Selective inhibitors of a PAF biosynthetic enzyme lysophosphatidylcholine acyltransferase 2 (Q33825093)

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18 March 2020

title

Selective inhibitors of a PAF biosynthetic enzyme lysophosphatidylcholine acyltransferase 2 (English)

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3

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author name string

Megumi Tarui

1

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18 March 2020

Hideo Shindou

2

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18 March 2020

Ryo Morimoto

4

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18 March 2020

Takeshi Harayama

5

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18 March 2020

Tomomi Hashidate

6

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18 March 2020

Hirotatsu Kojima

7

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18 March 2020

Takayoshi Okabe

8

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18 March 2020

Tetsuo Nagano

9

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Takahide Nagase

10

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18 March 2020

Takao Shimizu

11

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18 March 2020

publication date

21 May 2014

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Journal of Lipid Research

18 March 2020

published in

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volume

55

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issue

7

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page(s)

1386-1396

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AAV-mediated lysophosphatidylcholine acyltransferase 1 (Lpcat1) gene replacement therapy rescues retinal degeneration in rd11 mice.

18 March 2020

cites work

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4 July 2018

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Alkylglycerol monooxygenase as a potential modulator for PAF synthesis in macrophages

4 July 2018

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RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cells

4 July 2018

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Recent progress in phospholipase A₂ research: from cells to animals to humans

4 July 2018

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Inhibition of Bfl-1 with N-aryl maleimides

4 July 2018

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Loss of lysophosphatidylcholine acyltransferase 1 leads to photoreceptor degeneration in rd11 mice

4 July 2018

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Phosphorylation of Lysophosphatidylcholine Acyltransferase 2 at Ser34 Enhances Platelet-activating Factor Production in Endotoxin-stimulated Macrophages

4 July 2018

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Mouse and human eosinophils degranulate in response to platelet-activating factor (PAF) and lysoPAF via a PAF-receptor-independent mechanism: evidence for a novel receptor

4 July 2018

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LPCAT1 regulates surfactant phospholipid synthesis and is required for transitioning to air breathing in mice

4 July 2018

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Cancer prevention by tea: animal studies, molecular mechanisms and human relevance

4 July 2018

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The emerging roles of PAF acetylhydrolase

4 July 2018

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Lipid mediators in health and disease: enzymes and receptors as therapeutic targets for the regulation of immunity and inflammation

4 July 2018

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Acyl-CoA:lysophospholipid acyltransferases

4 July 2018

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A single enzyme catalyzes both platelet-activating factor production and membrane biogenesis of inflammatory cells. Cloning and characterization of acetyl-CoA:LYSO-PAF acetyltransferase

4 July 2018

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Identification and characterization of a lysophosphatidylcholine acyltransferase in alveolar type II cells

4 July 2018

1 reference

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Cloning and characterization of mouse lung-type acyl-CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1). Expression in alveolar type II cells and possible involvement in surfactant production

4 July 2018

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Identification of T cell death-associated gene 8 (TDAG8) as a novel acid sensing G-protein-coupled receptor

4 July 2018

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

4 July 2018

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Platelet-activating factor acetylhydrolase

4 July 2018

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Platelet-activating factor and related lipid mediators

4 July 2018

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Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice

4 July 2018

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Enzymatic synthesis of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine, a hypotensive and platelet-aggregating lipid.

4 July 2018

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Lack of platelet-activating factor receptor protects mice against diet-induced adipose inflammation and insulin-resistance despite fat pad expansion.

4 July 2018

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Antiobese function of platelet-activating factor: increased adiposity in platelet-activating factor receptor-deficient mice with age.

29 October 2018

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A Penicillium sp. F33 metabolite and its synthetic derivatives inhibit acetyl-CoA:1-O-alkyl-sn-glycero-3-phosphocholine acetyltransferase (a key enzyme in platelet-activating factor biosynthesis) and carrageenan-induced paw edema in mice.

29 October 2018

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Biosynthesis of phosphatidylcholine by human lysophosphatidylcholine acyltransferase 1.

29 October 2018

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A fluorescence-based thiol quantification assay for ultra-high-throughput screening for inhibitors of coenzyme A production

29 October 2018

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Identification of a novel noninflammatory biosynthetic pathway of platelet-activating factor

29 October 2018

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Tea polyphenols inhibit acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acetyltransferase (a key enzyme in platelet-activating factor biosynthesis) and platelet-activating factor-induced platelet aggregation

29 October 2018

1 reference

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Involvement of platelet-activating factor and LIS1 in neuronal migration.

29 October 2018

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Analysis of amino acid motifs diagnostic for the sn-glycerol-3-phosphate acyltransferase reaction

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24850807

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Platelet-activating factor production in the spinal cord of experimental allergic encephalomyelitis mice via the group IVA cytosolic phospholipase A2-lyso-PAFAT axis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24850807

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Priming effect of lipopolysaccharide on acetyl-coenzyme A:lyso-platelet-activating factor acetyltransferase is MyD88 and TRIF independent

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24850807

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1194/JLR.M049205

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24850807%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference

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18 March 2020

PubMed publication ID

24850807

1 reference