Biopharmaceutical and pharmacokinetic characterization of matrine as determined by a sensitive and robust UPLC-MS/MS method (Q33809059)

29 July 2017

title

Biopharmaceutical and pharmacokinetic characterization of matrine as determined by a sensitive and robust UPLC-MS/MS method (English)

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29 July 2017

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Zhen Yang

1

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29 July 2017

Song Gao

2

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29 July 2017

Taijun Yin

3

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29 July 2017

Kaustubh H Kulkarni

4

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29 July 2017

Yang Teng

5

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29 July 2017

Ming You

6

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29 July 2017

Ming Hu

7

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29 July 2017

publication date

26 November 2009

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Journal of Pharmaceutical and Biomedical Analysis

29 July 2017

published in

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29 July 2017

volume

51

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29 July 2017

issue

5

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29 July 2017

page(s)

1120-1127

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Matrine induces apoptosis in gastric carcinoma cells via alteration of Fas/FasL and activation of caspase-3.

29 July 2017

cites work

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Physiologically based pharmacokinetics of matrine in the rat after oral administration of pure chemical and ACAPHA

4 July 2018

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Simultaneous determination and pharmacokinetic study of oxymatrine and matrine in beagle dog plasma after oral administration of Kushen formula granule, oxymatrine and matrine by LC-MS/MS.

4 July 2018

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Cancer chemopreventive activity of a mixture of Chinese herbs (antitumor B) in mouse lung tumor models

4 July 2018

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Absorption and metabolism of flavonoids in the caco-2 cell culture model and a perused rat intestinal model

4 July 2018

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Membrane permeability parameters for some amino acids and beta-lactam antibiotics: application of the boundary layer approach.

4 July 2018

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Estimating human oral fraction dose absorbed: a correlation using rat intestinal membrane permeability for passive and carrier-mediated compounds.

4 July 2018

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Matrine determination and pharmacokinetics in human plasma using LC/MS/MS.

4 July 2018

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Hepatoprotective and anti-hepatocarcinogenic effects of glycyrrhizin and matrine.

30 October 2018

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Disposition of flavonoids via enteric recycling: UDP-glucuronosyltransferase (UGT) 1As deficiency in Gunn rats is compensated by increases in UGT2Bs activities

30 October 2018

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Determination of matrine in rat plasma by high-performance liquid chromatography and its application to pharmacokinetic studies

30 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859310

Pharmacokinetic study of matrine, oxymatrine and oxysophocarpine in rat plasma after oral administration of Sophora flavescens Ait. extract by liquid chromatography tandem mass spectrometry

30 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859310

Determination and pharmacokinetic study of oxymatrine and its metabolite matrine in human plasma by liquid chromatography tandem mass spectrometry

30 October 2018

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Potential beneficial metabolic interactions between tamoxifen and isoflavones via cytochrome P450-mediated pathways in female rat liver microsomes

30 October 2018

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Quantitative analysis of eight testosterone metabolites using column switching and liquid chromatography/tandem mass spectrometry

30 October 2018

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Disposition of flavonoids via enteric recycling: enzyme-transporter coupling affects metabolism of biochanin A and formononetin and excretion of their phase II conjugates

30 October 2018

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Metabolism of flavonoids via enteric recycling: mechanistic studies of disposition of apigenin in the Caco-2 cell culture model

30 October 2018

1 reference

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Identification of CYP1A2 as the main isoform for the phase I hydroxylated metabolism of genistein and a prodrug converting enzyme of methylated isoflavones

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859310

Determination of absorption characteristics of AG337, a novel thymidylate synthase inhibitor, using a perfused rat intestinal model

30 October 2018

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12 December 2020

Mechanism and kinetics of transcellular transport of a new beta-lactam antibiotic loracarbef across an intestinal epithelial membrane model system (Caco-2)

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12 December 2020

The Caco-2 cell monolayers as an intestinal metabolism model: metabolism of dipeptide Phe-Pro

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12 December 2020

Mechanisms responsible for poor oral bioavailability of paeoniflorin: Role of intestinal disposition and interactions with sinomenine

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12 December 2020

[Pharmacokinetics of matrine in healthy volunteers]

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12 December 2020

Molecular mechanism of matrine-induced apoptosis in leukemia K562 cells

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12 December 2020

10.1016/J.JPBA.2009.11.020

Identifiers

DOI

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29 July 2017

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29 July 2017

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