Can antigen-specific regulatory T cells protect against graft versus host disease and spare anti-malignancy alloresponse? (Q33800533)

29 July 2017

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title

Can antigen-specific regulatory T cells protect against graft versus host disease and spare anti-malignancy alloresponse? (English)

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29 July 2017

Joseph Pidala

1

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29 July 2017

Claudio Anasetti

series ordinal

2

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29 July 2017

publication date

16 December 2009

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29 July 2017

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29 July 2017

volume

95

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29 July 2017

issue

4

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29 July 2017

page(s)

660-665

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Foxp3+ regulatory T cells: differentiation, specification, subphenotypes

29 July 2017

cites work

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Depletion of CD4+CD25+ regulatory T cells enhances interleukin-2-induced antitumor immunity in a mouse model of colon adenocarcinoma

28 July 2018

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Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice

28 July 2018

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Role of naturally arising regulatory T cells in hematopoietic cell transplantation

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

28 July 2018

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Suppressor activity and potency among regulatory T cells is discriminated by functionally active CD44

28 July 2018

1 reference

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Reduced frequency of FOXP3+ CD4+CD25+ regulatory T cells in patients with chronic graft-versus-host disease

28 July 2018

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Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes

28 July 2018

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In vivo elimination of CD25+ regulatory T cells leads to tumor rejection of B16F10 melanoma, when combined with interleukin-12 gene transfer

28 July 2018

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Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells

28 July 2018

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Large-scale in vitro expansion of polyclonal human CD4(+)CD25high regulatory T cells.

28 July 2018

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Regulatory T cells generated ex vivo as an approach for the therapy of autoimmune disease

28 July 2018

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In vitro-expanded human CD4(+)CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures

28 July 2018

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Human CD(4+)CD(25+) regulatory T cells and infectious tolerance

28 July 2018

1 reference

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Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia

28 July 2018

1 reference

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Post-hematopoietic cell transplantation control of graft-versus-host disease by donor CD425 T cells to allow an effective graft-versus-leukemia response

28 July 2018

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Natural versus adaptive regulatory T cells

28 July 2018

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Hematopoiesis-restricted minor histocompatibility antigens HA-1- or HA-2-specific T cells can induce complete remissions of relapsed leukemia

28 July 2018

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CD4(+)CD25(+) immunoregulatory T Cells: new therapeutics for graft-versus-host disease

28 July 2018

1 reference

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Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation

28 July 2018

1 reference

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Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells

28 July 2018

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The primacy of the gastrointestinal tract as a target organ of acute graft-versus-host disease: rationale for the use of cytokine shields in allogeneic bone marrow transplantation

28 July 2018

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Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific

28 July 2018

1 reference

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Phase III study comparing methotrexate and tacrolimus (prograf, FK506) with methotrexate and cyclosporine for graft-versus-host disease prophylaxis after HLA-identical sibling bone marrow transplantation

28 July 2018

1 reference

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Human minor histocompatibility antigens

28 July 2018

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Human H-Y: a male-specific histocompatibility antigen derived from the SMCY protein

28 July 2018

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Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

28 July 2018

1 reference

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Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease

28 July 2018

1 reference

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Treatment of moderate/severe acute graft-versus-host disease after allogeneic bone marrow transplantation: an analysis of clinical risk features and outcome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857197

Graft-versus-leukemia reactions after bone marrow transplantation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857197

OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: prevention by the OX-22low subset

28 July 2018

1 reference

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A retrospective analysis of therapy for acute graft-versus-host disease: initial treatment

28 July 2018

1 reference

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Cytokine dysregulation and acute graft-versus-host disease

28 July 2018

1 reference

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Human T regulatory cell therapy: take a billion or so and call me in the morning

28 July 2018

1 reference

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Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor

30 October 2018

1 reference

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Calcineurin inhibitor-free GVHD prophylaxis with sirolimus, mycophenolate mofetil and ATG in Allo-SCT for leukemia patients with high relapse risk: an observational cohort study

30 October 2018

1 reference

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Conferring indirect allospecificity on CD4+CD25+ Tregs by TCR gene transfer favors transplantation tolerance in mice.

30 October 2018

1 reference

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Adoptive transfer of transplantation tolerance mediated by CD4+CD25+ and CD8+CD28- regulatory T cells induced by anti-donor-specific T-cell vaccination

30 October 2018

1 reference

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Treg depletion inhibits efficacy of cancer immunotherapy: implications for clinical trials

30 October 2018

1 reference

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Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients

30 October 2018

1 reference

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Altered activation of AKT is required for the suppressive function of human CD4+CD25+ T regulatory cells

30 October 2018

1 reference

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Only the CD45RA+ subpopulation of CD4+CD25high T cells gives rise to homogeneous regulatory T-cell lines upon in vitro expansion.

30 October 2018

1 reference

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T regulatory cells as an immunotherapy for transplantation

30 October 2018

1 reference

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Inhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 production

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857197

CD25+ regulatory T cell depletion augments immunotherapy of micrometastases by an IL-21-secreting cellular vaccine

30 October 2018

1 reference

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Rapamycin, and not cyclosporin A, preserves the highly suppressive CD27+ subset of human CD4+CD25+ regulatory T cells

30 October 2018

1 reference

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Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from nonobese diabetic mice

30 October 2018

1 reference

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Antigen-dependent suppression of alloresponses by Foxp3-induced regulatory T cells in transplantation.

30 October 2018

1 reference

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CD27/CFSE-based ex vivo selection of highly suppressive alloantigen-specific human regulatory T cells.

30 October 2018

1 reference

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Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857197

Induction of antigen-specific immunologic tolerance by in vivo and in vitro antigen-specific expansion of naturally arising Foxp3+CD25+CD4+ regulatory T cells

30 October 2018

1 reference

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CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857197

In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes

30 October 2018

1 reference

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Association of Foxp3 regulatory gene expression with graft-versus-host disease

30 October 2018

1 reference

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Transplantation of cultured islets from two-layer preserved pancreases in type 1 diabetes with anti-CD3 antibody

30 October 2018

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Acceleration of apoptosis in CD4+CD8+ thymocytes by rapamycin accompanied by increased CD4+CD25+ T cells in the periphery

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857197

CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857197

30 October 2018

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12 December 2020

Phase 3 study comparing methotrexate and tacrolimus with methotrexate and cyclosporine for prophylaxis of acute graft-versus-host disease after marrow transplantation from unrelated donors

1 reference

12 December 2020

The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality

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12 December 2020

Generation and expansion of human CD4+ CD25+ regulatory T cells with indirect allospecificity: Potential reagents to promote donor-specific transplantation tolerance

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12 December 2020

In vitro-expanded donor alloantigen-specific CD4+CD25+ regulatory T cells promote experimental transplantation tolerance

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12 December 2020

Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance

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12 December 2020

Marrow transplantation for the treatment of chronic myelogenous leukemia

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12 December 2020

Tissue distribution of human minor histocompatibility antigens. Ubiquitous versus restricted tissue distribution indicates heterogeneity among human cytotoxic T lymphocyte-defined non-MHC antigens

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12 December 2020

Autologous or allogeneic bone marrow transplantation compared with intensive chemotherapy in acute myelogenous leukemia. European Organization for Research and Treatment of Cancer (EORTC) and the Gruppo Italiano Malattie Ematologiche Maligne dell'Ad

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12 December 2020

Feasibility of immunotherapy of relapsed leukemia with ex vivo-generated cytotoxic T lymphocytes specific for hematopoietic system-restricted minor histocompatibility antigens

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12 December 2020

Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD

1 reference

12 December 2020

10.3324/HAEMATOL.2009.015818

Identifiers

DOI

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29 July 2017

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29 July 2017

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