Shp2 protein tyrosine phosphatase inhibitor activity of estramustine phosphate and its triterpenoid analogs (Q33782482)

29 July 2017

title

Shp2 protein tyrosine phosphatase inhibitor activity of estramustine phosphate and its triterpenoid analogs (English)

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29 July 2017

Latanya M Scott

1

1 reference

29 July 2017

Liwei Chen

2

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29 July 2017

Kenyon G Daniel

3

1 reference

29 July 2017

Wesley H Brooks

4

1 reference

29 July 2017

Wayne C Guida

5

1 reference

29 July 2017

Harshani R Lawrence

6

1 reference

29 July 2017

Said M Sebti

7

1 reference

29 July 2017

Nicholas J Lawrence

8

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29 July 2017

Jie Wu

9

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29 July 2017

language of work or name

English

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publication date

4 December 2010

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Bioorganic & Medicinal Chemistry Letters

29 July 2017

published in

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29 July 2017

volume

21

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29 July 2017

issue

2

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29 July 2017

page(s)

730-733

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Synthesis and antitumour activity of glycyrrhetinic acid derivatives

29 July 2017

cites work

1 reference

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Inhibition of cellular Shp2 activity by a methyl ester analog of SPI-112.

4 July 2018

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Targeting protein tyrosine phosphatases for anticancer drug discovery

4 July 2018

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Salicylic Acid Based Small Molecule Inhibitor for the Oncogenic Src Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 (SHP2)

4 July 2018

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The protein tyrosine phosphatase SHP-2 is required for EGFRvIII oncogenic transformation in human glioblastoma cells.

4 July 2018

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The therapeutic potential of phosphatase inhibitors

4 July 2018

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Molecular mechanism for SHP2 in promoting HER2-induced signaling and transformation

4 July 2018

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Large-scale structural analysis of the classical human protein tyrosine phosphatome

4 July 2018

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Inhibition of IFN-gamma-induced STAT1 tyrosine phosphorylation by human CMV is mediated by SHP2.

4 July 2018

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Inhibitors of Src homology-2 domain containing protein tyrosine phosphatase-2 (Shp2) based on oxindole scaffolds

4 July 2018

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4 July 2018

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CDC25 phosphatases in cancer cells: key players? Good targets?

4 July 2018

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Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer.

4 July 2018

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PTPN11 is the first identified proto-oncogene that encodes a tyrosine phosphatase

4 July 2018

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Discovery of a novel shp2 protein tyrosine phosphatase inhibitor

4 July 2018

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Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice

4 July 2018

1 reference

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Protein-tyrosine phosphatases and cancer

4 July 2018

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Glycyrrhetic acid (a metabolic substance and aglycon of glycyrrhizin) induces apoptosis in human hepatoma, promyelotic leukemia and stomach cancer cells.

4 July 2018

1 reference

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Protein tyrosine phosphatases in the human genome

4 July 2018

1 reference

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The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling

4 July 2018

1 reference

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Aminosterols from the dogfish shark Squalus acanthias

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034307

Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034307

Squalamine inhibits angiogenesis and solid tumor growth in vivo and perturbs embryonic vasculature

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034307

Inhibition of PTP1B by trodusquemine (MSI-1436) causes fat-specific weight loss in diet-induced obese mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034307

Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034307

30 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21193311

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

3-Methoxy-1,3,5(10)-estratriene-17(R)-spiro-6'-(2'-(bis-(2-chloroethyl)amino)-2'-oxo-1'oxa-3aza-2'-phosphorane)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21193311

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BMCL.2010.11.117

1 reference

29 July 2017

1 reference

29 July 2017

1 reference