Positions and numbers of FKS mutations in Candida albicans selectively influence in vitro and in vivo susceptibilities to echinocandin treatment. (Q33798606)

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English	Positions and numbers of FKS mutations in Candida albicans selectively influence in vitro and in vivo susceptibilities to echinocandin treatment.	scientific article

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14 March 2020

Positions and numbers of FKS mutations in Candida albicans selectively influence in vitro and in vivo susceptibilities to echinocandin treatment (English)

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14 March 2020

Candida albicans

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Michael Tscherner

2

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14 March 2020

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14 March 2020

Maiken C Arendrup

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14 March 2020

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M Lackner

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14 March 2020

M Schaller

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14 March 2020

C Mair

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14 March 2020

B Sartori

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14 March 2020

F Istel

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14 March 2020

C Lass-Flörl

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14 March 2020

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14 April 2014

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14 March 2020

Antimicrobial Agents and Chemotherapy

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14 March 2020

58

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14 March 2020

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14 March 2020

3626-3635

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14 March 2020

Candida and candidaemia. Susceptibility and epidemiology

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4 July 2018

Invasive candidiasis as a cause of sepsis in the critically ill patient

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4 July 2018

Interlaboratory variability of Caspofungin MICs for Candida spp. Using CLSI and EUCAST methods: should the clinical laboratory be testing this agent?

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4 July 2018

Rapid emergence of echinocandin resistance in Candida glabrata resulting in clinical and microbiologic failure.

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4 July 2018

Echinocandin and triazole antifungal susceptibility profiles for clinical opportunistic yeast and mold isolates collected from 2010 to 2011: application of new CLSI clinical breakpoints and epidemiological cutoff values for characterization of geogr

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4 July 2018

Stepwise development of a homozygous S80P substitution in Fks1p, conferring echinocandin resistance in Candida tropicalis.

1 reference

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4 July 2018

Fks1 and Fks2 are functionally redundant but differentially regulated in Candida glabrata: implications for echinocandin resistance

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4 July 2018

Caspofungin Etest susceptibility testing of Candida species: risk of misclassification of susceptible isolates of C. glabrata and C. krusei when adopting the revised CLSI caspofungin breakpoints

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4 July 2018

Differential in vivo activities of anidulafungin, caspofungin, and micafungin against Candida glabrata isolates with and without FKS resistance mutations

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4 July 2018

Resistance to echinocandins comes at a cost: the impact of FKS1 hotspot mutations on Candida albicans fitness and virulence

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4 July 2018

Candida spp. with acquired echinocandin resistance, France, 2004-2010.

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4 July 2018

Antifungal drug resistance: mechanisms, epidemiology, and consequences for treatment

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4 July 2018

Elevated cell wall chitin in Candida albicans confers echinocandin resistance in vivo

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4 July 2018

Epidemiological characteristics of Candida species colonizing oral and rectal sites of Jordanian infants

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4 July 2018

Molecular typing of Candida albicans isolates from patients and health care workers in a neonatal intensive care unit

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4 July 2018

Fitness and virulence costs of Candida albicans FKS1 hot spot mutations associated with echinocandin resistance.

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4 July 2018

Disseminated Candidiasis caused by Candida albicans with amino acid substitutions in Fks1 at position Ser645 cannot be successfully treated with micafungin

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4 July 2018

Candida bloodstream infections: comparison of species distributions and antifungal resistance patterns in community-onset and nosocomial isolates in the SENTRY Antimicrobial Surveillance Program, 2008-2009

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4 July 2018

Clinically significant micafungin resistance in Candida albicans involves modification of a glucan synthase catalytic subunit GSC1 (FKS1) allele followed by loss of heterozygosity.

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4 July 2018

Antibiotic resistance and its cost: is it possible to reverse resistance?

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4 July 2018

Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin

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4 July 2018

Evolution of pathogenicity and sexual reproduction in eight Candida genomes

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4 July 2018

Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America.

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4 July 2018

Correlating echinocandin MIC and kinetic inhibition of fks1 mutant glucan synthases for Candida albicans: implications for interpretive breakpoints

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4 July 2018

Resistance to echinocandin-class antifungal drugs

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4 July 2018

Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates

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4 July 2018

The Candida albicans Cdr2p ATP-binding cassette (ABC) transporter confers resistance to caspofungin.

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4 July 2018

EUCAST technical note on Candida and micafungin, anidulafungin and fluconazole

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Fungal infection in patients after liver transplantation in years 2003 to 2012.

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ESCMID* guideline for the diagnosis and management of Candida diseases 2012: adults with haematological malignancies and after haematopoietic stem cell transplantation (HCT).

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The SAT1 flipper, an optimized tool for gene disruption in Candida albicans

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Isolation of the Candida albicans gene for orotidine-5'-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations

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Development and verification of fingerprinting probes for Candida glabrata

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10.1128/AAC.00123-14

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14 March 2020

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14 March 2020

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