PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms. (Q33844610)

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25 January 2020

title

PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms (English)

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25 January 2020

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2

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25 January 2020

author name string

Oliver Mortusewicz

1

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25 January 2020

Jean-Christophe Amé

3

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25 January 2020

Heinrich Leonhardt

4

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25 January 2020

Valérie Schreiber

5

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language of work or name

English

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publication date

11 March 2011

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25 January 2020

published in

Nucleic Acids Research

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25 January 2020

volume

39

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issue

12

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25 January 2020

page(s)

5045-5056

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Creative Commons Attribution-NonCommercial 2.5 Generic

25 January 2020

copyright license

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Dual role of poly(ADP-ribose) glycohydrolase in the regulation of cell death in oxidatively stressed A549 cells

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PCNA on the crossroad of cancer

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A specific isoform of poly(ADP-ribose) glycohydrolase is targeted to the mitochondrial matrix by a N-terminal mitochondrial targeting sequence.

5 July 2018

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Recruitment of RNA polymerase II cofactor PC4 to DNA damage sites

5 July 2018

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PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility

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Functional localization of two poly(ADP-ribose)-degrading enzymes to the mitochondrial matrix

5 July 2018

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Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells

5 July 2018

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XRCC1 and PCNA are loading platforms with distinct kinetic properties and different capacities to respond to multiple DNA lesions

5 July 2018

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Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase

5 July 2018

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PCNA, the maestro of the replication fork

5 July 2018

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Two small enzyme isoforms mediate mammalian mitochondrial poly(ADP-ribose) glycohydrolase (PARG) activity.

5 July 2018

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Recruitment of DNA repair synthesis machinery to sites of DNA damage/repair in living human cells

5 July 2018

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Poly(ADP-ribose) (PAR) polymer is a death signal

5 July 2018

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Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death

5 July 2018

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Spatiotemporal dynamics of p21CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen

5 July 2018

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Dynamic relocation of poly(ADP-ribose) glycohydrolase isoforms during radiation-induced DNA damage

5 July 2018

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Recruitment of DNA methyltransferase I to DNA repair sites

5 July 2018

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Identification of three critical acidic residues of poly(ADP-ribose) glycohydrolase involved in catalysis: determining the PARG catalytic domain

5 July 2018

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Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality

5 July 2018

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In situ analysis of repair processes for oxidative DNA damage in mammalian cells.

5 July 2018

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Depletion of the 110-kilodalton isoform of poly(ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice

5 July 2018

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Human poly(ADP-ribose) glycohydrolase is expressed in alternative splice variants yielding isoforms that localize to different cell compartments

5 July 2018

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A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage

5 July 2018

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ATP-dependent selection between single nucleotide and long patch base excision repair.

5 July 2018

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5 July 2018

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PCNA clamp facilitates action of DNA cytosine methyltransferase 1 on hemimethylated DNA

5 July 2018

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PCNA binding through a conserved motif

5 July 2018

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Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structure

5 July 2018

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The macroPARP genes Parp-9 and Parp-14 are developmentally and differentially regulated in mouse tissues.

5 July 2018

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Radiation-induced mitotic catastrophe in PARG-deficient cells.

21 January 2018

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Detection of the nuclear poly(ADP-ribose)-metabolizing enzymes and activities in response to DNA damage.

21 January 2018

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DNA polymerase beta -mediated long patch base excision repair. Poly(ADP-ribose)polymerase-1 stimulates strand displacement DNA synthesis.

21 January 2018

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MNNG-induced cell death is controlled by interactions between PARP-1, poly(ADP-ribose) glycohydrolase, and XRCC1.

21 January 2018

1 reference

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Proliferating Cell Nuclear Antigen Facilitates Excision in Long-patch Base Excision Repair

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1093/NAR/GKR099

1 reference

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25 January 2020

1 reference

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25 January 2020

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