Tlr4: central component of the sole mammalian LPS sensor (Q33840545)

29 July 2017

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title

Tlr4: central component of the sole mammalian LPS sensor (English)

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29 July 2017

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Beutler B

1

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29 July 2017

1 February 2000

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Current Opinion in Immunology

29 July 2017

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29 July 2017

12

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29 July 2017

1

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29 July 2017

20-26

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The immune system evolved to discriminate infectious nonself from noninfectious self

29 July 2017

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Genetic Control of Leucocyte Responses to Endotoxin

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Genetic basis for unresponsiveness to lipopolysaccharide in C57BL/10Cr mice

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The Primary Role of Lymphoreticnlar Cells in the Mediation of Host Responses to Bacterial Endotoxim

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CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein

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A high-resolution map in the chromosomal region surrounding the Lps locus

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Genetic and Physical Mapping of theLpsLocus: Identification of the Toll-4 Receptor as a Candidate Gene in the Critical Region

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7 January 2021

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

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7 January 2021

Establishment of dorsal-ventral polarity in the Drosophila embryo: genetic studies on the role of the Toll gene product.

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7 January 2021

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

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7 January 2021

A conserved signaling pathway: the Drosophila toll-dorsal pathway

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7 January 2021

A family of human receptors structurally related to Drosophila Toll

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7 January 2021

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

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A conserved signal transduction pathway regulating the activity of the rel-like proteins dorsal and NF-kappa B.

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The human toll signaling pathway: divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6)

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7 January 2021

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

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7 January 2021

The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense

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7 January 2021

Analysis of Tlr4-mediated LPS signal transduction in macrophages by mutational modification of the receptor

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7 January 2021

Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

1 reference

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7 January 2021

Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide

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7 January 2021

The toll of innate immunity on microbial pathogens

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Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

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7 January 2021

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

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7 January 2021

Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2

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7 January 2021

Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors

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7 January 2021

Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2

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7 January 2021

Effect of gamma interferon on cachectin expression by mononuclear phagocytes. Reversal of the lpsd (endotoxin resistance) phenotype

1 reference

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7 January 2021

Control of cachectin (tumor necrosis factor) synthesis: mechanisms of endotoxin resistance.

1 reference

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7 January 2021

Adaptation to bacterial lipopolysaccharide controls lipopolysaccharide-induced tumor necrosis factor production in rabbit macrophages

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7 January 2021

Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice

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7 January 2021

Toll, a new piece in the puzzle of innate immunity

1 reference

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7 January 2021

Physical contact between lipopolysaccharide and toll-like receptor 4 revealed by genetic complementation

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7 January 2021

Comparative studies on the toxicity of Escherichia coli lipopolysaccharide endotoxin in various animal species

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7 January 2021

Unresponsiveness of MyD88-deficient mice to endotoxin

1 reference

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7 January 2021

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

1 reference

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7 January 2021

Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium

1 reference

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7 January 2021

10.1016/S0952-7915(99)00046-1

Identifiers

DOI

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29 July 2017

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PubMed ID

10679411