Synphilin-1 attenuates neuronal degeneration in the A53T alpha-synuclein transgenic mouse model (Q33832846)

29 July 2017

title

Synphilin-1 attenuates neuronal degeneration in the A53T alpha-synuclein transgenic mouse model (English)

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29 July 2017

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13

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7

Neal G Copeland

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6

Nancy A Jenkins

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10

Ted M Dawson

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15

Christopher A Ross

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Wanli W Smith

1

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29 July 2017

Zhaohui Liu

2

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29 July 2017

Yideng Liang

3

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29 July 2017

Naoki Masuda

4

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Debbie A Swing

5

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Juan C Troncoso

8

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29 July 2017

Mikhail Pletnikov

9

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Lee J Martin

11

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Timothy H Moran

12

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David R Borchelt

14

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29 July 2017

publication date

25 February 2010

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29 July 2017

published in

Human Molecular Genetics

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29 July 2017

volume

19

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issue

11

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29 July 2017

page(s)

2087-2098

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describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2865369/fullTextXML

inferred from PubMed Central ID database lookup

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Transgenic overexpression of the alpha-synuclein interacting protein synphilin-1 leads to behavioral and neuropathological alterations in mice

28 July 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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Caspase-3-derived C-terminal product of synphilin-1 displays antiapoptotic function via modulation of the p53-dependent cell death pathway.

29 October 2018

1 reference

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Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.

29 October 2018

1 reference

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Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865369

Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865369

Alpha-synuclein phosphorylation enhances eosinophilic cytoplasmic inclusion formation in SH-SY5Y cells.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865369

Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865369

Microtubule disruption inhibits autophagosome-lysosome fusion: implications for studying the roles of aggresomes in polyglutamine diseases

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865369

Proteasomal inhibition by alpha-synuclein filaments and oligomers.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865369

α-Synuclein Is Degraded by Both Autophagy and the Proteasome

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865369

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865369

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865369

Synphilin-1 is developmentally localized to synaptic terminals, and its association with synaptic vesicles is modulated by alpha-synuclein

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865369

Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865369

Synphilin-1 is present in Lewy bodies in Parkinson's disease

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20185556

12 December 2020

inferred from PubMed ID database lookup

Neuropathology in mice expressing human alpha-synuclein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20185556

12 December 2020

inferred from PubMed ID database lookup

A vector for expressing foreign genes in the brains and hearts of transgenic mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20185556

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1093/HMG/DDQ086

1 reference

release_bdogiszzhfbdhjchkur4vh772q

29 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bdogiszzhfbdhjchkur4vh772q

24 November 2022

mapped directly with Wikidata item

PMC publication ID

2865369

1 reference

29 July 2017

1 reference