Platelet-derived growth factor-DD targeting arrests pathological angiogenesis by modulating glycogen synthase kinase-3beta phosphorylation (Q33832464)

29 July 2017

Platelet-derived growth factor-DD targeting arrests pathological angiogenesis by modulating glycogen synthase kinase-3beta phosphorylation (English)

1 reference

29 July 2017

1 reference

Triantafyllos Chavakis

16

object named as

Triantafyllos Chavakis

1 reference

29 July 2017

Anil Kumar

1

1 reference

29 July 2017

Xu Hou

2

1 reference

29 July 2017

Chunsik Lee

3

1 reference

29 July 2017

Yang Li

4

1 reference

29 July 2017

Arvydas Maminishkis

5

1 reference

29 July 2017

Zhongshu Tang

6

1 reference

29 July 2017

Fan Zhang

7

1 reference

29 July 2017

Harald F Langer

8

1 reference

29 July 2017

Pachiappan Arjunan

9

1 reference

29 July 2017

Lijin Dong

10

1 reference

29 July 2017

Zhijian Wu

11

1 reference

29 July 2017

Linda Y Zhu

12

1 reference

29 July 2017

Lianchun Wang

13

1 reference

29 July 2017

Wang Min

14

1 reference

29 July 2017

Peter Colosi

15

1 reference

29 July 2017

Xuri Li

17

1 reference

29 July 2017

language of work or name

English

0 references

publication date

15 March 2010

1 reference

Journal of Biological Chemistry

29 July 2017

1 reference

29 July 2017

285

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29 July 2017

20

1 reference

29 July 2017

15500-15510

1 reference

Modulating the hypoxia-inducible factor signaling pathway as a therapeutic modality to regulate retinal angiogenesis

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Branching morphogenesis and antiangiogenesis candidates: tip cells lead the way.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Histone H2AX is integral to hypoxia-driven neovascularization

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Involvement of hyaluronan and its receptor CD44 with choroidal neovascularization

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Drug development targeting the glycogen synthase kinase-3beta (GSK-3beta)-mediated signal transduction pathway: inhibitors of the Wnt/beta-catenin signaling pathway as novel anticancer drugs

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Therapeutic monoclonal antibodies in ophthalmology

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Lithium reduces Gsk3b mRNA levels: implications for Alzheimer Disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Ranibizumab for neovascular age-related macular degeneration.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

A reproducible and quantifiable model of choroidal neovascularization induced by VEGF A165 after subretinal adenoviral gene transfer in the rabbit.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Inhibitors of vascular endothelial growth factor (VEGF) in the management of neovascular age-related macular degeneration: a review of current practice.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Effects of PDGF-C and PDGF-D on monocyte migration and MMP-2 and MMP-9 expression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

MCP-1 deficiency delays regression of pathologic retinal neovascularization in a model of ischemic retinopathy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Vascular adhesion protein-1 blockade suppresses choroidal neovascularization.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Platelet-derived growth factor-D overexpression contributes to epithelial-mesenchymal transition of PC3 prostate cancer cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

VEGF and TGF-beta are required for the maintenance of the choroid plexus and ependyma

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

VEGF-B inhibits apoptosis via VEGFR-1-mediated suppression of the expression of BH3-only protein genes in mice and rats

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Identification of platelet-derived growth factor D in human chronic allograft nephropathy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Anti-vascular endothelial growth factor therapy for ocular neovascular disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Pericytes and ocular diseases

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Vascular endothelial growth factor-A is a survival factor for retinal neurons and a critical neuroprotectant during the adaptive response to ischemic injury.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Angiogenesis: an organizing principle for drug discovery?

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Proangiogenic role of ephrinB1/EphB1 in basic fibroblast growth factor-induced corneal angiogenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Combination angiostatic therapy completely inhibits ocular and tumor angiogenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

A novel imaging technique for experimental choroidal neovascularization

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Myeloid progenitors differentiate into microglia and promote vascular repair in a model of ischemic retinopathy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Overexpression of FasL in retinal pigment epithelial cells reduces choroidal neovascularization

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Recombinant non-collagenous domain of alpha2(IV) collagen causes involution of choroidal neovascularization by inducing apoptosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Angiogenesis as a therapeutic target

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Angiogenesis in life, disease and medicine

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Inhibition of pathologic retinal neovascularization by alpha-defensins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Blocking platelet-derived growth factor-D/platelet-derived growth factor receptor beta signaling inhibits human renal cell carcinoma progression in an orthotopic mouse model

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

The oncogene PDGF-B provides a key switch from cell death to survival induced by TNF.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Platelet-derived growth factor D, tissue-specific expression in the eye, and a key role in control of lens epithelial cell proliferation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

High interstitial fluid pressure - an obstacle in cancer therapy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Regulatory mechanisms for the expression and activity of platelet-derived growth factor receptor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Decorin inhibition of PDGF-stimulated vascular smooth muscle cell function: potential mechanism for inhibition of intimal hyperplasia after balloon angioplasty

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Placental growth factor, a member of the VEGF family, contributes to the development of choroidal neovascularization

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

PDGF-D is a potent transforming and angiogenic growth factor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Dictyostelium differentiation-inducing factor-3 activates glycogen synthase kinase-3beta and degrades cyclin D1 in mammalian cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Role of phosphoinositide 3OH-kinase in autocrine transformation by PDGF-BB.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Chromosomal location, exon structure, and vascular expression patterns of the human PDGFC and PDGFD genes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

PDGF-D, a new protease-activated growth factor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

TNF-alpha suppresses the PDGF beta-receptor kinase

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Overexpression of vascular endothelial growth factor (VEGF) in the retinal pigment epithelium leads to the development of choroidal neovascularization

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Isolation and in vitro propagation of human choroidal fibroblasts. Morphology and characterization of the cultures

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

Autocrine stimulation of intracellular PDGF receptors in v-sis-transformed cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865282

PDGF-C and -D and their receptors PDGFR-alpha and PDGFR-beta in atherosclerotic human arteries.

4 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113787

PDGF-A, -C, and -D but not PDGF-B increase TGF-beta1 and chronic rejection in rat cardiac allografts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113787

PDGF-C and -D induced proliferation/migration of human RPE is abolished by inflammatory cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113787

Combinatory inhibition of VEGF and FGF2 is superior to solitary VEGF inhibition in an in vitro model of RPE-induced angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113787

Effects of decorin and biglycan on human airway smooth muscle cell proliferation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113787

Retroviral overexpression of decorin differentially affects the response of arterial smooth muscle cells to growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113787

Mediation of electronegative low-density lipoprotein signaling by LOX-1: a possible mechanism of endothelial apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113787

Increase of PTP levels in vascular injury and in cultured aortic smooth muscle cells treated with specific growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113787

Counter-regulatory function of protein tyrosine phosphatase 1B in platelet-derived growth factor- or fibroblast growth factor-induced motility and proliferation of cultured smooth muscle cells and in neointima formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113787

Akt regulates the survival of vascular smooth muscle cells via inhibition of FoxO3a and GSK3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113787

Regulation and function of glycogen synthase kinase-3 isoforms in neuronal survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113787

Improved quantification of angiogenesis in the rat aortic ring assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113787

Involvement of glycogen synthase kinase-3beta in palmitate-induced human umbilical vein endothelial cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113787

Enhanced glycogen synthase kinase-3beta activity mediates hypoxia-induced apoptosis of vascular smooth muscle cells and is prevented by glucose transport and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113787

Comparative evaluation of apoptotic activity in photoreceptor cells after intravitreal injection of bevacizumab and pegaptanib sodium in rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113787

Preclinical safety evaluation of intravitreal injection of full-length humanized vascular endothelial growth factor antibody in rabbit eyes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113787

Testing intravitreal toxicity of bevacizumab (Avastin).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113787

Apoptosis in surgically excised choroidal neovascular membranes in age-related macular degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113787

Down-regulation of Platelet-Derived Growth Factor-D Inhibits Cell Growth and Angiogenesis through Inactivation of Notch-1 and Nuclear Factor-κB Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.113787

Vascular endothelial growth factor

21 January 2018

1 reference

12 December 2020

The thin prep rat aortic ring assay: a modified method for the characterization of angiogenesis in whole mounts

1 reference

12 December 2020

Coexpression of a PDGF-like growth factor and PDGF receptors in a human osteosarcoma cell line: Implications for autocrine receptor activation

1 reference

12 December 2020

Expression and regulation of vascular endothelial growth factor in choroidal fibroblasts

1 reference

12 December 2020

Progression of choroidal neovascularization following injection of pegaptanib sodium (macugen) in two eyes with neovascular age-related macular degeneration

1 reference

12 December 2020

Ultrastructural findings in the primate eye after intravitreal injection of bevacizumab

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.113787

1 reference

29 July 2017

1 reference

29 July 2017

1 reference