Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease (Q33832866)

29 July 2017

Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease (English)

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29 July 2017

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Silvia Corrochano

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Abraham Acevedo-Arozena

object named as

Abraham Acevedo-Arozena

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author name string

Claudia Rose

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29 July 2017

Fiona M Menzies

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29 July 2017

Maurizio Renna

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29 July 2017

Oana Sadiq

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29 July 2017

Steve D Brown

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29 July 2017

David C Rubinsztein

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29 July 2017

27 February 2010

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29 July 2017

Human Molecular Genetics

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29 July 2017

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29 July 2017

2144-2153

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29 July 2017

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describes a project that uses

29 July 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2865373/fullTextXML

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

28 July 2018

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28 July 2018

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28 July 2018

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Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

28 July 2018

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Reduced basal ganglia volume associated with the gene for Huntington's disease in asymptomatic at-risk persons.

28 July 2018

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Neuropathological classification of Huntington's disease

28 July 2018

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Cardiovascular and central nervous system effects of rilmenidine (S 3341) in rats

28 July 2018

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Rilmenidine: a novel antihypertensive agent

28 July 2018

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28 July 2018

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Binding of [3H]p-aminoclonidine to two sites, alpha 2-adrenoceptors and imidazoline binding sites: distribution of imidazoline binding sites in rat brain.

28 July 2018

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Distinctive features of rilmenidine possibly related to its selectivity for imidazoline receptors

28 July 2018

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Onset and rate of striatal atrophy in preclinical Huntington disease

28 July 2018

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Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

21 January 2018

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Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin

21 January 2018

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

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Formation of polyglutamine inclusions in non-CNS tissue

21 January 2018

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Weight loss in Huntington disease increases with higher CAG repeat number

21 January 2018

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Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration

21 January 2018

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Regulation of cell growth by autophagy

21 January 2018

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In search of an "autophagomometer".

21 January 2018

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Detection of polyglutamine aggregation in mouse models

29 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865373

Imidazoline receptors, non-adrenergic idazoxan binding sites and alpha 2-adrenoceptors in the human central nervous system.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865373

Quantitative autoradiographic localization in rat brain of alpha 2-adrenergic and non-adrenergic I-receptor binding sites labelled by [3H]rilmenidine

29 October 2018

1 reference

12 December 2020

Relative importance of central imidazoline receptors for the antihypertensive effects of moxonidine and rilmenidine

1 reference

12 December 2020

Clonidine binds to imidazole binding sites as well as alpha 2-adrenoceptors in the ventrolateral medulla

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12 December 2020

Imidazoline-induced neuroprotective effects result from blockade of NMDA receptor channels in neuronal cultures

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12 December 2020

Identifiers

DOI

10.1093/HMG/DDQ093

1 reference

29 July 2017

1 reference

29 July 2017

1 reference