Aggregation of a multidomain protein: a coagulation mechanism governs aggregation of a model IgG1 antibody under weak thermal stress (Q33834215)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20014440%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Aggregation of a multidomain protein: a coagulation mechanism governs aggregation of a model IgG1 antibody under weak thermal stress (English)

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Christian Beyschau Andersen

15 January 2020

author

1

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15 January 2020

Mauro Manno

2

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15 January 2020

Vincenzo Martorana

5

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15 January 2020

author name string

Christian Rischel

3

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15 January 2020

Matthías Thórólfsson

4

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15 January 2020

publication date

1 February 2010

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15 January 2020

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15 January 2020

volume

19

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15 January 2020

issue

2

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15 January 2020

page(s)

279-290

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Protein stability modulated by a conformational effector: effects of trifluoroethanol on bovine serum albumin.

15 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Theoretical analysis of Lumry-Eyring models in differential scanning calorimetry

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Antibody therapeutics, antibody engineering, and the merits of protein stability

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Revisiting the method of cumulants for the analysis of dynamic light-scattering data

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Extrinsic fluorescent dyes as tools for protein characterization

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Heterogeneity of monoclonal antibodies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Non-native protein aggregation kinetics

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Effects of protein aggregates: an immunologic perspective

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Antibody structure, instability, and formulation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Structural characterization and immunogenicity in wild-type and immune tolerant mice of degraded recombinant human interferon alpha2b.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Protein drug stability: a formulation challenge

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Protein folding and misfolding

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Physical stability of proteins in aqueous solution: mechanism and driving forces in nonnative protein aggregation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

High-density miniaturized thermal shift assays as a general strategy for drug discovery

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Calculation of hydrodynamic properties of globular proteins from their atomic-level structure

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Approximate Population Balance Equations for Aggregation-Breakage Processes.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

The thermal stability of immunoglobulin: unfolding and aggregation of a multi-domain protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

A transient expansion of the native state precedes aggregation of recombinant human interferon-gamma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Differential scanning calorimetry of proteins.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Characterization of high-molecular-weight nonnative aggregates and aggregation kinetics by size exclusion chromatography with inline multi-angle laser light scattering

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Branching in amyloid fibril growth

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Elucidation of two major aggregation pathways in an IgG2 antibody

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Amyloid-a state in many guises: survival of the fittest fibril fold

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Immunogenicity of protein therapeutics

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Contribution of variable domains to the stability of humanized IgG1 monoclonal antibodies.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

A broad range of Fab stabilities within a host of therapeutic IgGs.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Protein particulates: another generic form of protein aggregation?

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Real-time and single fibril observation of the formation of amyloid beta spherulitic structures

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Solvation-assisted pressure tuning of insulin fibrillation: from novel aggregation pathways to biotechnological applications

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

The kinetic behavior of insulin fibrillation is determined by heterogeneous nucleation pathways

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Active dimer of Epratuzumab provides insight into the complex nature of an antibody aggregate.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Kinetic study on thermal denaturation of hen egg-white lysozyme involving precipitation.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Protofibril formation of amyloid beta-protein at low pH via a non-cooperative elongation mechanism.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

From the bench to the bedside: ways to improve rituximab efficacy.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Characterization and isolation of intermediates in beta-lactoglobulin heat aggregation at high pH.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Lower kinetic limit to protein thermal stability: a proposal regarding protein stability in vivo and its relation with misfolding diseases

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Analysis of protein aggregation kinetics.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Differential scanning calorimetry of the irreversible thermal denaturation of thermolysin

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865720

Universal kinetics in reaction-limited aggregation

29 October 2018

1 reference

12 December 2020

Induction and analysis of aggregates in a liquid IgG1-antibody formulation

1 reference

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Protein structural conformation and not second virial coefficient relates to long-term irreversible aggregation of a monoclonal antibody and ovalbumin in solution

1 reference

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Highly concentrated monoclonal antibody solutions: direct analysis of physical structure and thermal stability

1 reference

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Kinetics of Different Processes in Human Insulin Amyloid Formation

1 reference

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Shaken, not stirred: mechanical stress testing of an IgG1 antibody

1 reference

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Analysis of Aggregate Structure in Food Protein Gels with the Concept of Fractal

1 reference

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Intrinsically stable IgG aggregates

1 reference

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Variable aggregation rates in colloidal gold: Kernel homogeneity dependence on aggregant concentration

1 reference

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Identifiers

DOI

10.1002/PRO.309

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20014440%20AND%20SRC:MED&resulttype=core&format=json

release_pf2x7a53vvfr7fayrkn3jziws4

15 January 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/pf2x7a53vvfr7fayrkn3jziws4

24 November 2022

mapped directly with Wikidata item

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15 January 2020

PubMed publication ID

20014440

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