Inhibition of amyloid precursor protein processing by beta-secretase through site-directed antibodies (Q33836358)

29 July 2017

title

Inhibition of amyloid precursor protein processing by beta-secretase through site-directed antibodies (English)

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29 July 2017

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Michal Arbel

1

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29 July 2017

Iftach Yacoby

series ordinal

2

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29 July 2017

Beka Solomon

series ordinal

3

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29 July 2017

language of work or name

English

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publication date

13 May 2005

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Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

published in

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29 July 2017

volume

102

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29 July 2017

issue

21

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29 July 2017

page(s)

7718-7723

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Alzheimer's disease and immunotherapy

29 July 2017

cites work

1 reference

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The role of the endosomal/lysosomal system in amyloid-beta production and the pathophysiology of Alzheimer's disease: reexamining the spatial paradox from a lysosomal perspective.

4 July 2018

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The cell adhesion protein P-selectin glycoprotein ligand-1 is a substrate for the aspartyl protease BACE1.

4 July 2018

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Secretases as targets for the treatment of Alzheimer's disease: the prospects

4 July 2018

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Beta-secretase (BACE) as a drug target for Alzheimer's disease

4 July 2018

1 reference

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Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology

4 July 2018

1 reference

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Alzheimer's disease: treatments in discovery and development

4 July 2018

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Alzheimer's beta-secretase, beta-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase

4 July 2018

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A portrait of Alzheimer secretases--new features and familiar faces

4 July 2018

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Secretase targets for Alzheimer's disease: identification and therapeutic potential

4 July 2018

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Phosphorylation regulates intracellular trafficking of beta-secretase

4 July 2018

1 reference

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Alzheimer's disease: genes, proteins, and therapy

4 July 2018

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Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

4 July 2018

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Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations

4 July 2018

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Intraneuronal Abeta42 accumulation in human brain.

4 July 2018

1 reference

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Expression of beta-amyloid precursor protein-CD3gamma chimeras to demonstrate the selective generation of amyloid beta(1-40) and amyloid beta(1-42) peptides within secretory and endocytic compartments

4 July 2018

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Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

4 July 2018

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Evidence that production and release of amyloid beta-protein involves the endocytic pathway

4 July 2018

1 reference

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Amyloid beta-peptide is produced by cultured cells during normal metabolism

4 July 2018

1 reference

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Continuous cultures of fused cells secreting antibody of predefined specificity

4 July 2018

1 reference

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Inhibition of Receptor-mediated Endocytosis Demonstrates Generation of Amyloid β-Protein at the Cell Surface

4 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502427102

Demonstration by FRET of BACE interaction with the amyloid precursor protein at the cell surface and in early endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502427102

Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0502427102

Characterization of alpha 2,6-sialyltransferase cleavage by Alzheimer's beta -secretase (BACE1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502427102

Passive amyloid immunotherapy clears amyloid and transiently activates microglia in a transgenic mouse model of amyloid deposition.

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0502427102

Species-specific immune response to immunization with human versus rodent A beta peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502427102

Enhanced release of amyloid beta-protein from codon 670/671 "Swedish" mutant beta-amyloid precursor protein occurs in both secretory and endocytic pathways

21 January 2018

1 reference

12 December 2020

Maturation and endosomal targeting of beta-site amyloid precursor protein-cleaving enzyme. The Alzheimer's disease beta-secretase

1 reference

12 December 2020

The neuronal endosomal-lysosomal system in Alzheimer's disease

1 reference

12 December 2020

Mutagenesis identifies new signals for beta-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Abeta42

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0502427102

1 reference

29 July 2017

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29 July 2017

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