The R-enantiomer of the nonsteroidal antiinflammatory drug etodolac binds retinoid X receptor and induces tumor-selective apoptosis (Q33830812)

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8 January 2020

title

The R-enantiomer of the nonsteroidal antiinflammatory drug etodolac binds retinoid X receptor and induces tumor-selective apoptosis (English)

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8 January 2020

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4

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8 January 2020

author name string

Siva Kumar Kolluri

1

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8 January 2020

Maripat Corr

2

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8 January 2020

Sharon Y James

3

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8 January 2020

Desheng Lu

5

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8 January 2020

Wen Liu

6

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8 January 2020

Howard B Cottam

7

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8 January 2020

Lorenzo M Leoni

8

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8 January 2020

Dennis A Carson

9

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8 January 2020

Xiao-kun Zhang

10

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8 January 2020

language of work or name

English

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publication date

7 February 2005

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Proceedings of the National Academy of Sciences of the United States of America

8 January 2020

published in

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8 January 2020

volume

102

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8 January 2020

page(s)

2525-2530

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8 January 2020

issue

7

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Retinoid X receptor regulates Nur77/TR3-dependent apoptosis [corrected] by modulating its nuclear export and mitochondrial targeting

8 January 2020

cites work

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Suppression of prostate carcinogenesis by dietary supplementation of celecoxib in transgenic adenocarcinoma of the mouse prostate model

28 July 2018

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Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3

28 July 2018

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Activation of the Wnt signaling pathway in chronic lymphocytic leukemia

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Urban renewal in the nucleus: is protein turnover by proteasomes absolutely required for nuclear receptor-regulated transcription?

28 July 2018

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Mitogenic Effect of Orphan Receptor TR3 and Its Regulation by MEKK1 in Lung Cancer Cells

28 July 2018

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Regulation of retinoic acid receptor beta expression by peroxisome proliferator-activated receptor gamma ligands in cancer cells.

28 July 2018

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Prostatic intraepithelial neoplasia in mice with conditional disruption of the retinoid X receptor alpha allele in the prostate epithelium

28 July 2018

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Discovery and design of retinoic acid receptor and retinoid X receptor class- and subtype-selective synthetic analogs of all-trans-retinoic acid and 9-cis-retinoic acid

28 July 2018

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A population-based study of daily nonsteroidal anti-inflammatory drug use and prostate cancer

28 July 2018

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Is inhibition of cyclooxygenase required for the anti-tumorigenic effects of nonsteroidal, anti-inflammatory drugs (NSAIDs)? In vitro versus in vivo results and the relevance for the prevention and treatment of cancer

28 July 2018

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The rexinoid LG100754 is a novel RXR:PPARgamma agonist and decreases glucose levels in vivo

28 July 2018

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Chemotherapy in advanced androgen-independent prostate cancer 1990-1999: a decade of progress?

28 July 2018

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Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3.

28 July 2018

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E-7869 (R-flurbiprofen) inhibits progression of prostate cancer in the TRAMP mouse

28 July 2018

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Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells

28 July 2018

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Modulation of retinoic acid sensitivity in lung cancer cells through dynamic balance of orphan receptors nur77 and COUP-TF and their heterodimerization

28 July 2018

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Aberrant metabolism of retinoid X receptor proteins in human hepatocellular carcinoma

28 July 2018

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RXRalpha-null F9 embryonal carcinoma cells are resistant to the differentiation, anti-proliferative and apoptotic effects of retinoids

28 July 2018

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Activation of specific RXR heterodimers by an antagonist of RXR homodimers

28 July 2018

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Metastatic prostate cancer in a transgenic mouse

28 July 2018

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Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life?

28 July 2018

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The RXR heterodimers and orphan receptors

28 July 2018

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Etodolac clinical pharmacokinetics

28 July 2018

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Prostate cancer in a transgenic mouse

28 July 2018

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Application of a stereospecific high-performance liquid chromatography assay to a pharmacokinetic study of etodolac enantiomers in humans

28 July 2018

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Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid

28 July 2018

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Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors

28 July 2018

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COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib

28 July 2018

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Crossref

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Inhibition of HER-kinase activation prevents ERK-mediated degradation of PPARgamma

21 January 2018

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Direct functional interactions between insulin-like growth factor-binding protein-3 and retinoid X receptor-alpha regulate transcriptional signaling and apoptosis

21 January 2018

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Phosphorylation of retinoid X receptor alpha at serine 260 impairs its metabolism and function in human hepatocellular carcinoma

21 January 2018

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Cyclooxygenase-2 inhibitors suppress the growth of gastric cancer xenografts via induction of apoptosis in nude mice

29 October 2018

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12 December 2020

Resolution of etodolac and antiinflammatory and prostaglandin synthetase inhibiting properties of the enantiomers

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12 December 2020

Gastrointestinal damage associated with the use of nonsteroidal antiinflammatory drugs

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12 December 2020

Ligand-induced alteration of the protease sensitivity of retinoid X receptor alpha

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12 December 2020

Nonsteroidal antiinflammatory drugs inhibit the proliferation of colon adenocarcinoma cells: effects on cell cycle and apoptosis

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12 December 2020

Inverse association of prostate cancer and non-steroidal anti-inflammatory drugs (NSAIDs): results of a case-control study

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12 December 2020

Non-steroidal anti-inflammatory drugs and prostate cancer progression

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0409721102

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8 January 2020

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8 January 2020

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