The effects of type II binding on metabolic stability and binding affinity in cytochrome P450 CYP3A4. (Q33827579)

29 July 2017

title

The effects of type II binding on metabolic stability and binding affinity in cytochrome P450 CYP3A4. (English)

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29 July 2017

Chi-Chi Peng

1

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29 July 2017

Josh T Pearson

2

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29 July 2017

Dan A Rock

3

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29 July 2017

Carolyn A Joswig-Jones

4

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29 July 2017

Jeffrey P Jones

5

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29 July 2017

language of work or name

English

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publication date

25 March 2010

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Archives of Biochemistry and Biophysics

29 July 2017

published in

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29 July 2017

volume

497

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29 July 2017

issue

1-2

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29 July 2017

page(s)

68-81

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Modulation of the cytochrome P450 reductase redox potential by the phospholipid bilayer

29 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2864005

Cytochrome P450 2C9 type II binding studies on quinoline-4-carboxamide analogues

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2864005

Modeling and synthesis of novel tight-binding inhibitors of cytochrome P450 2C9.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2864005

Theoretical perspective on the structure and mechanism of cytochrome P450 enzymes.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2864005

P450 interaction with HIV protease inhibitors: relationship between metabolic stability, inhibitory potency, and P450 binding spectra

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2864005

Inhibitors of Cytochrome P-450s and their mechanism of action

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2864005

Steady-state enzyme kinetics with high-affinity substrates or inhibitors. A statistical treatment of dose-response curves

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2864005

Correlation of type I, type II, and reverse type I difference spectra with absolute changes in spin state of hepatic microsomal cytochrome P-450 iron from five mammalian species

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2864005

High confidence predictions of drug-drug interactions: predicting affinities for cytochrome P450 2C9 with multiple computational methods.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2864005

Visible spectra of type II cytochrome P450-drug complexes: evidence that "incomplete" heme coordination is common.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2864005

Surface plasmon resonance analysis of antifungal azoles binding to CYP3A4 with kinetic resolution of multiple binding orientations

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2864005

Differential roles of Arg97, Asp293, and Arg108 in enzyme stability and substrate specificity of CYP2C9.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2864005

P450 interaction with farnesyl-protein transferase inhibitors metabolic stability, inhibitory potency, and P450 binding spectra in human liver microsomes

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2864005

Electronic Ground States of Iron Porphyrin and of the First Species in the Catalytic Reaction Cycle of Cytochrome P450s

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2864005

Can a single oxidant with two spin states masquerade as two different oxidants? A study of the sulfoxidation mechanism by cytochrome p450

29 October 2018

1 reference

12 December 2020

Evaluation of cytochrome P450 mechanism and kinetics using kinetic deuterium isotope effects

1 reference

12 December 2020

Positive effectors of the binding of an active site-directed amino steroid to rabbit cytochrome P-450 3c

1 reference

12 December 2020

Formation of the active species of cytochrome p450 by using iodosylbenzene: a case for spin-selective reactivity

1 reference

12 December 2020

Energy-consistent relativistic pseudopotentials and correlation consistent basis sets for the 4d elements Y-Pd

1 reference

12 December 2020

Intramolecular isotope effects for benzylic hydroxylation of isomeric xylenes and 4,4'-dimethylbiphenyl by cytochrome P450: relationship between distance of methyl groups and masking of the intrinsic isotope effect

1 reference

12 December 2020

10.1016/J.ABB.2010.03.011

Identifiers

DOI

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29 July 2017

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29 July 2017

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