BRCA1, BRCA2 and their possible function in DNA damage response (Q33786462)

29 July 2017

2 references

24 January 2021

17 February 2023

BRCA1, BRCA2 and their possible function in DNA damage response (English)

1 reference

29 July 2017

1 reference

24 January 2021

2 references

24 January 2021

17 February 2023

1 reference

18 December 2019

1 reference

22 December 2020

1 reference

1

Kote-Jarai Z

1 reference

29 July 2017

2

Eeles RA

2 references

29 July 2017

ORCID Public Data File 2021

language of work or name

English

0 references

publication date

1 December 1999

9 references

British Journal of Cancer

29 July 2017

13 March 2019

3 April 2019

17 June 2019

18 December 2019

22 December 2019

22 December 2020

24 January 2021

17 February 2023

9 references

29 July 2017

13 March 2019

3 April 2019

17 June 2019

18 December 2019

22 December 2019

22 December 2020

24 January 2021

17 February 2023

81

1 reference

29 July 2017

issue

7

1 reference

29 July 2017

page(s)

1099-1102

1 reference

Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

29 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

BRCA2 associates with acetyltransferase activity when bound to P/CAF

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

The BRCA2 gene product functionally interacts with p53 and RAD51

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

BRCA1 binds c-Myc and inhibits its transcriptional and transforming activity in cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Double-strand break repair deficiency and radiation sensitivity in BRCA2 mutant cancer cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Involvement of Brca2 in DNA repair

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

The BRCA2 is a histone acetyltransferase

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Regulation of BRCA1 and BRCA2 expression in human breast cancer cells by DNA-damaging agents

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

A BRCA1 nonsense mutation causes exon skipping

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

BRCA1, BRCA2, and DNA damage response: collision or collusion?

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Brca2 is required for embryonic cellular proliferation in the mouse

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Human BRCA1 inhibits growth in yeast: potential use in diagnostic testing

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

BRCA1 is a component of the RNA polymerase II holoenzyme

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Transcriptional activation functions in BRCA2

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

BRCA1 expression is not directly responsive to estrogen

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Association of BRCA1 with Rad51 in mitotic and meiotic cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Localization of BRCA1 and a splice variant identifies the nuclear localization signal

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Evidence for a transcriptional activation function of BRCA1 C-terminal region

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammary epithelial cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Cell cycle regulation of BRCA1 messenger RNA in human breast epithelial cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

BRCA1 expression is induced before DNA synthesis in both normal and tumor-derived breast cells.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Identification of the breast cancer susceptibility gene BRCA2

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Brca1 and Brca2 expression patterns in mitotic and meiotic cells of mice.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

NF-kappa B activation by ultraviolet light not dependent on a nuclear signal.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2374315

Loss of heterozygosity in familial tumors from three BRCA1-linked kindreds

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10584867

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Hereditary breast cancer: pathobiology, prognosis, and BRCA1 and BRCA2 gene linkage

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10584867

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Transcriptional activation by BRCA1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10584867

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.BJC.6690814

1 reference

Dimensions Publication ID

29 July 2017

0 references

1 reference

29 July 2017

1 reference