Site-directed mutagenesis of the virion host shutoff gene (UL41) of herpes simplex virus (HSV): analysis of functional differences between HSV type 1 (HSV-1) and HSV-2 alleles. (Q33822743)

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English	Site-directed mutagenesis of the virion host shutoff gene (UL41) of herpes simplex virus (HSV): analysis of functional differences between HSV type 1 (HSV-1) and HSV-2 alleles.	scientific article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10516018%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Site-directed mutagenesis of the virion host shutoff gene (UL41) of herpes simplex virus (HSV): analysis of functional differences between HSV type 1 (HSV-1) and HSV-2 alleles (English)

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1 November 2019

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inferred from title

Herpes simplex virus type 1

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Human herpesvirus 2

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author name string

D N Everly

1

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1 November 2019

G S Read

2

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1 November 2019

language of work or name

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1 November 1999

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1 November 2019

Journal of Virology

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1 November 2019

73

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1 November 2019

11

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1 November 2019

9117-9129

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1 November 2019

Interferons regulate the phenotype of wild-type and mutant herpes simplex viruses in vivo

1 reference

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Sequences of the ribonucleotide reductase-encoding genes of felid herpesvirus 1 and molecular phylogenetic analysis.

1 reference

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4 July 2018

Mutational analysis of the virion host shutoff gene (UL41) of herpes simplex virus (HSV): characterization of HSV type 1 (HSV-1)/HSV-2 chimeras

1 reference

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The virion host shutoff function of herpes simplex virus type 1 plays a role in corneal invasion and functions independently of the cell cycle

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Expression and function of the equine herpesvirus 1 virion-associated host shutoff homolog

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Analysis of conserved domains of UL41 of herpes simplex virus type 1 in virion host shutoff and pathogenesis

1 reference

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Stable binding of the herpes simplex virus ICP47 protein to the peptide binding site of TAP

1 reference

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Herpes simplex virus VP16 rescues viral mRNA from destruction by the virion host shutoff function

1 reference

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The virion host shutoff protein of herpes simplex virus type 1: messenger ribonucleolytic activity in vitro

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Identification and characterization of a small modular domain in the herpes simplex virus host shutoff protein sufficient for interaction with VP16.

1 reference

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4 July 2018

Human herpes simplex virus (HSV)-specific CD8+ CTL clones recognize HSV-2-infected fibroblasts after treatment with IFN-gamma or when virion host shutoff functions are disabled

1 reference

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4 July 2018

Effect of herpes simplex virus type-1 UL41 gene on the stability of mRNA from the cellular genes: beta-actin, fibronectin, glucose transporter-1, and docking protein, and on virus intraperitoneal pathogenicity to newborn mice

1 reference

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The pseudorabies virus host-shutoff homolog gene: nucleotide sequence and comparison with alphaherpesvirus protein counterparts

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Herpes simplex virus infection of human fibroblasts and keratinocytes inhibits recognition by cloned CD8+ cytotoxic T lymphocytes.

1 reference

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4 July 2018

Isolation of a herpes simplex virus type 1 mutant with a deletion in the virion host shutoff gene and identification of multiple forms of the vhs (UL41) polypeptide.

1 reference

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4 July 2018

A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes

1 reference

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4 July 2018

Herpes simplex virus VP16 forms a complex with the virion host shutoff protein vhs

1 reference

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4 July 2018

The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infection

1 reference

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4 July 2018

Herpes simplex virus inhibits host cell splicing, and regulatory protein ICP27 is required for this effect

1 reference

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4 July 2018

The Virion Host Shutoff Protein of Herpes Simplex Virus Inhibits Reporter Gene Expression in the Absence of Other Viral Gene Products

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Mutational analysis of the herpes simplex virus virion host shutoff protein: evidence that vhs functions in the absence of other viral proteins

1 reference

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Sequence analysis of the UL39, UL38, and UL37 homologues of bovine herpesvirus 1 and expression studies of UL40 and UL39, the subunits of ribonucleotide reductase

1 reference

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mRNA stability in mammalian cells

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Role of the virion host shutoff (vhs) of herpes simplex virus type 1 in latency and pathogenesis.

1 reference

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Herpes simplex virus mutants defective in the virion-associated shutoff of host polypeptide synthesis and exhibiting abnormal synthesis of alpha (immediate early) viral polypeptides

1 reference

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Early Virion-associated Suppression of Cellular Protein Synthesis by Herpes Simplex Virus is Accompanied by Inactivation of mRNA

1 reference

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Degradation of cellular mRNAs induced by a virion-associated factor during herpes simplex virus infection of Vero cells

1 reference

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Effects of herpes simplex virus on mRNA stability

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Herpes simplex virus-infected cells contain a function(s) that destabilizes both host and viral mRNAs

1 reference

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A mutant of herpes simplex virus type 1 exhibits increased stability of immediate-early (alpha) mRNAs

1 reference

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The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1.

1 reference

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Herpes simplex virus virion host shutoff function

1 reference

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Control of mRNA stability by the virion host shutoff function of herpes simplex virus

1 reference

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Inactivation of the shutoff gene (UL41) of herpes simplex virus types 1 and 2.

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Comparative DNA sequence analysis of the host shutoff genes of different strains of herpes simplex virus: type 2 strain HG52 encodes a truncated UL41 product

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Transfer of UL41, the gene controlling virion-associated host cell shutoff, between different strains of herpes simplex virus

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29 October 2018

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1 November 2019

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1 November 2019

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