Discovery of the antidepressant and anti-emetic efficacy of substance P receptor (NK1) antagonists (Q33835813)

29 July 2017

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title

Discovery of the antidepressant and anti-emetic efficacy of substance P receptor (NK1) antagonists (English)

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29 July 2017

Rupniak NM

1

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PubMed ID

10671176

29 July 2017

Kramer MS

series ordinal

2

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29 July 2017

1 December 1999

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Trends in Pharmacological Sciences

29 July 2017

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29 July 2017

20

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29 July 2017

485-490

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29 July 2017

12

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Distinct mechanism for antidepressant activity by blockade of central substance P receptors

29 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

The tachykinin NK1 receptor. Part II: Distribution and pathophysiological roles

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

A Potent Nonpeptide Antagonist of the Substance P (NK 1 ) Receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Investigation into species variants in tachykinin NK1 receptors by use of the non-peptide antagonist, CP-96,345

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

In vitro and in vivo predictors of the anti-emetic activity of tachykinin NK1 receptor antagonists.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Antinociceptive activity of NK1 receptor antagonists: non-specific effects of racemic RP67580.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Fertilization of Denuded Rabbit Eggs in vitro by Sperm recovered from the Uterus or Vagina

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Effects of substance P on functionally identified units in cat spinal cord

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Experimental immunohistochemical studies on the localization and distribution of substance P in cat primary sensory neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Noxious heating of the skin releases immunoreactive substance P in the substantia gelatinosa of the cat: a study with antibody microprobes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

A comparison of the anatomical distribution of substance P and substance P receptors in the rat central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Substance P-mediated slow excitatory postsynaptic potential elicited in dorsal horn neurons in vivo by noxious stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

A placebo-controlled trial of L-365,260, a CCKB antagonist, in panic disorder

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Immunocytochemical localization of catecholamine synthesizing enzymes and neuropeptides in area postrema and medial nucleus tractus solitarius of rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Enantioselective inhibition of apomorphine-induced emesis in the ferret by the neurokinin1 receptor antagonist CP-99,994

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Tachykinin NK1 receptor antagonists act centrally to inhibit emesis induced by the chemotherapeutic agent cisplatin in ferrets

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

The action of the NK1 tachykinin receptor antagonist, CP 99,994, in antagonizing the acute and delayed emesis induced by cisplatin in the ferret

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Use of an NK1 receptor antagonist to prevent delayed emesis after cisplatin

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Randomized phase II study of the neurokinin 1 receptor antagonist CJ-11,974 in the control of cisplatin-induced emesis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Reduction of cisplatin-induced emesis by a selective neurokinin-1-receptor antagonist. L-754,030 Antiemetic Trials Group.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Substance P afferents have synaptic contacts with dopaminergic neurons in the ventral tegmental area of the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Behavioural and biochemical responses following activation of midbrain dopamine pathways by receptor selective neurokinin agonists.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Modulation of the rat mesolimbic dopamine pathway by neurokinins

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Evidence for a tonic facilitatory influence of substance P on dopamine release in the nucleus accumbens

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Pharmacology of tachykinin receptors on neurones in the ventral tegmental area of rat brain slices

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

CSF of neuroleptic-naive first-episode schizophrenic patients: levels of biogenic amines, substance P, and peptides derived from chromogranin A (GE-25) and secretogranin II (secretoneurin)

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Substance P receptors: Localization by light microscopic autoradiography in rat brain using [3H]SP as the radioligand

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Distribution, morphology and number of monoamine-synthesizing and substance P-containing neurons in the human dorsal raphe nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Effects of microinjections of the neuropeptide substance P in the dorsal periaqueductal gray on the behaviour of rats in the plus-maze test.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Substance P is involved in the sensitization of the acoustic startle response by footshocks in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Central tachykinins: mediators of defence reaction and stress reactions

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Effects of sequential removal of rats from a group cage, and of individual housing of rats, on substance P, cholecystokinin and somatostatin levels in the periaqueductal grey and limbic regions.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Responsiveness of mesolimbic, mesocortical, septal and hippocampal cholecystokinin and substance P neuronal systems to stress, in the male rat

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Reduction of substance P after chronic antidepressants treatment in the striatum, substantia nigra and amygdala of the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

CSF substance P immunoreactivity in affective disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Role of endogenous substance P in stress-induced activation of mesocortical dopamine neurones.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

The substance P (NK1) receptor antagonist (±)-CP-96,345 causes sedation and motor impairment in Swiss albino mice in the black-and-white box behavioral paradigm

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Anxiolytic action of a neurokinin1 receptor antagonist in the social interaction test.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

Evidence that substance P is utilized in medial amygdaloid facilitation of defensive rage behavior in the cat.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

The effect of imipramine and selected drugs on attack elicited by hypothalamic stimulation in the cat

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901396-6

7 January 2021

10.1016/S0165-6147(99)01396-6

Identifiers

DOI

1 reference

29 July 2017

1 reference

PubMed ID

10671176