Tolerance after liver transplantation: does it exist and can immunosuppression be withdrawn? (Q33799265)

29 July 2017

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title

Tolerance after liver transplantation: does it exist and can immunosuppression be withdrawn? (English)

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29 July 2017

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liver transplantation

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Riordan SM

1

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PubMed ID

10604587

29 July 2017

Williams R

series ordinal

2

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29 July 2017

1 December 1999

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29 July 2017

Journal of Hepatology

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29 July 2017

31

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29 July 2017

6

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29 July 2017

1106-1119

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Quantitative Studies on Tissue Transplantation Immunity. II. The Origin, Strength and Duration of Actively and Adoptively Acquired Immunity

29 July 2017

1 reference

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The cellular basis of allograft rejection in vivo. II. The nature of memory cells mediating second set heart graft rejection

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Induction of immunological tolerance by porcine liver allografts

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7 January 2021

Fully allogeneic liver grafting in rats induces a state of systemic nonreactivity to donor transplantation antigens

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7 January 2021

Specific transplantation tolerance induced by spontaneously tolerated liver allograft in inbred strains of rats

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7 January 2021

Reversal of transplantation immunity by liver grafting

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7 January 2021

High-dose/activation-associated tolerance: a mechanism for allograft tolerance

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7 January 2021

Antigen-specific immunosuppression induced by liver transplantation in the rat

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7 January 2021

Evolution of liver transplantation

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7 January 2021

Organ graft tolerance: the liver effect

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7 January 2021

Cell migration and chimerism after whole-organ transplantation: the basis of graft acceptance

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7 January 2021

Weaning of immunosuppression in long-term liver transplant recipients

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7 January 2021

Weaning of immunosuppression in liver transplant recipients

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7 January 2021

Cyclosporine withdrawal for nephrotoxicity in liver transplant recipients does not result in sustained improvement in kidney function and causes cellular and ductopenic rejection

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7 January 2021

Cyclosporine A reduction and withdrawal in liver transplantation: a risk-benefit analysis

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7 January 2021

Defining the outcome of immunosuppression withdrawal after liver transplantation

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7 January 2021

Tolerance and latent cellular rejection in long-term liver transplant recipients

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7 January 2021

CD95L confers immune priviledge to liver grafts which are spontaneously accepted.

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Kinetics of intragraft cytokine expression, cellular infiltration, and cell death in rejection of renal allografts compared with acceptance of liver allografts in a rat model: early activation and apoptosis is associated with liver graft acceptance.

1 reference

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7 January 2021

Donor pretreatment with Flt-3 ligand augments antidonor cytotoxic T lymphocyte, natural killer, and lymphokine-activated killer cell activities within liver allografts and alters the pattern of intragraft apoptotic activity

1 reference

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7 January 2021

Spontaneous acceptance of liver allografts in the rat. Analysis of the immune response

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7 January 2021

Apoptosis of graft-infiltrating cytotoxic T cells: a mechanism underlying "split tolerance" in mouse liver transplantation

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7 January 2021

Apoptosis as an instrument for immune regulation: study on a liver/small bowel tolerant rat model

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7 January 2021

Cells mediating allograft rejection

1 reference

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7 January 2021

Specific unresponsiveness in rats with prolonged cardiac allograft survival after treatment with cyclosporine. III. Further characterization of the CD4+ suppressor cell and its mechanisms of action

1 reference

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7 January 2021

Immunosuppressive activity of serum from liver-grafted rats. Passive enhancement of fully allogeneic heart grafts and induction of systemic tolerance

1 reference

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7 January 2021

Peripheral tolerance to alloantigen results from altered regulation of the interleukin 2 pathway

1 reference

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7 January 2021

Secreted donor-MHC class I antigen prolongs liver allograft survival and inhibits recipient anti-donor cytotoxic T lymphocyte responses

1 reference

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7 January 2021

Donor-specific hyporeactivity after liver transplantation: prominent decreases in donor-specific cytotoxic T lymphocyte precursor frequencies independent of changes in helper T lymphocyte precursor frequencies or suppressor cell activity

1 reference

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7 January 2021

Analysis of T cell responses in liver allograft recipients. Evidence for deletion of donor-specific cytotoxic T cells in the peripheral circulation

1 reference

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7 January 2021

PERSISTENCE OF DONOR-REACTIVE CD4+ T CELLS IN LIVER AND SPLEEN OF RATS TOLERANT TO A LIVER ALLOGRAFT1

1 reference

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7 January 2021

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones

1 reference

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7 January 2021

The essential roles of parenchymal tissues and passenger leukocytes in the tolerance induced by liver grafting in rats

1 reference

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7 January 2021

Prolongation of liver allograft survival by donor-specific soluble transplantation antigens and antigen-antibody complexes

1 reference

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7 January 2021

In vivo immunogenicity of purified allogeneic hepatocytes in a murine hepatocyte transplant model

1 reference

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7 January 2021

Tolerance to rat liver allografts: IV. Acceptance depends on the quantity of donor tissue and on donor leukocytes

1 reference

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7 January 2021

The role of T suppressor cells in the maintenance of spontaneously accepted orthotopic rat liver allografts

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7 January 2021

Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells.

1 reference

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7 January 2021

MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and Responsiveness

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7 January 2021

Current concepts: immunology. Transplantation immunology

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7 January 2021

Identification in rat liver and serum of water-soluble class I MHC molecules possibly homologous to the murine Q10 gene product

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7 January 2021

Anti HL-A2 Inhibitor in Normal Human Serum

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7 January 2021

Biochemical analysis of a 40,000 mol. wt mouse serum protein which binds β2-microglobulin and has serological cross-reactivity with H-2 antigens

1 reference

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7 January 2021

Quantitative and biochemical characterization of soluble HLA class I antigens shed by cultured human cells

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7 January 2021

Secretion of HLA-A and -B antigens via an alternative RNA splicing pathway

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7 January 2021

Bulk purification of a naturally occurring soluble form of RT1-A class I major histocompatibility complex antigens from DA rat liver, and studies of specific immunosuppression

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7 January 2021

Class I transplantation antigens in solution in body fluids and in the urine. Individuality signals to the environment

1 reference

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7 January 2021

The use of antigenic tissue extracts to weaken the immunological reaction against skin homografts in mice

1 reference

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7 January 2021

Soluble HLA antigens in the circulation of liver graft recipients

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7 January 2021

Biochemical and immunological evaluation of donor-specific soluble HLA in the circulation of liver transplant recipients

1 reference

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7 January 2021

SEROLOGIC ALLOGENEIC CHIMERISM

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7 January 2021

Soluble MHC class I antigens (sHLA) and anti-HLA antibodies in heart and kidney allograft recipients

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980326-2

7 January 2021

Specific suppression of allograft rejection by soluble class I antigen and complexes with monoclonal antibody

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https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980326-2

7 January 2021

Impact of donor MHC class I or class II antigen deficiency on first- and second-set rejection of mouse heart or liver allografts

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980326-2

7 January 2021

Soluble HLA class I molecules induce apoptosis in alloreactive cytotoxic T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980326-2

7 January 2021

Molecular events in the induction of a nonresponsive state in interleukin 2-producing helper T-lymphocyte clones

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7 January 2021

Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway

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7 January 2021

Alloreactive immune responses of transgenic mice expressing a foreign transplantation antigen in a soluble form

1 reference

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7 January 2021

Resident human hepatitis lymphocytes are phenotypically different from circulating lymphocytes

1 reference

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7 January 2021

Isolation, phenotype, and allostimulatory activity of mouse liver dendritic cells

1 reference

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7 January 2021

Deletion of spontaneous rat liver allograft acceptance by donor irradiation

1 reference

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7 January 2021

Rejection of spontaneously accepted rat liver allografts with recipientinterleukin-2 treatment or donor irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980326-2

7 January 2021

Role of reconstituted passenger leukocytes on the induction of tolerance in rat liver transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980326-2

7 January 2021

Persistence of donor lymphocytes in liver allograft recipients

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980326-2

7 January 2021

Cell migration, chimerism, and graft acceptance

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980326-2

7 January 2021

Microchimerism and rejection in clinical transplantation

1 reference

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7 January 2021

Peripheral blood chimerism following human liver transplantation

1 reference

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7 January 2021

Donor dendritic cells after liver and heart allotransplantation under short-term immunosuppression

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980326-2

7 January 2021

Patterns of donor-type microchimerism after heart transplantation

1 reference

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7 January 2021

Donor cell chimerism permitted by immunosuppressive drugs: a new view of organ transplantation

1 reference

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7 January 2021

Evidence that pediatric liver transplant recipients may undergo late rejection episodes in spite of donor-specific microchimerism

1 reference

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7 January 2021

Peripheral blood microchimerism in human liver and renal transplant recipients: rejection despite donor-specific chimerism

1 reference

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7 January 2021

Multilineage hematopoietic reconstitution of supralethally irradiated rats by syngeneic whole organ transplantation. With oarticular reference to the liver

1 reference

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7 January 2021

Presence of hematopoietic stem cells in the adult liver

1 reference

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7 January 2021

Activation of Transplant Immunity: Effect of Donor Leukocytes on Thyroid Allograft Rejection

1 reference

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7 January 2021

Immunobiology of tissue transplantation: a return to the passenger leukocyte concept

1 reference

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7 January 2021

Restoration of immunogenicity to passenger cell-depleted kidney allografts by the addition of donor strain dendritic cells

1 reference

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7 January 2021

Rapid and long-term changes to host cytotoxic T lymphocyte precursors reactive to donor antigens caused by intravenous injection of histoincompatible lymphocytes

1 reference

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7 January 2021

Programmed Cell Death of T Cells Signaled by the T Cell Receptor and the α 3 Domain of Class I MH

1 reference

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7 January 2021

Blocking of the B7-CD28 pathway increases the capacity of FasL+ (CD95L+) dendritic cells to kill alloactivated T cells.

1 reference

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7 January 2021

The lost chord: microchimerism and allograft survival

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980326-2

7 January 2021

Chimerism and transplantation tolerance: cause and effect

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980326-2

7 January 2021

Is microchimerism needed for allograft tolerance?

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980326-2

7 January 2021

Evidence that the continued presence of the organ graft and not peripheral donor microchimerism is essential for maintenance of tolerance to alloantigen in vivo in anti-CD4 treated recipients

1 reference

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980326-2

7 January 2021

Donor-type microchimerism associated with graft rejection eight years after liver transplantation

1 reference

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7 January 2021

High-dose donor bone marrow infusions to enhance allograft survival: the effect of timing

1 reference

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7 January 2021

Microchimerism, dendritic cell progenitors and transplantation tolerance

1 reference

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7 January 2021

The dendritic cell system and its role in immunogenicity

1 reference

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7 January 2021

Costimulatory molecule-deficient dendritic cell progenitors (MHC class II+, CD80dim, CD86-) prolong cardiac allograft survival in nonimmunosuppressed recipients

1 reference

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0168-8278%2899%2980326-2

1 reference

7 January 2021

Acute liver allograft rejection in the rat. An analysis of the immune response

1 reference

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7 January 2021

T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis

1 reference

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7 January 2021

Administration of exogenous interleukin-2 abrogates spontaneous rat liver allograft acceptance but does not affect long-term established graft survival

1 reference

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7 January 2021

Tacrolimus-induced apoptosis and its prevention by interleukins in mitogen-activated human peripheral-blood mononuclear cells

1 reference

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7 January 2021

FK506 augments activation-induced programmed cell death of T lymphocytes in vivo

1 reference

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7 January 2021

Apoptosis, graft rejection, and transplantation tolerance

1 reference

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7 January 2021

Prednisone withdrawal late after adult liver transplantation reduces diabetes, hypertension, and hypercholesterolemia without causing graft loss.

1 reference

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7 January 2021

CD4-targeted therapy and CD28-B7 costimulatory blockage may independently induce tolerance in sensitized allograft recipients.

1 reference

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7 January 2021

Anti-CD4 therapy in combined heart-kidney, heart-liver, and heart-small bowel allotransplants in high-responder rats

1 reference

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7 January 2021

Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg

1 reference

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7 January 2021

Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion

1 reference

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7 January 2021

Recipient pretreatment with mammalian IL-10 prolongs mouse cardiac allograft survival by inhibition of anti-donor T cell responses

1 reference

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7 January 2021

10.1016/S0168-8278(99)80326-2

Identifiers

DOI

1 reference

29 July 2017

1 reference

PubMed ID

10604587