Human immunodeficiency virus-specific circulating CD8 T lymphocytes have down-modulated CD3zeta and CD28, key signaling molecules for T-cell activation (Q33809451)

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English	Human immunodeficiency virus-specific circulating CD8 T lymphocytes have down-modulated CD3zeta and CD28, key signaling molecules for T-cell activation	scientific article

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

Human immunodeficiency virus-specific circulating CD8 T lymphocytes have down-modulated CD3zeta and CD28, key signaling molecules for T-cell activation (English)

1 reference

Europe PubMed Central

29 July 2017

author name string

L A Trimble

1

1 reference

Europe PubMed Central

29 July 2017

P Shankar

2

1 reference

Europe PubMed Central

29 July 2017

M Patterson

3

1 reference

Europe PubMed Central

29 July 2017

J P Daily

4

1 reference

Europe PubMed Central

29 July 2017

J Lieberman

5

1 reference

Europe PubMed Central

29 July 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 August 2000

1 reference

Europe PubMed Central

29 July 2017

Journal of Virology

1 reference

Europe PubMed Central

29 July 2017

74

1 reference

Europe PubMed Central

29 July 2017

16

1 reference

Europe PubMed Central

29 July 2017

7320-7330

1 reference

Europe PubMed Central

29 July 2017

A transgenic mouse model to analyze CD8(+) effector T cell differentiation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

Viral-specific cytotoxic T lymphocytes lyse human immunodeficiency virus-infected primary T lymphocytes by the granule exocytosis pathway

1 reference

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4 July 2018

Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients

1 reference

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4 July 2018

Viral immune evasion due to persistence of activated T cells without effector function

1 reference

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4 July 2018

The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses

1 reference

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4 July 2018

Decay kinetics of human immunodeficiency virus-specific effector cytotoxic T lymphocytes after combination antiretroviral therapy.

1 reference

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4 July 2018

Effective lysis of HIV-1-infected primary CD4+ T cells by a cytotoxic T-lymphocyte clone directed against a novel A2-restricted reverse-transcriptase epitope

1 reference

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4 July 2018

Single-cell analysis of lymphokine imbalance in asymptomatic HIV-1 infection: evidence for a major alteration within the CD8+ T cell subset.

1 reference

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4 July 2018

Viral strategies of immune evasion

1 reference

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4 July 2018

Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta chain

1 reference

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4 July 2018

Dynamics of fine T-cell subsets during HIV disease and after thymic ablation by mediastinal irradiation

1 reference

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4 July 2018

Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia

1 reference

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4 July 2018

CD28 costimulation increases CD8+ cell suppression of HIV replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

Phenotypic and functional separation of memory and effector human CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

Determination of antigen-specific memory/effector CD4+ T cell frequencies by flow cytometry: evidence for a novel, antigen-specific homeostatic mechanism in HIV-associated immunodeficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

CD8+ cells and not CD4+ T cells are hyporesponsive to CD28- and CD40L-mediated activation in HIV-infected subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

Regulation of CD28 costimulation in human CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

HIV infection--induced posttranslational modification of T cell signaling molecules associated with disease progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

Phenotypic analysis of antigen-specific T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

Delayed virus-specific CD8+ cytotoxic T lymphocyte activity in an HIV-infected individual with high CD4+ cell counts: correlations with various parameters of disease progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

Signal transduction by lymphocyte antigen receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

Expansion of a CD8+CD28- cell population in the blood and lung of HIV-positive patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

Direct and indirect mechanisms mediating apoptosis during HIV infection: contribution to in vivo CD4 T cell depletion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

Human immunodeficiency virus Tat induces functional unresponsiveness in T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

Ex vivo expansion of HIV type 1-specific cytolytic T cells from HIV type 1-seropositive subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

CD8 naive T cell counts decrease progressively in HIV-infected adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

Persistent high frequency of human immunodeficiency virus-specific cytotoxic T cells in peripheral blood of infected donors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

Increased cytolytic T lymphocyte activity and decreased B7 responsiveness are associated with CD28 down-regulation on CD8+ T cells from HIV-infected subjects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

Naturally processed viral peptides recognized by cytotoxic T lymphocytes on cells chronically infected by human immunodeficiency virus type 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

Evidence for circulating activated cytotoxic T cells in HIV-infected subjects before the onset of opportunistic infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

Cytotoxic T lymphocytes from HIV-1 seropositive individuals recognize immunodominant epitopes in Gp160 and reverse transcriptase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

4 July 2018

CD3zeta and CD28 down-modulation on CD8 T cells during viral infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

30 October 2018

Treatment of human immunodeficiency virus infection with hydroxyurea, didanosine, and a protease inhibitor before seroconversion is associated with normalized immune parameters and limited viral reservoir

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

30 October 2018

Decreased expression of zeta molecules by T lymphocytes is correlated with disease progression in human immunodeficiency virus-infected persons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

30 October 2018

Human CD28-CD8+ T cells contain greatly expanded functional virus-specific memory CTL clones.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

30 October 2018

HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

30 October 2018

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

30 October 2018

Circulating CD8 T lymphocytes in human immunodeficiency virus-infected individuals have impaired function and downmodulate CD3 zeta, the signaling chain of the T-cell receptor complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

30 October 2018

Circulating HIV-specific CD8+ cytotoxic T cells express CD38 and HLA-DR antigens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

30 October 2018

Absence of recoverable infectious virus and unique immune responses in an asymptomatic HIV+ long-term survivor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

30 October 2018

Massive activation of immune cells with an intact T cell repertoire in acute human immunodeficiency virus syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

30 October 2018

Increases in CD4 T lymphocytes with intermittent courses of interleukin-2 in patients with human immunodeficiency virus infection. A preliminary study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

30 October 2018

HIV-1 gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112252

30 October 2018

Expansion of T cells negative for CD28 expression in HIV infection. Relation to activation markers and cell adhesion molecules, and correlation with prognostic markers

1 reference

https://pubmed.ncbi.nlm.nih.gov/10906185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydroxyurea and didanosine long-term treatment prevents HIV breakthrough and normalizes immune parameters

1 reference

https://pubmed.ncbi.nlm.nih.gov/10906185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in expression and function of signal-transducing proteins in tumor-associated T and natural killer cells in patients with ovarian carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10906185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of HIV-1-specific T-helper cells in acute and chronic infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/10906185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unusually high frequencies of HIV-specific cytotoxic T lymphocytes in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/10906185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoregulation in cancer-bearing hosts. Down-regulation of gene expression and cytotoxic function in CD8+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10906185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10906185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of HIV-1 Tat induced inhibition of antigen-specific T cell responsiveness

1 reference

https://pubmed.ncbi.nlm.nih.gov/10906185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of T cell subsets involved in the production of IFN-gamma in asymptomatic HIV-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/10906185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective TCR-mediated signaling in synovial T cells in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10906185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 rebound during interruption of highly active antiretroviral therapy has no deleterious effect on reinitiated treatment. Comet Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/10906185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perforin is not co-expressed with granzyme A within cytotoxic granules in CD8 T lymphocytes present in lymphoid tissue during chronic HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/10906185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of T-cell receptor zeta chain and p56lck in T-cells infiltrating human renal cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10906185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anergy and apoptosis in CD8+ T cells from HIV-infected persons

1 reference

https://pubmed.ncbi.nlm.nih.gov/10906185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphocyte activation in HIV-1 infection. II. Functional defects of CD28- T cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10906185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between disease activity and T-cell CD3 zeta chain expression in a B-cell lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10906185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in the signal-transducing molecules of T cells and NK cells in colorectal tumor-infiltrating, gut mucosal and peripheral lymphocytes: correlation with the stage of the disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10906185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response

1 reference

https://pubmed.ncbi.nlm.nih.gov/10906185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cells from patients with Hodgkin's disease have a defective T-cell receptor zeta chain expression that is reversible by T-cell stimulation with CD3 and CD28

1 reference

https://pubmed.ncbi.nlm.nih.gov/10906185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.74.16.7320-7330.2000

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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