Challenges in preparing and implementing a clinical trial at field level in an Ebola emergency: A case study in Guinea, West Africa (Q33825147)

29 July 2017

Challenges in preparing and implementing a clinical trial at field level in an Ebola emergency: A case study in Guinea, West Africa (English)

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Western African Ebola virus epidemic

29 July 2017

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2014 Ebola virus epidemic in Guinea

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Orthoebolavirus zairense

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Sara Carazo Perez

1

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Piet Maes

object named as

Piet Maes

9

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Xavier Anglaret

3

object named as

Xavier Anglaret

1 reference

29 July 2017

6

Alseny-Modet Camara

1 reference

29 July 2017

11

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Evelyn Depoortere

7

object named as

Evelyn Depoortere

1 reference

29 July 2017

Elin Folkesson

2

1 reference

29 July 2017

Abdoul-Habib Beavogui

4

1 reference

29 July 2017

Emmanuel Berbain

5

1 reference

29 July 2017

Annabelle Lefevre

8

1 reference

29 July 2017

Kristian Nødtvedt Malme

10

1 reference

29 July 2017

Sien Ombelet

12

1 reference

29 July 2017

Geertrui Poelaert

13

1 reference

29 July 2017

Daouda Sissoko

14

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29 July 2017

Alexis Tounkara

15

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29 July 2017

Pierre Trbovic

16

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29 July 2017

Pascal Piguet

17

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29 July 2017

Annick Antierens

18

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29 July 2017

language of work or name

English

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publication date

22 June 2017

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PLoS Neglected Tropical Diseases

29 July 2017

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29 July 2017

11

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29 July 2017

e0005545

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29 July 2017

6

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Creative Commons Attribution 4.0 International

29 July 2017

start time

22 June 2017

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Experimental Treatment of Ebola Virus Disease with Brincidofovir

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

The Ebola clinical trials: a precedent for research ethics in disasters

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Social and cultural factors behind community resistance during an Ebola outbreak in a village of the Guinean Forest region, February 2015: a field experience.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Conducting clinical trials in outbreak settings: Points to consider

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Trial design for evaluating novel treatments during an outbreak of an infectious disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Evaluation of Convalescent Plasma for Ebola Virus Disease in Guinea

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Ebola viral disease and pregnancy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Ebola virus disease and Marburg disease in pregnancy: a review and management considerations for filovirus infection

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Are adaptive randomised trials or non-randomised studies the best way to address the Ebola outbreak in west Africa?

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Ebola virus disease 2013-2014 outbreak in west Africa: an analysis of the epidemic spread and response

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Ebola virus disease among children in West Africa

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Ebola outbreak in rural West Africa: epidemiology, clinical features and outcomes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Favipiravir: a new medication for the Ebola virus disease pandemic.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Evaluating Ebola therapies--the case for RCTs

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Randomised controlled trials for Ebola: practical and ethical issues

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Evaluating novel therapies during the Ebola epidemic

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Favipiravir (T-705) inhibits Junín virus infection and reduces mortality in a guinea pig model of Argentine hemorrhagic fever

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Favipiravir (T-705), a novel viral RNA polymerase inhibitor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Effective oral favipiravir (T-705) therapy initiated after the onset of clinical disease in a model of arenavirus hemorrhagic Fever

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Ebola haemorrhagic fever among hospitalised children and adolescents in northern Uganda: epidemiologic and clinical observations

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

Ebola virus disease in southern Sudan: hospital dissemination and intrafamilial spread

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480829

WHO gives go ahead for experimental treatments to be used in Ebola outbreak

4 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0005545

Favipiravir for children with Ebola

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0005545

10.1371/JOURNAL.PNTD.0005545

21 January 2018

Identifiers

DOI

1 reference

29 July 2017

1 reference

29 July 2017

1 reference