RGS4 is a negative regulator of insulin release from pancreatic beta-cells in vitro and in vivo (Q33842962)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20385802%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

title

RGS4 is a negative regulator of insulin release from pancreatic beta-cells in vitro and in vivo (English)

1 reference

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30 January 2020

2

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30 January 2020

Philip J Ebert

7

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30 January 2020

author name string

Inigo Ruiz de Azua

1

1 reference

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30 January 2020

Erica Rosemond

3

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30 January 2020

Dinesh Gautam

4

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30 January 2020

William Jou

5

1 reference

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30 January 2020

Oksana Gavrilova

6

1 reference

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30 January 2020

Pat Levitt

8

1 reference

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30 January 2020

Jürgen Wess

9

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30 January 2020

language of work or name

English

0 references

publication date

12 April 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20385802%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

30 January 2020

published in

1 reference

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30 January 2020

volume

107

1 reference

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30 January 2020

page(s)

7999-8004

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30 January 2020

issue

17

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RGS4 controls renal blood flow and inhibits cyclosporine-mediated nephrotoxicity.

30 January 2020

cites work

1 reference

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Islet G protein-coupled receptors as potential targets for treatment of type 2 diabetes

28 July 2018

1 reference

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The Gbeta5-RGS7 complex selectively inhibits muscarinic M3 receptor signaling via the interaction between the third intracellular loop of the receptor and the DEP domain of RGS7

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867926

RGS4 regulates parasympathetic signaling and heart rate control in the sinoatrial node

28 July 2018

1 reference

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M3 muscarinic acetylcholine receptor-mediated signaling is regulated by distinct mechanisms

28 July 2018

1 reference

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A role of RGS proteins in drug addiction

28 July 2018

1 reference

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Bacterial artificial chromosome transgenic analysis of dynamic expression patterns of regulator of G-protein signaling 4 during development. I. Cerebral cortex

28 July 2018

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Making the case for a candidate vulnerability gene in schizophrenia: Convergent evidence for regulator of G-protein signaling 4 (RGS4)

28 July 2018

1 reference

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A critical role for beta cell M3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo

28 July 2018

1 reference

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Cellular mechanisms that determine selective RGS protein regulation of G protein-coupled receptor signaling

28 July 2018

1 reference

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Regional expression of RGS4 mRNA in human brain

28 July 2018

1 reference

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The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes

28 July 2018

1 reference

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Cellular regulation of RGS proteins: modulators and integrators of G protein signaling

28 July 2018

1 reference

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Seven-transmembrane receptors

28 July 2018

1 reference

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Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function

28 July 2018

1 reference

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GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins

28 July 2018

1 reference

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Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867926

Molecular biology of muscarinic acetylcholine receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867926

Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867926

Muscarinic stimulation and antagonism and glucoregulation in nondiabetic and obese hyperglycemic mice

28 July 2018

1 reference

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New drug targets for type 2 diabetes and the metabolic syndrome

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003655107

Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003655107

Effects of muscarinic receptor type 3 knockout on mouse islet secretory responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003655107

Location, location, location...site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003655107

Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003655107

R4 RGS proteins: regulation of G-protein signaling and beyond

21 January 2018

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The organization of the transcriptional network in specific neuronal classes.

21 January 2018

1 reference

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RGS proteins have a signalling complex: interactions between RGS proteins and GPCRs, effectors, and auxiliary proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003655107

Bacterial artificial chromosome transgenic analysis of dynamic expression patterns of regulator of G-protein signaling 4 during development. II. Subcortical regions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003655107

RGS4-dependent attenuation of M4 autoreceptor function in striatal cholinergic interneurons following dopamine depletion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003655107

Regulator of G protein signaling-4 controls fatty acid and glucose homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1003655107

Breast cancer migration and invasion depend on proteasome degradation of regulator of G-protein signaling 4.

21 January 2018

1 reference

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Regulators of G-protein signalling as new central nervous system drug targets.

21 January 2018

1 reference

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Differentially Regulated Expression of Endogenous RGS4 and RGS7

21 January 2018

1 reference

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Quantitative real-time polymerase chain reaction measurement of regulators of G-protein signaling mRNA levels in mouse tissues

21 January 2018

1 reference

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Muscarinic stimulation of pancreatic insulin and glucagon release is abolished in m3 muscarinic acetylcholine receptor-deficient mice

29 October 2018

1 reference

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RGS Proteins Determine Signaling Specificity of Gq-coupled Receptors

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20385802

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Multiple residues in the second extracellular loop are critical for M3 muscarinic acetylcholine receptor activation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20385802

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1003655107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20385802%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20385802%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference