Caveolins sequester FA on the cytoplasmic leaflet of the plasma membrane, augment triglyceride formation, and protect cells from lipotoxicity. (Q33784608)

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English	Caveolins sequester FA on the cytoplasmic leaflet of the plasma membrane, augment triglyceride formation, and protect cells from lipotoxicity.	scientific article

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30 January 2020

Caveolins sequester FA on the cytoplasmic leaflet of the plasma membrane, augment triglyceride formation, and protect cells from lipotoxicity (English)

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30 January 2020

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Michael T Kirber

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30 January 2020

Kellen Brunaldi

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30 January 2020

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30 January 2020

Jeffrey R Simard

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Jeffrey R Simard

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30 January 2020

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Tova Meshulam

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30 January 2020

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Biju K Pillai

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30 January 2020

Su Xu

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30 January 2020

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1 May 2010

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30 January 2020

Journal of Lipid Research

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30 January 2020

51

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30 January 2020

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30 January 2020

914-922

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30 January 2020

Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance

1 reference

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4 July 2018

IRS1-independent defects define major nodes of insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853459

4 July 2018

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

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4 July 2018

PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853459

4 July 2018

Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance

1 reference

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4 July 2018

A critical role of cavin (polymerase I and transcript release factor) in caveolae formation and organization.

1 reference

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4 July 2018

Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis

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4 July 2018

Nur77 coordinately regulates expression of genes linked to glucose metabolism in skeletal muscle

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4 July 2018

Cellular spelunking: exploring adipocyte caveolae

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4 July 2018

The multiple faces of caveolae

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4 July 2018

Fatty acid metabolism in adipocytes: functional analysis of fatty acid transport proteins 1 and 4.

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4 July 2018

Lipid droplets: a unified view of a dynamic organelle

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4 July 2018

Role of caveolin-1 and cholesterol in transmembrane fatty acid movement.

1 reference

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4 July 2018

Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells

1 reference

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4 July 2018

Activation of CCAAT/enhancer-binding protein (C/EBP) alpha expression by C/EBP beta during adipogenesis requires a peroxisome proliferator-activated receptor-gamma-associated repression of HDAC1 at the C/ebp alpha gene promoter.

1 reference

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4 July 2018

Fatty acid transport and metabolism in HepG2 cells.

1 reference

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4 July 2018

Dissociation of insulin receptor expression and signaling from caveolin-1 expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853459

4 July 2018

Physical landscapes in biological membranes: physico-chemical terrains for spatio-temporal control of biomolecular interactions and behaviour.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853459

4 July 2018

Role of caveolae and caveolins in health and disease

1 reference

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4 July 2018

Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes

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4 July 2018

Fatty acid interactions with proteins: what X-ray crystal and NMR solution structures tell us.

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4 July 2018

A simple method for the isolation and purification of total lipides from animal tissues

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853459

4 July 2018

Lipotoxicity: when tissues overeat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853459

4 July 2018

Lipotoxic diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853459

4 July 2018

Effects of the membrane dipole potential on the interaction of saquinavir with phospholipid membranes and plasma membrane receptors of Caco-2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853459

4 July 2018

Caveolin-2 is targeted to lipid droplets, a new "membrane domain" in the cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853459

4 July 2018

Accumulation of caveolin in the endoplasmic reticulum redirects the protein to lipid storage droplets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853459

4 July 2018

A caveolin dominant negative mutant associates with lipid bodies and induces intracellular cholesterol imbalance

1 reference

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4 July 2018

Interactions between metabolism and intracellular distribution of cholesterol and sphingomyelin

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4 July 2018

Identification of caveolin-1 as a fatty acid binding protein

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853459

4 July 2018

Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats

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4 July 2018

Intracellular pH in adipocytes: effects of free fatty acid diffusion across the plasma membrane, lipolytic agonists, and insulin

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4 July 2018

Oligomerization of VIP21-caveolin in vitro is stabilized by long chain fatty acylation or cholesterol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853459

4 July 2018

Caveolin is palmitoylated on multiple cysteine residues. Palmitoylation is not necessary for localization of caveolin to caveolae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2853459

4 July 2018

Interactions of macromolecules with the mammalian cell surface

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4 July 2018

pH gradients across phospholipid membranes caused by fast flip-flop of un-ionized fatty acids

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4 July 2018

Fatty acid flip-flop in a model membrane is faster than desorption into the aqueous phase

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30 October 2018

Cholesterol-induced caveolin targeting to lipid droplets in adipocytes: a role for caveolar endocytosis

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30 October 2018

Structural insights into the function of human caveolin 1.

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30 October 2018

Triacylglycerol is synthesized in a specific subclass of caveolae in primary adipocytes.

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30 October 2018

Chinese hamster ovary K2 cell lipid droplets appear to be metabolic organelles involved in membrane traffic

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30 October 2018

Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities

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30 October 2018

Glucose and palmitic acid induce degeneration of myofibrils and modulate apoptosis in rat adult cardiomyocytes

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30 October 2018

Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation.

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30 October 2018

Palmitate-induced apoptosis can occur through a ceramide-independent pathway

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30 October 2018

A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism.

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30 October 2018

Autolysis of isolated adipocytes by endogenously produced fatty acids

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid Flip-flop of Oleic Acid across the Plasma Membrane of Adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20388923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efflux of Cholesterol from Different Cellular Pools†

1 reference

https://pubmed.ncbi.nlm.nih.gov/20388923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1194/JLR.M900251

1 reference

Europe PubMed Central

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30 January 2020

PMC publication ID

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30 January 2020

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30 January 2020

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