1

1 reference

29 July 2017

Izumi Fujimori

2

1 reference

29 July 2017

Mitsunori Kato

3

1 reference

29 July 2017

Chisa Noji-Sakikawa

4

1 reference

29 July 2017

Motoko Saito

5

1 reference

29 July 2017

Yasushi Yoshigae

6

1 reference

29 July 2017

Kazuishi Kubota

7

1 reference

29 July 2017

Atsushi Kurihara

8

1 reference

29 July 2017

Takashi Izumi

9

1 reference

29 July 2017

Toshihiko Ikeda

10

1 reference

29 July 2017

Osamu Okazaki

11

1 reference

29 July 2017

language of work or name

English

0 references

publication date

19 February 2010

1 reference

Journal of Biological Chemistry

29 July 2017

1 reference

29 July 2017

285

1 reference

29 July 2017

16

1 reference

29 July 2017

11892-11902

1 reference

Efficacy in angiotensin receptor blockade: a comparative review of data with olmesartan

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Alpha/beta hydrolase fold: an update

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Amlodipine/ARB fixed-dose combinations for the treatment of hypertension: focus on amlodipine/olmesartan combination

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Olmesartan medoxomil: a review of its use in the management of hypertension

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Structure and catalytic properties of carboxylesterase isozymes involved in metabolic activation of prodrugs

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Molecular Basis of Prodrug Activation by Human Valacyclovirase, an -Amino Acid Ester Hydrolase

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

The Pfam protein families database

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Faropenem: review of a new oral penem

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Large-scale mapping of human protein-protein interactions by mass spectrometry

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Structure, function and regulation of carboxylesterases

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Human carboxylesterase isozymes: catalytic properties and rational drug design

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Enzymes involved in the bioconversion of ester-based prodrugs

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

MODBASE: a database of annotated comparative protein structure models and associated resources

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

The importance of high-density lipoproteins for paraoxonase-1 secretion, stability, and activity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Lessons learned from marketed and investigational prodrugs

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Design of ester prodrugs to enhance oral absorption of poorly permeable compounds: challenges to the discovery scientist

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Pharmacogenetics of paraoxonases: a brief review

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Proteome analysis of secreted proteins during osteoclast differentiation using two different methods: Two‐dimensional electrophoresis and isotope‐coded affinity tags analysis with two‐dimensional chromatography

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Identification of a human valacyclovirase: biphenyl hydrolase-like protein as valacyclovir hydrolase

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Candesartan cilexetil: an update of its use in essential hypertension

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

The cholinesterases: from genes to proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Chemical structure and biodegradability of halogenated aromatic compounds. Conversion of chlorinated muconic acids into maleoylacetic acid

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Dienelactone hydrolase from Pseudomonas sp. strain B13

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Pharmacokinetic study of lenampicillin (KBT-1585) in healthy volunteers

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Refined structure of dienelactone hydrolase at 1.8 A

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Thiol protease-like active site found in the enzyme dienelactone hydrolase: Localization using biochemical, genetic, and structural tools

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

The alpha/beta hydrolase fold

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

Prodrug research: futile or fertile?

4 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.072629

Toxicological implications of esterases--from molecular structures to functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.072629

Metabolism of melatonin by human cytochromes p450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.072629

Rapid method for the quantification of amoxicillin and its major metabolites in pig tissues by liquid chromatography-tandem mass spectrometry with emphasis on stability issues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.072629

Hydrolysis of angiotensin II receptor blocker prodrug olmesartan medoxomil by human serum albumin and identification of its catalytic active sites

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

The pharmacokinetic and metabolic profile of olmesartan medoxomil limits the risk of clinically relevant drug interaction.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852926

3-Hydroxy-alpha-methyltyrosine progenitors: synthesis and evaluation of some (2-oxo-1,3-dioxol-4-yl)methyl esters

30 October 2018

1 reference

12 December 2020

Studies on prodrugs. II. Preparation and characterization of (5-substituted 2-oxo-1,3-dioxolen-4-yl)methyl esters of ampicillin.

1 reference

12 December 2020

X-ray crystallographic structure of dienelactone hydrolase at 2.8 A

1 reference

12 December 2020

Catalysis by dienelactone hydrolase: a variation on the protease mechanism

1 reference

12 December 2020

A theoretical study of substrate-induced activation of dienelactone hydrolase

1 reference

12 December 2020

Paraoxonase has a major role in the hydrolysis of prulifloxacin (NM441), a prodrug of a new antibacterial agent

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.072629

1 reference

release_yghpcv2yejhhvn4tz34ojzmvha

29 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/yghpcv2yejhhvn4tz34ojzmvha

24 November 2022

mapped directly with Wikidata item

PMCID

2852926

1 reference

29 July 2017

1 reference