Increased bone marrow interleukin-7 (IL-7)/IL-7R levels but reduced IL-7 responsiveness in HIV-positive patients lacking CD4+ gain on antiviral therapy (Q33786846)

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English	Increased bone marrow interleukin-7 (IL-7)/IL-7R levels but reduced IL-7 responsiveness in HIV-positive patients lacking CD4+ gain on antiviral therapy	scientific article

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

Increased bone marrow interleukin-7 (IL-7)/IL-7R levels but reduced IL-7 responsiveness in HIV-positive patients lacking CD4+ gain on antiviral therapy (English)

1 reference

Europe PubMed Central

29 July 2017

Antonella d'Arminio Monforte

9

object named as

Antonella d'Arminio Monforte

1 reference

Europe PubMed Central

29 July 2017

object named as

Chiara Orlandi

4

0 references

Giulia Marchetti

object named as

Giulia Marchetti

10

0 references

object named as

Massimo Galli

7

0 references

8

object named as

Mauro Magnani

1 reference

Europe PubMed Central

29 July 2017

Anna Casabianca

2

object named as

Anna Casabianca

1 reference

Europe PubMed Central

29 July 2017

author name string

Giusi Maria Bellistrì

1

1 reference

Europe PubMed Central

29 July 2017

Esther Merlini

3

1 reference

Europe PubMed Central

29 July 2017

Giulio Ferrario

5

1 reference

Europe PubMed Central

29 July 2017

Luca Meroni

6

1 reference

Europe PubMed Central

29 July 2017

language of work or name

0 references

publication date

31 December 2010

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

5

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Europe PubMed Central

29 July 2017

e15663

1 reference

Europe PubMed Central

29 July 2017

12

1 reference

Europe PubMed Central

29 July 2017

copyright license

Creative Commons Attribution 4.0 International

31 December 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

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IL-7 induces rapid clathrin-mediated internalization and JAK3-dependent degradation of IL-7Ralpha in T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

4 July 2018

Responsiveness of T cells to interleukin-7 is associated with higher CD4+ T cell counts in HIV-1-positive individuals with highly active antiretroviral therapy-induced viral load suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

4 July 2018

IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

4 July 2018

Interleukin-7 receptor signaling is deficient in CD4+ T cells from HIV-infected persons and is inversely associated with aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

4 July 2018

The absence of CD4+ T cell count recovery despite receipt of virologically suppressive highly active antiretroviral therapy: clinical risk, immunological gaps, and therapeutic options

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

4 July 2018

CD4+ count and risk of non-AIDS diseases following initial treatment for HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

4 July 2018

Clinical outcome of HIV-infected antiretroviral-naive patients with discordant immunologic and virologic responses to highly active antiretroviral therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

4 July 2018

IL-7 and IL-15: therapeutic cytokines for immunodeficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

4 July 2018

Disrupting T-cell homeostasis: how HIV-1 infection causes disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

4 July 2018

Interleukin-7: from bench to clinic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

4 July 2018

IL-7 is critical for homeostatic proliferation and survival of naive T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

4 July 2018

A potential role for interleukin-7 in T-cell homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

4 July 2018

Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

4 July 2018

Effect of experimental treatment on housekeeping gene expression: validation by real-time, quantitative RT-PCR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

4 July 2018

Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

4 July 2018

Serum levels of IL-7 in bone marrow transplant recipients: relationship to clinical characteristics and lymphocyte count

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

4 July 2018

The influence of human immunodeficiency virus-1 on hematopoiesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

4 July 2018

Altered clonogenic capability and stromal cell function characterize bone marrow of HIV-infected subjects with low CD4+ T cell counts despite viral suppression during HAART.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015663

21 January 2018

Increased plasma interleukin-7 level correlates with decreased CD127 and Increased CD132 extracellular expression on T cell subsets in patients with HIV-1 infection.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015663

21 January 2018

Loss of CD127 expression defines an expansion of effector CD8+ T cells in HIV-infected individuals.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015663

21 January 2018

Persistent human immunodeficiency virus-1 antigenaemia affects the expression of interleukin-7Ralpha on central and effector memory CD4+ and CD8+ T cell subsets

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015663

21 January 2018

Liver-related deaths in persons infected with the human immunodeficiency virus: the D:A:D study

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015663

21 January 2018

Human immunodeficiency virus type 1 (HIV-1) induces activation of multiple STATs in CD4+ cells of lymphocyte or monocyte/macrophage lineages

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015663

21 January 2018

Stromal cell-derived factor 1alpha (SDF-1alpha) induces gene-expression of early growth response-1 (Egr-1) and VEGF in human arterial endothelial cells and enhances VEGF induced cell proliferation

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015663

21 January 2018

Enhanced T cell recovery in HIV-1-infected adults through IL-7 treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

30 October 2018

Interleukin-7 receptor expression on CD8(+) T cells is reduced in HIV infection and partially restored with effective antiretroviral therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

30 October 2018

Constitutive activation of STATs upon in vivo human immunodeficiency virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

30 October 2018

Infection of human marrow stroma by human immunodeficiency virus-1 (HIV-1) is both required and sufficient for HIV-1-induced hematopoietic suppression in vitro: demonstration by gene modification of primary human stroma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013120

30 October 2018

Suppression of IL7Rα Transcription by IL-7 and Other Prosurvival Cytokines

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015663

21 January 2018

Predictors of Immunological Failure after Initial Response to Highly Active Antiretroviral Therapy in HIV‐1–Infected Adults: A EuroSIDA Study

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015663

21 January 2018

Editorial Commentary:Immunological Nonresponse to Highly Active Antiretroviral Therapy in HIV‐Infected Subjects: Is the Bone Marrow Impairment Causing CD4 Lymphopenia?

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015663

21 January 2018

Clinical outcome after 4 years follow-up of HIV-seropositive subjects with incomplete virologic or immunologic response to HAART

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015663

21 January 2018

Haemopoietic CD34+ progenitor cells are not infected by HIV-1 in vivo but show impaired clonogenesis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015663

21 January 2018

The correlation between levels of IL-7Ralpha expression and responsiveness to IL-7 is lost in CD4 lymphocytes from HIV-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/21209878

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recovery of haematopoietic abnormalities in HIV-1 infected patients treated with HAART

1 reference

https://pubmed.ncbi.nlm.nih.gov/21209878

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical Outcome of Patients with HIV-1 Infection according to Immunologic and Virologic Response after 6 Months of Highly Active Antiretroviral Therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21209878

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of exogenous interleukin-7 on human thymus function

1 reference

https://pubmed.ncbi.nlm.nih.gov/21209878

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of IL-7Ralpha is associated with CD4 T-cell depletion, high interleukin-7 levels and CD28 down-regulation in HIV infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/21209878

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD127 expression and regulation are altered in the memory CD8 T cells of HIV-infected patients--reversal by highly active anti-retroviral therapy (HAART)

1 reference

https://pubmed.ncbi.nlm.nih.gov/21209878

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory dysfunction of the interleukin-7 receptor in CD4 and CD8 lymphocytes from HIV-infected patients--effects of antiretroviral therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21209878

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-7 receptor expression on CD8 T-cells is downregulated by the HIV Tat protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/21209878

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0015663

1 reference

Europe PubMed Central

29 July 2017

2010PLoSO...515663B

0 references

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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