Identification of receptor-binding residues in the inflammatory complement protein C5a by site-directed mutagenesis (Q33829523)

29 July 2017

Identification of receptor-binding residues in the inflammatory complement protein C5a by site-directed mutagenesis (English)

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29 July 2017

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Mollison KW

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Mandecki W

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Zuiderweg ER

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Fayer L

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Fey TA

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Krause RA

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Conway RG

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Miller L

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Edalji RP

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Shallcross MA

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language of work or name

English

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publication date

1 January 1989

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29 July 2017

5

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Proceedings of the National Academy of Sciences of the United States of America

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published in

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86

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1

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292-296

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describes a project that uses

29 July 2017

site-directed mutagenesis

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The effects of some antirheumatic drugs on an in vitro model of human polymorphonuclear leucocyte chemokinesis

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cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

Demonstration of a specific receptor for human C5a anaphylatoxin on murine macrophages

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

The structural basis for anaphylatoxin and chemotactic functions of C3a, C4a, and C5a.

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

The active site of C3a anaphylatoxin.

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

Structure and function of the anaphylatoxins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

Regulation of immune response by components of the complement cascade and their activated fragments

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

Chemical synthesis of a gene encoding the human complement fragment C5a and its expression in Escherichia coli

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

Chemotactic responses of human peripheral blood monocytes to the complement-derived peptides C5a and C5a des Arg.

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

Oligonucleotide-directed double-strand break repair in plasmids of Escherichia coli: a method for site-specific mutagenesis

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

Role of the N-terminal regions of hog C3a, C5a and C5a-desArg in their biological activities.

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

Sequence-specific assignments in the proton NMR spectrum of the human inflammatory protein C5a

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

Secondary structure of complement component C3a anaphylatoxin in solution as determined by NMR spectroscopy: differences between crystal and solution conformations

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

C5a fragment of bovine complement. Purification, bioassays, amino-acid sequence and other structural studies

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

Primary structure of the fifth component of murine complement

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

Co-expression of chemotactic ligand receptors on human peripheral blood monocytes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

Primary structural analysis of the polypeptide portion of human C5a anaphylatoxin. Polypeptide sequence determination and assignment of the oligosaccharide attachment site in C5a

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

The Complement System in Host Defense and Inflammation

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

Chemotactic response to human C3a and C5a anaphylatoxins. I. Evaluation of C3a and C5a leukotaxis in vitro and under stimulated in vivo conditions

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

Demonstration of specific C5a receptor on intact human polymorphonuclear leukocytes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

Conformational analysis of COOH-terminal segments of human C3a. Evidence of ordered conformation in an active 21-residue peptide

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

Evidence for a role of the amino-terminal region in the biological activity of the classical anaphylatoxin, porcine C5a des-Arg-74.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286450

Molecular aspects of the serum chemotactic factors

29 October 2018

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12 December 2020

Amino acid sequence of the anaphylatoxin from the fifth component of porcine complement

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12 December 2020

Crystal structure analysis and molecular model of human C3a anaphylatoxin

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12 December 2020

Active site of C3a anaphylatoxin: contributions of the lipophilic and orienting residues

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12 December 2020

Amino-acid sequence and disulfide linkages of the anaphylatoxin, des-Arg omega-C5a, from porcine serum

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12 December 2020

Model structure for the inflammatory protein C5a

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12 December 2020

Structure and function of human C5a anaphylatoxin. Selective modification of tyrosine 23 alters biological activity but not antigenicity

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12 December 2020

High-level expression of a gene encoding the human complement factor C5a in Escherichia coli

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12 December 2020

Comparative structural anatomy of the complement anaphylatoxin proteins C3a, C4a and C5a

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12 December 2020

Identification of an antigenic epitope and receptor binding domain of human C5a

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12 December 2020

High-level C5a gene expression and recovery of recombinant human C5a from Escherichia coli

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12 December 2020

Comparison of model and nuclear magnetic resonance structures for the human inflammatory protein C5a

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12 December 2020

Identifiers

DOI

10.1073/PNAS.86.1.292

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29 July 2017

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29 July 2017

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