Synthesis and evaluation of monophosphoryl lipid A derivatives as fully synthetic self-adjuvanting glycoconjugate cancer vaccine carriers (Q33819711)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728423%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

title

Synthesis and evaluation of monophosphoryl lipid A derivatives as fully synthetic self-adjuvanting glycoconjugate cancer vaccine carriers (English)

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14 March 2020

1

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14 March 2020

author name string

Mohabul Mondal

series ordinal

2

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14 March 2020

Guochao Liao

series ordinal

3

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14 March 2020

Zhongwu Guo

series ordinal

4

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14 March 2020

publication date

14 April 2014

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Organic and Biomolecular Chemistry

14 March 2020

published in

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14 March 2020

volume

12

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14 March 2020

issue

20

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14 March 2020

page(s)

3238-3245

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Clustered carbohydrates in synthetic vaccines

14 March 2020

cites work

1 reference

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4 July 2018

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Immune recognition of tumor-associated mucin MUC1 is achieved by a fully synthetic aberrantly glycosylated MUC1 tripartite vaccine

4 July 2018

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Carbohydrate-monophosphoryl lipid a conjugates are fully synthetic self-adjuvanting cancer vaccines eliciting robust immune responses in the mouse

4 July 2018

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Recent development in carbohydrate-based cancer vaccines

4 July 2018

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Synthesis of a monophosphoryl lipid A derivative and its conjugation to a modified form of a tumor-associated carbohydrate antigen GM3.

4 July 2018

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Synthetic and immunological studies of 5'-N-phenylacetyl sTn to develop carbohydrate-based cancer vaccines and to explore the impacts of linkage between carbohydrate antigens and carrier proteins

4 July 2018

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Putting endotoxin to work for us: monophosphoryl lipid A as a safe and effective vaccine adjuvant

4 July 2018

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Improving the antigenicity of sTn antigen by modification of its sialic acid residue for development of glycoconjugate cancer vaccines

4 July 2018

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Synthesis and immunological properties of N-modified GM3 antigens as therapeutic cancer vaccines

4 July 2018

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Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock

4 July 2018

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Synthesis and biological evaluation of Rhizobium sin-1 lipid A derivatives

4 July 2018

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Synthesis of lipid A type carboxymethyl derivatives with ether chains instead of ester chains and their LPS-antagonistic activities

4 July 2018

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Taking toll: lipid A mimetics as adjuvants and immunomodulators

4 July 2018

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Structure and function of lipopolysaccharides.

4 July 2018

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Toll receptors, CD14, and macrophage activation and deactivation by LPS.

4 July 2018

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Recent developments in adjuvants for vaccines against infectious diseases

4 July 2018

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3-O-Desacyl monophosphoryl lipid A derivatives: synthesis and immunostimulant activities

4 July 2018

1 reference

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Identification of the mouse IgG3 receptor: implications for antibody effector function at the interface between innate and adaptive immunity

4 July 2018

1 reference

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Antigen localisation regulates immune responses in a dose- and time-dependent fashion: a geographical view of immune reactivity

4 July 2018

1 reference

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Bacterial endotoxin: molecular relationships of structure to activity and function

4 July 2018

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Separation and characterization of toxic and nontoxic forms of lipid A.

4 July 2018

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Synthetic and natural Escherichia coli free lipid A express identical endotoxic activities

4 July 2018

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Structure-activity relationship of lipid A: comparison of biological activities of natural and synthetic lipid A's with different fatty acid compositions

4 July 2018

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The role of cytophilic IgG3 antibody in T cell-mediated resistance to infection with the extracellular bacterium, Pseudomonas aeruginosa.

4 July 2018

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Biological activity of synthetic phosphonooxyethyl analogs of lipid A and lipid A partial structures

4 July 2018

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Structural characterization of the lipid A component of pathogenic Neisseria meningitidis

4 July 2018

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Lipid A and liposomes containing lipid A as antigens and adjuvants

4 July 2018

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Monophosphoryl lipid A analogues with varying 3-O-substitution: synthesis and potent adjuvant activity

21 January 2018

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Synthesis and biological evaluation of a lipid A derivative that contains an aminogluconate moiety

21 January 2018

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Enhancement of the immune response to poorly immunogenic gangliosides after incorporation into very small size proteoliposomes (VSSP).

21 January 2018

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Synthetic and Immunological Studies of sTn Derivatives Carrying 5-N-(p-Substituted Phenylacetyl)Sialic Acid for the Development of Effective Cancer Vaccines

21 January 2018

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Towards a Fully Synthetic Carbohydrate-Based Anticancer Vaccine: Synthesis and Immunological Evaluation of a Lipidated Glycopeptide Containing the Tumor-Associated Tn Antigen

21 January 2018

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Structure-activity relationship of synthetic toll-like receptor 4 agonists

21 January 2018

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12 December 2020

Fully synthetic vaccines consisting of tumor-associated MUC1 glycopeptides and a lipopeptide ligand of the Toll-like receptor 2

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12 December 2020

Fully synthetic self-adjuvanting thioether-conjugated glycopeptide-lipopeptide antitumor vaccines for the induction of complement-dependent cytotoxicity against tumor cells

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12 December 2020

Design of fully synthetic, self-adjuvanting vaccine incorporating the tumor-associated carbohydrate Tn antigen and lipoamino acid-based Toll-like receptor 2 ligand

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12 December 2020

Identifiers

DOI

10.1039/C4OB00390J

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728423%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

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14 March 2020

PubMed publication ID

24728423

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728423%20AND%20SRC:MED&resulttype=core&format=json