Genome-Wide DNA Methylation Study Identifies Significant Epigenomic Changes in Osteoarthritic Subchondral Bone and Similarity to Overlying Cartilage (Q33833496)

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English	Genome-Wide DNA Methylation Study Identifies Significant Epigenomic Changes in Osteoarthritic Subchondral Bone and Similarity to Overlying Cartilage	scientific article

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scholarly article

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Europe PubMed Central

29 July 2017

Genome-Wide DNA Methylation Study Identifies Significant Epigenomic Changes in Osteoarthritic Subchondral Bone and Similarity to Overlying Cartilage (English)

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Europe PubMed Central

29 July 2017

DNA methylation

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Matlock Jeffries

object named as

Matlock A Jeffries

1

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Judith A. James

7

object named as

Judith A James

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Europe PubMed Central

29 July 2017

author name string

Madison Donica

2

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Europe PubMed Central

29 July 2017

Lyle W Baker

3

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Europe PubMed Central

29 July 2017

Michael E Stevenson

4

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Europe PubMed Central

29 July 2017

Anand C Annan

5

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Europe PubMed Central

29 July 2017

Mary Beth Humphrey

6

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Europe PubMed Central

29 July 2017

Amr H Sawalha

8

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29 July 2017

language of work or name

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publication date

29 December 2015

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Europe PubMed Central

29 July 2017

Arthritis & Rheumatology

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Europe PubMed Central

29 July 2017

68

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Europe PubMed Central

29 July 2017

1403-1414

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Europe PubMed Central

29 July 2017

6

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Europe PubMed Central

29 July 2017

RNAi Silencing of IL-1β and TNF-α in the Treatment of Post-traumatic Arthritis in Rabbits.

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Histone deacetylase 4 alters cartilage homeostasis in human osteoarthritis

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Decreased histone deacetylase 4 is associated with human osteoarthritis cartilage degeneration by releasing histone deacetylase 4 inhibition of runt-related transcription factor-2 and increasing osteoarthritis-related genes: a novel mechanism of hum

1 reference

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Meta-analysis of tumor necrosis factor alpha -308 polymorphism and knee osteoarthritis risk

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Epigenetic differences in human cartilage between mild and severe OA.

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4 July 2018

Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage

1 reference

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Bone-cartilage interface crosstalk in osteoarthritis: potential pathways and future therapeutic strategies

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Characterization of the cartilage DNA methylome in knee and hip osteoarthritis

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Bioenergetics and gene silencing approaches for unraveling nucleotide recognition by the human EIF2C2/Ago2 PAZ domain.

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A coregulatory network of NR2F1 and microRNA-140

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NFATc1 and NFATc2 repress spontaneous osteoarthritis

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Molecular study of a Hoxa2 gain-of-function in chondrogenesis: a model of idiopathic proportionate short stature

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The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a Mendelian randomisation study

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4 July 2018

Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis

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Genome-wide DNA methylation analysis of articular chondrocytes reveals a cluster of osteoarthritic patients

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The dramatic increase in total knee replacement utilization rates in the United States cannot be fully explained by growth in population size and the obesity epidemic

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Genome wide analysis reveals association of a FTO gene variant with epigenetic changes

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Tumour necrosis factor blockade for the treatment of erosive osteoarthritis of the interphalangeal finger joints: a double blind, randomised trial on structure modification

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MicroRNA in osteoarthritis

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Regeneration of the articular surface of the rabbit synovial joint by cell homing: a proof of concept study

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Genome-wide linkage analysis of quantitative biomarker traits of osteoarthritis in a large, multigenerational extended family

1 reference

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Oxidative stress inhibits insulin-like growth factor-I induction of chondrocyte proteoglycan synthesis through differential regulation of phosphatidylinositol 3-Kinase-Akt and MEK-ERK MAPK signaling pathways

1 reference

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Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation

1 reference

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4 July 2018

Change in MRI-detected subchondral bone marrow lesions is associated with cartilage loss: the MOST Study. A longitudinal multicentre study of knee osteoarthritis

1 reference

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Mitogen-activated protein kinases as therapeutic targets in osteoarthritis

1 reference

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The induction of endochondral bone formation by transforming growth factor-beta(3): experimental studies in the non-human primate Papio ursinus

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NFAT and Osterix cooperatively regulate bone formation

1 reference

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Down-regulation of Hox A7 is required for cell adhesion and migration on fibronectin during early HL-60 monocytic differentiation

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IGF/IGFBP axis in cartilage and bone in osteoarthritis pathogenesis

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A navigator for human genome epidemiology.

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Transforming growth factor-beta3 promotes mesenchymal cell proliferation and angiogenesis mediated by the enhancement of cyclin D1, Flk-1, and CD31 gene expression during CL/Fr mouse lip fusion.

1 reference

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21 January 2018

Combination of MEK-ERK inhibitor and hyaluronic acid has a synergistic effect on anti-hypertrophic and pro-chondrogenic activities in osteoarthritis treatment.

1 reference

https://api.crossref.org/works/10.1002%2FART.39555

21 January 2018

Women with osteoarthritis have elevated synovial fluid levels of insulin-like growth factor (IGF)-1 and IGF-binding protein-3.

1 reference

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21 January 2018

Reproducible genetic associations between candidate genes and clinical knee osteoarthritis in men and women.

1 reference

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21 January 2018

Genome-wide profiling of bone reveals differentially methylated regions in osteoporosis and osteoarthritis

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https://api.crossref.org/works/10.1002%2FART.39555

21 January 2018

A pilot study of tumor necrosis factor inhibition in erosive/inflammatory osteoarthritis of the hands

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29 October 2018

Elevated serum levels of soluble interleukin-4 receptor in osteoarthritis

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29 October 2018

Adalimumab in patients with hand osteoarthritis refractory to analgesics and NSAIDs: a randomised, multicentre, double-blind, placebo-controlled trial

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https://pubmed.ncbi.nlm.nih.gov/26713865

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inferred from PubMed ID database lookup

Expression of Hoxa2 in cells entering chondrogenesis impairs overall cartilage development

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https://pubmed.ncbi.nlm.nih.gov/26713865

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based on heuristic

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Resemblance of osteophytes in experimental osteoarthritis to transforming growth factor beta-induced osteophytes: limited role of bone morphogenetic protein in early osteoarthritic osteophyte formation

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https://pubmed.ncbi.nlm.nih.gov/26713865

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Signature of circulating microRNAs in osteoarthritis

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https://pubmed.ncbi.nlm.nih.gov/26713865

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/ART.39555

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Europe PubMed Central

29 July 2017

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Europe PubMed Central

29 July 2017

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Europe PubMed Central

29 July 2017

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