Neuronal transporters regulate glutamate clearance, NMDA receptor activation, and synaptic plasticity in the hippocampus (Q33783651)

29 July 2017

title

Neuronal transporters regulate glutamate clearance, NMDA receptor activation, and synaptic plasticity in the hippocampus (English)

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29 July 2017

1 reference

Annalisa Scimemi

1

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author name string

Hua Tian

series ordinal

2

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29 July 2017

Jeffrey S Diamond

series ordinal

3

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29 July 2017

language of work or name

English

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publication date

1 November 2009

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29 July 2017

published in

Journal of Neuroscience

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29 July 2017

volume

29

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29 July 2017

issue

46

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29 July 2017

page(s)

14581-14595

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Receptor actions of synaptically released glutamate: the role of transporters on the scale from nanometers to microns

29 July 2017

cites work

1 reference

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Early intermediates in the transport cycle of the neuronal excitatory amino acid carrier EAAC1

4 July 2018

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Glutamate translocation of the neuronal glutamate transporter EAAC1 occurs within milliseconds

4 July 2018

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Differential synaptic localization of the glutamate transporter EAAC1 and glutamate receptor subunit GluR2 in the rat hippocampus

4 July 2018

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Subtype-dependence of NMDA receptor channel open probability.

4 July 2018

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The incorporation of NMDA receptors with a distinct subunit composition at nascent hippocampal synapses in vitro

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Glutamate transporter EAAC-1-deficient mice develop dicarboxylic aminoaciduria and behavioral abnormalities but no neurodegeneration

4 July 2018

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Detection of spontaneous synaptic events with an optimally scaled template

4 July 2018

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Flux coupling in a neuronal glutamate transporter

4 July 2018

1 reference

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Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate

4 July 2018

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Amplitude fluctuations of dual-component EPSCs in hippocampal pyramidal cells: implications for long-term potentiation.

4 July 2018

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Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors

4 July 2018

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Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex

4 July 2018

1 reference

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Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

4 July 2018

1 reference

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Pharmacological properties of recombinant human N-methyl-D-aspartate receptors comprising NR1a/NR2A and NR1a/NR2B subunit assemblies expressed in permanently transfected mouse fibroblast cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853250

Ifenprodil blocks N-methyl-D-aspartate receptors by a two-component mechanism.

4 July 2018

1 reference

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NMDA channel behavior depends on agonist affinity

4 July 2018

1 reference

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Contribution of hippocampal and extra-hippocampal NR2B-containing NMDA receptors to performance on spatial learning tasks

4 July 2018

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Activation of NR2B-containing NMDA receptors is not required for NMDA receptor-dependent long-term depression

30 October 2018

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Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse.

30 October 2018

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Deriving the glutamate clearance time course from transporter currents in CA1 hippocampal astrocytes: transmitter uptake gets faster during development.

30 October 2018

1 reference

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Extracellular diffusivity determines contribution of high-versus low-affinity receptors to neural signaling

30 October 2018

1 reference

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Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression.

30 October 2018

1 reference

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Modulation of glutamate mobility reveals the mechanism underlying slow-rising AMPAR EPSCs and the diffusion coefficient in the synaptic cleft

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853250

Extrasynaptic NR2B and NR2D subunits of NMDA receptors shape 'superslow' afterburst EPSC in rat hippocampus

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853250

Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853250

Cooperation between independent hippocampal synapses is controlled by glutamate uptake

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853250

Neuronal glutamate transporters limit activation of NMDA receptors by neurotransmitter spillover on CA1 pyramidal cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853250

An evaluation of synapse independence.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853250

Requirement of appropriate glutamate concentrations in the synaptic cleft for hippocampal LTP induction

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853250

The arrangement of glutamate receptors in excitatory synapses

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853250

Transporters buffer synaptically released glutamate on a submillisecond time scale.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853250

NR2A subunit expression shortens NMDA receptor synaptic currents in developing neocortex.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853250

Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853250

A novel mechanism of activity-dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853250

Ca2+ signaling requirements for long-term depression in the hippocampus

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853250

Kinetics of a human glutamate transporter.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853250

Synaptically released glutamate does not overwhelm transporters on hippocampal astrocytes during high-frequency stimulation

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19923291

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Extrasynaptic Glutamate Spillover in the Hippocampus: Dependence on Temperature and the Role of Active Glutamate Uptake

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19923291

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/JNEUROSCI.4845-09.2009

1 reference

29 July 2017

1 reference

29 July 2017

1 reference