Rhabdoid tumor: gene expression clues to pathogenesis and potential therapeutic targets (Q33844721)

29 July 2017

Rhabdoid tumor: gene expression clues to pathogenesis and potential therapeutic targets (English)

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29 July 2017

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Samantha Gadd

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29 July 2017

Simone Treiger Sredni

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29 July 2017

Chiang-Ching Huang

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29 July 2017

Elizabeth J Perlman

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29 July 2017

Renal Tumor Committee of the Children's Oncology Group

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29 July 2017

8 March 2010

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29 July 2017

Laboratory Investigation

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29 July 2017

90

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29 July 2017

5

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29 July 2017

724-738

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https://scigraph.springernature.com/pub.10.1038/labinvest.2010.66

29 July 2017

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cites work

Differential expression profiling between atypical teratoid/rhabdoid and medulloblastoma tumor in vitro and in vivo using microarray analysis

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The ZNF217 oncogene is a candidate organizer of repressive histone modifiers

5 July 2018

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The role of INI1/hSNF5 in gene regulation and cancer

5 July 2018

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Imprinted CDKN1C is a tumor suppressor in rhabdoid tumor and activated by restoration of SMARCB1 and histone deacetylase inhibitors

5 July 2018

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Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells

5 July 2018

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Atlas of gene expression in the developing kidney at microanatomic resolution

5 July 2018

1 reference

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Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin signaling

5 July 2018

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Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells

5 July 2018

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SWI/SNF mediates polycomb eviction and epigenetic reprogramming of the INK4b-ARF-INK4a locus

5 July 2018

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The requirement for SNF5/INI1 in adipocyte differentiation highlights new features of malignant rhabdoid tumors

5 July 2018

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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

5 July 2018

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Polycomb silencers control cell fate, development and cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

The tumour suppressor hSNF5/INI1 controls the differentiation potential of malignant rhabdoid cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Osteopontin knockdown suppresses tumorigenicity of human metastatic breast carcinoma, MDA-MB-435

5 July 2018

1 reference

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Polycomb complexes repress developmental regulators in murine embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

The c-myc gene is a direct target of mammalian SWI/SNF-related complexes during differentiation-associated cell cycle arrest

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Classification of malignant pediatric renal tumors by gene expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Clear cell sarcoma of the kidney: up-regulation of neural markers with activation of the sonic hedgehog and Akt pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Loss of the hSNF5 gene concomitantly inactivates p21CIP/WAF1 and p16INK4a activity associated with replicative senescence in A204 rhabdoid tumor cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Oncogenic pathway signatures in human cancers as a guide to targeted therapies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Receptor-type protein-tyrosine phosphatase-kappa regulates epidermal growth factor receptor function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

The SWI/SNF chromatin-remodeling complex subunit SNF5 is essential for hepatocyte differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Genetic ablation of Cyclin D1 abrogates genesis of rhabdoid tumors resulting from Ini1 loss

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Sox proteins and neural crest development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Early steps in neural crest specification.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Endostatin: the logic of antiangiogenic therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Galectin-1 as a potential cancer target

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Increased expression of osteopontin gene in atypical teratoid/rhabdoid tumor of the central nervous system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Xenopus Id3 is required downstream of Myc for the formation of multipotent neural crest progenitor cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Expression and characterization of recombinant osteopontin peptides representing matrix metalloproteinase proteolytic fragments

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Nestin expression--a property of multi-lineage progenitor cells?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Imprinting along the Kcnq1 domain on mouse chromosome 7 involves repressive histone methylation and recruitment of Polycomb group complexes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

The tumor suppressor hSNF5/INI1 modulates cell growth and actin cytoskeleton organization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

The SWI/SNF complex--chromatin and cancer.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

P16INK4a is required for hSNF5 chromatin remodeler-induced cellular senescence in malignant rhabdoid tumor cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

PANTHER: a library of protein families and subfamilies indexed by function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

SOX10 Maintains Multipotency and Inhibits Neuronal Differentiation of Neural Crest Stem Cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Recent advances in understanding chromatin remodeling by Swi/Snf complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

DOCK4, a GTPase activator, is disrupted during tumorigenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

MLL targets SET domain methyltransferase activity to Hox gene promoters

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Prediction of central nervous system embryonal tumour outcome based on gene expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

The role of INI1 and the SWI/SNF complex in the development of rhabdoid tumors: meeting summary from the workshop on childhood atypical teratoid/rhabdoid tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Function of the c-Myc oncoprotein in chromatin remodeling and transcription.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

The transcriptional program of a human B cell line in response to Myc

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Detection of the ETV6-NTRK3 chimeric RNA of infantile fibrosarcoma/cellular congenital mesoblastic nephroma in paraffin-embedded tissue: application to challenging pediatric renal stromal tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Atypical teratoid/rhabdoid tumor of the central nervous system: a highly malignant tumor of infancy and childhood frequently mistaken for medulloblastoma: a Pediatric Oncology Group study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Central nervous system atypical teratoid/rhabdoid tumors of infancy and childhood

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Repression of cyclin D1: a novel function of MYC

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Rhabdoid tumor of the kidney in the National Wilms' Tumor Study: age at diagnosis as a prognostic factor.

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.66

INI1 induces interferon signaling and spindle checkpoint in rhabdoid tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.66

Re-expression of hSNF5/INI1/BAF47 in pediatric tumor cells leads to G1 arrest associated with induction of p16ink4a and activation of RB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.66

Role of DNA methylation and histone H3 lysine 27 methylation in tissue-specific imprinting of mouse Grb10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.66

A novel model for an older remodeler: the BAF swap in neurogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.66

HB-GAM inhibits proliferation and enhances differentiation of neural stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.66

The basic helix-loop-helix genes Hesr1/Hey1 and Hesr2/Hey2 regulate maintenance of neural precursor cells in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.66

Snail precedes slug in the genetic cascade required for the specification and migration of the Xenopus neural crest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.66

Isolation and characterization of murine neural stem/progenitor cells based on Prominin-1 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.66

Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.66

The protooncogene c-myc is an essential regulator of neural crest formation in xenopus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.66

Targeting cyclin D1, a downstream effector of INI1/hSNF5, in rhabdoid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.66

Pigment epithelium-derived factor is a niche signal for neural stem cell renewal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.66

Alterations of the hSNF5/INI1 gene in central nervous system atypical teratoid/rhabdoid tumors and renal and extrarenal rhabdoid tumors

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868345

Immunohistochemical analysis of hSNF5/INI1 distinguishes renal and extra-renal malignant rhabdoid tumors from other pediatric soft tissue tumors

29 October 2018

1 reference

12 December 2020

Phase I study of recombinant human endostatin in patients with advanced solid tumors

1 reference

12 December 2020

Snf5 tumor suppressor couples chromatin remodeling, checkpoint control, and chromosomal stability

1 reference

12 December 2020

Inhibition of a protein-protein interaction between INI1 and c-Myc by small peptidomimetic molecules inspired by Helix-1 of c-Myc: identification of a new target of potential antineoplastic interest

1 reference

12 December 2020

Osteopontin as a molecular prognostic marker for melanoma

1 reference

12 December 2020

10.1038/LABINVEST.2010.66

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DOI

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Dimensions Publication ID

29 July 2017

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1 reference

29 July 2017

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