Trypsin activates pancreatic duct epithelial cell ion channels through proteinase-activated receptor-2. (Q33834687)

29 July 2017

Trypsin activates pancreatic duct epithelial cell ion channels through proteinase-activated receptor-2. (English)

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29 July 2017

T D Nguyen

1

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29 July 2017

M W Moody

2

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29 July 2017

M Steinhoff

3

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29 July 2017

C Okolo

4

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29 July 2017

D S Koh

5

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29 July 2017

N W Bunnett

6

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29 July 2017

language of work or name

English

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publication date

1 January 1999

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Journal of Clinical Investigation

29 July 2017

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29 July 2017

103

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29 July 2017

261-269

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29 July 2017

2

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A dual thrombin receptor system for platelet activation

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Proteinase-activated receptors: novel mechanisms of signaling by serine proteases.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Secretory effects of ATP on nontransformed dog pancreatic duct epithelial cells.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Histamine stimulates ion transport by dog pancreatic duct epithelial cells through H1 receptors.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Proteinase-activated receptor 2 (PAR2)-activating peptides: identification of a receptor distinct from PAR2 that regulates intestinal transport

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Cloning and characterization of human protease-activated receptor 4

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Dual endothelium-dependent vascular activities of proteinase-activated receptor-2-activating peptides: evidence for receptor heterogeneity.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Characterization of protease-activated receptor-2 immunoreactivity in normal human tissues

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Luminal trypsin may regulate enterocytes through proteinase-activated receptor 2.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Protease-activated receptor 3 is a second thrombin receptor in humans

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Interactions of mast cell tryptase with thrombin receptors and PAR-2.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Endocytosis and recycling of neurokinin 1 receptors in enteric neurons

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Dog pancreatic duct epithelial cells: long-term culture and characterization

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Rat proteinase-activated receptor-2 (PAR-2): cDNA sequence and activity of receptor-derived peptides in gastric and vascular tissue

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Mechanisms of desensitization and resensitization of proteinase-activated receptor-2.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. Comparison with the thrombin receptor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Molecular cloning of a potential proteinase activated receptor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Free proteolytic enzymes in pancreatic juice of patients with acute pancreatitis.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

A new generation of Ca2+ indicators with greatly improved fluorescence properties

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

A simple assay for agonist-regulated Cl and K conductances in salt-secreting epithelial cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Modulation of human colonic T84 cell secretion by hydrogen peroxide.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407874

Activation of proteases in cerulein-induced pancreatitis

29 October 2018

1 reference

12 December 2020

Characterization of two distinct chloride channels in cultured dog pancreatic duct epithelial cells

1 reference

12 December 2020

Proteinase-activated receptors: structural requirements for activity, receptor cross-reactivity, and receptor selectivity of receptor-activating peptides

1 reference

12 December 2020

Intra-acinar cell activation of trypsinogen during caerulein-induced pancreatitis in rats

1 reference

12 December 2020

Calcium-activated potassium conductances on cultured nontransformed dog pancreatic duct epithelial cells

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI2539

1 reference

29 July 2017

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29 July 2017

1 reference