The specificity of proteasomes: impact on MHC class I processing and presentation of antigens (Q33815363)

29 July 2017

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title

The specificity of proteasomes: impact on MHC class I processing and presentation of antigens (English)

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29 July 2017

Niedermann G

1

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29 July 2017

Geier E

2

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29 July 2017

Lucchiari-Hartz M

3

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29 July 2017

Hitziger N

4

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29 July 2017

Ramsperger A

5

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29 July 2017

Eichmann K

6

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29 July 2017

publication date

1 December 1999

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29 July 2017

published in

Immunological Reviews

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29 July 2017

volume

172

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29 July 2017

page(s)

29-48

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

29 July 2017

1 reference

The proteasome: paradigm of a self-compartmentalizing protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Determinant selection of major histocompatibility complex class I-restricted antigenic peptides is explained by class I-peptide affinity and is strongly influenced by nondominant anchor residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

The proteolytic fragments generated by vertebrate proteasomes: structural relationships to major histocompatibility complex class I binding peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Modulation of proteasomal activity required for the generation of a cytotoxic T lymphocyte-defined peptide derived from the tumor antigen MAGE-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Contribution of proteasomal beta-subunits to the cleavage of peptide substrates analyzed with yeast mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

A role for the proteasome regulator PA28alpha in antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Flanking sequences influence the presentation of an endogenously synthesized peptide to cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

CD8+ T cell recognition of an endogenously processed epitope is regulated primarily by residues within the epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

The cleavage preference of the proteasome governs the yield of antigenic peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

The sequence alteration associated with a mutational hotspot in p53 protects cells from lysis by cytotoxic T lymphocytes specific for a flanking peptide epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Recognition of oligonucleotide-encoded T cell epitopes introduced into a gene unrelated to the original antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Presentation of viral antigen to class I major histocompatibility complex-restricted cytotoxic T lymphocyte. Recognition of an immunodominant influenza hemagglutinin site by cytotoxic T lymphocyte is independent of the position of the site in the he

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Inhibition of antigen processing by the internal repeat region of the Epstein-Barr virus nuclear antigen-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

A minimal glycine-alanine repeat prevents the interaction of ubiquitinated I kappaB alpha with the proteasome: a new mechanism for selective inhibition of proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

A glycine-rich region in NF-kappaB p105 functions as a processing signal for the generation of the p50 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

The active sites of the eukaryotic 20 S proteasome and their involvement in subunit precursor processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Effects of major-histocompatibility-complex-encoded subunits on the peptidase and proteolytic activities of human 20S proteasomes. Cleavage of proteins and antigenic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Altered properties of the branched chain amino acid-preferring activity contribute to increased cleavages after branched chain residues by the "immunoproteasome."

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Substrate binding and sequence preference of the proteasome revealed by active-site-directed affinity probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

A theoretical approach towards the identification of cleavage-determining amino acid motifs of the 20 S proteasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

MHC ligands and peptide motifs: first listing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Interferon gamma stimulation modulates the proteolytic activity and cleavage site preference of 20S mouse proteasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

The interferon-gamma-inducible 11 S regulator (PA28) and the LMP2/LMP7 subunits govern the peptide production by the 20 S proteasome in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Bovine spleen multicatalytic proteinase complex (proteasome). Replacement of X, Y, and Z subunits by LMP7, LMP2, and MECL1 and changes in properties and specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Potential immunocompetence of proteolytic fragments produced by proteasomes before evolution of the vertebrate immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Structure of 20S proteasome from yeast at 2.4 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Proteasome subunits encoded in the MHC are not generally required for the processing of peptides bound by MHC class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

LMP2+ proteasomes are required for the presentation of specific antigens to cytotoxic T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Altered peptidase and viral-specific T cell response in LMP2 mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Simultaneous binding of PA28 and PA700 activators to 20 S proteasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

The making of the dominant MHC class I ligand SYFPEITHI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Covalent modification of the active site threonine of proteasomal beta subunits and the Escherichia coli homolog HslV by a new class of inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

A giant protease with potential to substitute for some functions of the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Trimming of antigenic peptides in an early secretory compartment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Processing of major histocompatibility class I-restricted antigens in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Promiscuous liberation of MHC-class I-binding peptides from the C termini of membrane and soluble proteins in the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Sequence of a prominent 16-residue self-peptide bound to HLA-B27 in a lymphoblastoid cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Retention of empty MHC class I molecules by tapasin is essential to reconstitute antigen presentation in invertebrate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

To be or not to be a responder in T-cell responses: ubiquitous oligopeptides in all proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

A Single Residue Exchange Within a Viral CTL Epitope Alters Proteasome-Mediated Degradation Resulting in Lack of Antigen Presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

MHC-linked LMP gene products specifically alter peptidase activities of the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

On the active site of proteases. 3. Mapping the active site of papain; specific peptide inhibitors of papain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Contribution of proteasome-mediated proteolysis to the hierarchy of epitopes presented by major histocompatibility complex class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Degradation of oxidized insulin B chain by the multiproteinase complex macropain (proteasome)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Pituitary multicatalytic proteinase complex. Specificity of components and aspects of proteolytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Existence of a molecular ruler in proteasomes suggested by analysis of degradation products

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Decelerated degradation of short peptides by the 20S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Double-cleavage production of the CTL epitope by proteasomes and PA28: role of the flanking region

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Processive degradation of proteins and other catalytic properties of the proteasome from Thermoplasma acidophilum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Contribution of proline residue for efficient production of MHC class I ligands by proteasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

Self peptides bound by HLA class I molecules are derived from highly conserved regions of a set of evolutionarily conserved proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1999.TB01354.X

10.1111/J.1600-065X.1999.TB01354.X

21 January 2018

Identifiers

DOI

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29 July 2017

1 reference