Inside-out regulation of L1 conformation, integrin binding, proteolysis, and concomitant cell migration. (Q33848745)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20335502%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Inside-out regulation of L1 conformation, integrin binding, proteolysis, and concomitant cell migration (English)

1 reference

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29 January 2020

1 reference

1

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29 January 2020

Hyuma Leland

3

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29 January 2020

author name string

Chia-Yao Lee

2

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29 January 2020

Grace Y Lin

4

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29 January 2020

Anthony M Montgomery

5

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29 January 2020

Steve Silletti

6

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29 January 2020

publication date

24 March 2010

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Molecular Biology of the Cell

29 January 2020

published in

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29 January 2020

volume

21

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29 January 2020

issue

10

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29 January 2020

page(s)

1671-1685

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Tyrosine and serine phosphorylation regulate the conformation and subsequent threonine phosphorylation of the L1 cytoplasmic domain.

29 January 2020

cites work

1 reference

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Characterization of the neuron-specific L1-CAM cytoplasmic tail: naturally disordered in solution it exercises different binding modes for different adaptor proteins

5 July 2018

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The cytoplasmic part of L1-CAM controls growth and gene expression in human tumors that is reversed by therapeutic antibodies

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44

5 July 2018

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RanBPM is an L1-interacting protein that regulates L1-mediated mitogen-activated protein kinase activation

5 July 2018

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L1, a novel target of beta-catenin signaling, transforms cells and is expressed at the invasive front of colon cancers

5 July 2018

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Extracellular signal-regulated kinase (ERK)-dependent gene expression contributes to L1 cell adhesion molecule-dependent motility and invasion

5 July 2018

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The L1CAM extracellular region: a multi-domain protein with modular and cooperative binding modes

5 July 2018

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5 July 2018

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L1 endocytosis is controlled by a phosphorylation-dephosphorylation cycle stimulated by outside-in signaling by L1.

5 July 2018

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The neural cell adhesion molecule L1 potentiates integrin-dependent cell migration to extracellular matrix proteins.

5 July 2018

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Functional binding interaction identified between the axonal CAM L1 and members of the ERM family

5 July 2018

1 reference

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Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins

5 July 2018

1 reference

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Alternative use of a mini exon of the L1 gene affects L1 binding to neural ligands

5 July 2018

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Cell adhesion molecule L1 in folded (horseshoe) and extended conformations

5 July 2018

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L-plastin peptide activation of alpha(v)beta(3)-mediated adhesion requires integrin conformational change and actin filament disassembly

5 July 2018

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Factors influencing survival after resection for periampullary neoplasms

5 July 2018

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Plasmin-sensitive dibasic sequences in the third fibronectin-like domain of L1-cell adhesion molecule (CAM) facilitate homomultimerization and concomitant integrin recruitment

5 July 2018

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The third fibronectin type III repeat is required for L1 to serve as an optimal substratum for neurite extension

5 July 2018

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The crystal structure of the ligand binding module of axonin-1/TAG-1 suggests a zipper mechanism for neural cell adhesion

5 July 2018

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Critical and optimal Ig domains for promotion of neurite outgrowth by L1/Ng-CAM.

5 July 2018

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Activation of alphaVbeta3 on vascular cells controls recognition of prothrombin

5 July 2018

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5 July 2018

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Structural requirements for outside-in and inside-out signaling by Drosophila neuroglian, a member of the L1 family of cell adhesion molecules

5 July 2018

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A neuronal form of the cell adhesion molecule L1 contains a tyrosine-based signal required for sorting to the axonal growth cone.

5 July 2018

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5 July 2018

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A single immunoglobulin-like domain of the human neural cell adhesion molecule L1 supports adhesion by multiple vascular and platelet integrins

5 July 2018

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5 July 2018

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Mutational analysis of the L1 neuronal cell adhesion molecule identifies membrane-proximal amino acids of the cytoplasmic domain that are required for cytoskeletal anchorage

5 July 2018

1 reference

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Implications for the domain arrangement of axonin-1 derived from the mapping of its NgCAM binding site

5 July 2018

1 reference

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Casein kinase II phosphorylates the neural cell adhesion molecule L1.

5 July 2018

1 reference

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CRASH syndrome: clinical spectrum of corpus callosum hypoplasia, retardation, adducted thumbs, spastic paraparesis and hydrocephalus due to mutations in one single gene, L1.

5 July 2018

1 reference

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Colocalization of the homophilic binding site and the neuritogenic activity of the cell adhesion molecule L1 to its second Ig-like domain

5 July 2018

1 reference

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Characterization of a unique glycoprotein antigen expressed on the surface of human neuroblastoma cells.

5 July 2018

1 reference

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The 200/220 kDa antigen recognized by monoclonal antibody (MAb) UJ127.11 on neural tissues and tumors is the human L1 adhesion molecule.

5 July 2018

1 reference

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Molecular structure and functional testing of human L1CAM: an interspecies comparison

5 July 2018

1 reference

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L1 expression as a predictor of progression and survival in patients with uterine and ovarian carcinomas.

5 July 2018

1 reference

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MT1-MMP initiates activation of pro-MMP-2 and integrin alphavbeta3 promotes maturation of MMP-2 in breast carcinoma cells

29 October 2018

1 reference

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A potential role for the plasmin(ogen) system in the posttranslational cleavage of the neural cell adhesion molecule L1.

29 October 2018

1 reference

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The role of cell adhesion molecule L1 in axonal extension, growth cone motility, and signal transduction

29 October 2018

1 reference

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Disulfide-mediated dimerization of L1 Ig domains

29 October 2018

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12 December 2020

Overexpression of the cell adhesion molecule L1 is associated with metastasis in cutaneous malignant melanoma

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12 December 2020

L1 adhesion molecule (CD 171) in development and progression of human malignant melanoma

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12 December 2020

Several extracellular domains of the neural cell adhesion molecule L1 are involved in homophilic interactions

1 reference

12 December 2020

Metalloproteinase-mediated release of the ectodomain of L1 adhesion molecule

1 reference

12 December 2020

Absence of L1 in pancreatic masses distinguishes adenocarcinomas from poorly differentiated neuroendocrine carcinomas

1 reference

12 December 2020

The role of cytoplasmic serine residues of the cell adhesion molecule L1 in neurite outgrowth, endocytosis, and cell migration

1 reference

12 December 2020

Role of Src kinases in the ADAM-mediated release of L1 adhesion molecule from human tumor cells

1 reference

12 December 2020

Trimerization of cell adhesion molecule L1 mimics clustered L1 expression on the cell surface: influence on L1-ligand interactions and on promotion of neurite outgrowth

1 reference

12 December 2020

Structural analysis of the murine cell adhesion molecule L1 by electron microscopy and computer-assisted modelling

1 reference

12 December 2020

L1 (CAM) (CD171) in ovarian serous neoplasms

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12 December 2020

Identifiers

DOI

10.1091/MBC.E09-10-0900

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20335502%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20335502%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference