Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of hematopoietic cells in zebrafish. (Q33806096)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20197555%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of hematopoietic cells in zebrafish (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20197555%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

0 references

1

1 reference

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19 January 2020

Brunangelo Falini

6

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19 January 2020

author name string

Elspeth M Payne

2

1 reference

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19 January 2020

Clemens Grabher

3

1 reference

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19 January 2020

Jeong-Soo Lee

4

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19 January 2020

Adam B Johnston

5

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19 January 2020

John P Kanki

7

1 reference

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19 January 2020

A Thomas Look

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20197555%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

language of work or name

English

0 references

publication date

2 March 2010

1 reference

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19 January 2020

number of pages

12

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based on heuristic

inferred from page(s)

published in

Blood

1 reference

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19 January 2020

volume

115

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19 January 2020

issue

16

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19 January 2020

page(s)

3329-3340

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describes a project that uses

19 January 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2858496/fullTextXML

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inferred from PubMed Central ID database lookup

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Definitive hematopoiesis initiates through a committed erythromyeloid progenitor in the zebrafish embryo

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Born to be exported: COOH-terminal nuclear export signals of different strength ensure cytoplasmic accumulation of nucleophosmin leukemic mutants

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The zebrafish lysozyme C promoter drives myeloid-specific expression in transgenic fish

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4 July 2018

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Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML.

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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GATA-1 expression pattern can be recapitulated in living transgenic zebrafish using GFP reporter gene.

4 July 2018

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Intraembryonic hematopoietic cell migration during vertebrate development

4 July 2018

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In human genome, generation of a nuclear export signal through duplication appears unique to nucleophosmin (NPM1) mutations and is restricted to AML.

4 July 2018

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The leukemia-associated cytoplasmic nucleophosmin mutant is an oncogene with paradoxical functions: Arf inactivation and induction of cellular senescence.

30 October 2018

1 reference

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Regulation of the lmo2 promoter during hematopoietic and vascular development in zebrafish.

30 October 2018

1 reference

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The pu.1 promoter drives myeloid gene expression in zebrafish.

30 October 2018

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Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants

30 October 2018

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Myc-induced T cell leukemia in transgenic zebrafish.

30 October 2018

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Myelopoiesis in the zebrafish, Danio rerio.

30 October 2018

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30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20197555

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2009-02-207225

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20197555%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20197555%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference