Mice expressing the A53T mutant form of human alpha-synuclein exhibit hyperactivity and reduced anxiety-like behavior (Q33817178)

29 July 2017

title

Mice expressing the A53T mutant form of human alpha-synuclein exhibit hyperactivity and reduced anxiety-like behavior (English)

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29 July 2017

1 reference

Dianca R Graham

1

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29 July 2017

Anita Sidhu

series ordinal

2

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29 July 2017

language of work or name

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1 June 2010

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Journal of Neuroscience Research

29 July 2017

published in

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29 July 2017

volume

88

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29 July 2017

issue

8

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29 July 2017

page(s)

1777-1783

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Regulation of the norepinephrine transporter by alpha-synuclein-mediated interactions with microtubules

29 July 2017

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4 July 2018

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Attenuation of the norepinephrine transporter activity and trafficking via interactions with alpha-synuclein

4 July 2018

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Modulation of the trafficking of the human serotonin transporter by human alpha-synuclein

4 July 2018

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4 July 2018

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Disruption of the interaction of alpha-synuclein with microtubules enhances cell surface recruitment of the dopamine transporter

4 July 2018

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4 July 2018

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Mutations in the lipid-binding domain of α-synuclein confer overlapping, yet distinct, functional properties in the regulation of dopamine transporter activity

4 July 2018

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Modulation of dopamine transporter function by alpha-synuclein is altered by impairment of cell adhesion and by induction of oxidative stress

4 July 2018

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4 July 2018

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Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

4 July 2018

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4 July 2018

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4 July 2018

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Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis.

4 July 2018

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4 July 2018

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Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons

4 July 2018

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Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

4 July 2018

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Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

4 July 2018

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4 July 2018

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Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

4 July 2018

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4 July 2018

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Alpha-synuclein transgenic mice exhibit reduced anxiety-like behaviour.

4 July 2018

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Locomotor hyperactivity and alterations in dopamine neurotransmission are associated with overexpression of A53T mutant human alpha-synuclein in mice

30 October 2018

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Abundant neuritic inclusions and microvacuolar changes in a case of diffuse Lewy body disease with the A53T mutation in the alpha-synuclein gene.

30 October 2018

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Fibrillization of alpha-synuclein and tau in familial Parkinson's disease caused by the A53T alpha-synuclein mutation

30 October 2018

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Cross-linking of ubiquitin, HSP27, parkin, and alpha-synuclein by gamma-glutamyl-epsilon-lysine bonds in Alzheimer's neurofibrillary tangles

30 October 2018

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Evaluation of the hospital anxiety and depression scale in patients with Parkinson's disease.

30 October 2018

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Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.

30 October 2018

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Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death.

30 October 2018

1 reference

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Alpha-synuclein-positive structures in cases with sporadic Alzheimer's disease: morphology and its relationship to tau aggregation.

30 October 2018

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Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.

30 October 2018

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Parkinson's disease and anxiety: comorbidity with depression

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20077428

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Alpha-synuclein and Parkinson's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20077428

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/20077428

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/JNR.22331

1 reference

29 July 2017

1 reference

29 July 2017

1 reference