Identification of human ABAD inhibitors for rescuing Aβ-mediated mitochondrial dysfunction (Q33850211)

29 July 2017

title

Identification of human ABAD inhibitors for rescuing Aβ-mediated mitochondrial dysfunction (English)

1 reference

29 July 2017

author name string

Koteswara R Valaasani

1

1 reference

29 July 2017

Qinru Sun

2

1 reference

29 July 2017

Gang Hu

3

1 reference

29 July 2017

Jianping Li

4

1 reference

29 July 2017

Fang Du

5

1 reference

29 July 2017

Yaopeng Guo

6

1 reference

29 July 2017

Emily A Carlson

7

1 reference

29 July 2017

Xueqi Gan

8

1 reference

29 July 2017

Shirley S Yan

9

1 reference

29 July 2017

publication date

1 February 2014

1 reference

Current Alzheimer Research

29 July 2017

published in

1 reference

29 July 2017

volume

11

1 reference

29 July 2017

issue

2

1 reference

29 July 2017

page(s)

128-136

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Mitochondrial permeability transition pore is a potential drug target for neurodegeneration

29 July 2017

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model

28 July 2018

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Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

28 July 2018

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Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Binding of amyloid beta-peptide to mitochondrial hydroxyacyl-CoA dehydrogenase (ERAB): regulation of an SDR enzyme activity with implications for apoptosis in Alzheimer's disease

28 July 2018

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Synthesis and in vitro properties of a powerful quaternary methylphosphonate inhibitor of acetylcholinesterase. A new marker in blood-brain barrier research

28 July 2018

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Multipotent, permeable drug ASS234 inhibits Aβ aggregation, possesses antioxidant properties and protects from Aβ-induced apoptosis in vitro

28 July 2018

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A longitudinal FDG-PET study of transgenic mice overexpressing GSK- 3β in the brain

29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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Structure-based design and synthesis of benzothiazole phosphonate analogues with inhibitors of human ABAD-Aβ for treatment of Alzheimer's disease

29 October 2018

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29 October 2018

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Synthesis, spectral characterization and biological evaluation of phosphorylated derivatives of galanthamine

29 October 2018

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Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice

29 October 2018

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29 October 2018

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Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease

29 October 2018

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Mitochondrial dysfunction and Alzheimer's disease: role of amyloid-beta peptide alcohol dehydrogenase (ABAD).

29 October 2018

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ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4082996

Crystal structure of human ABAD/HSD10 with a bound inhibitor: implications for design of Alzheimer's disease therapeutics.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4082996

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4082996

Role of ERAB/L-3-hydroxyacyl-coenzyme A dehydrogenase type II activity in Abeta-induced cytotoxicity

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4082996

An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4082996

Identification of amyloid-beta binding sites using an antisense peptide approach

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24479630

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identification of small-molecule inhibitors of the Abeta-ABAD interaction

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24479630

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

2-(N-Benzyl-N-phenylsulfonamido)alkyl amide derivatives as γ-secretase inhibitors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24479630

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2174/1567205011666140130150108

1 reference

29 July 2017

1 reference

29 July 2017

1 reference