BET and HDAC inhibitors induce similar genes and biological effects and synergize to kill in Myc-induced murine lymphoma (Q33853887)

29 July 2017

BET and HDAC inhibitors induce similar genes and biological effects and synergize to kill in Myc-induced murine lymphoma (English)

1 reference

29 July 2017

Joydeep Bhadury

1

0 references

author name string

Lisa M Nilsson

2

1 reference

29 July 2017

Somsundar Veppil Muralidharan

3

1 reference

29 July 2017

Lydia C Green

4

1 reference

29 July 2017

Zhoulei Li

5

1 reference

29 July 2017

Emily M Gesner

6

1 reference

29 July 2017

Henrik C Hansen

7

1 reference

29 July 2017

Ulrich B Keller

8

1 reference

29 July 2017

Kevin G McLure

9

1 reference

29 July 2017

Jonas A Nilsson

10

1 reference

29 July 2017

language of work or name

English

0 references

publication date

16 June 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

1 reference

29 July 2017

111

1 reference

29 July 2017

E2721-30

1 reference

29 July 2017

26

1 reference

describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4084424/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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P-TEFb as a target to reactivate latent HIV: two Brds are now in hand

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Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity

5 July 2018

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BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism.

5 July 2018

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Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia AML.

5 July 2018

1 reference

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Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins

5 July 2018

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5 July 2018

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5 July 2018

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BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia

5 July 2018

1 reference

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5 July 2018

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5 July 2018

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Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Efficacy and safety of a novel oral inducer of apolipoprotein a-I synthesis in statin-treated patients with stable coronary artery disease a randomized controlled trial

5 July 2018

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Egr1 mediates p53-independent c-Myc-induced apoptosis via a noncanonical ARF-dependent transcriptional mechanism

5 July 2018

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5 July 2018

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CDK8 is a positive regulator of transcriptional elongation within the serum response network

5 July 2018

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5 July 2018

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Control of inducible gene expression by signal-dependent transcriptional elongation

5 July 2018

1 reference

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The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy

5 July 2018

1 reference

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Myc sensitizes p53-deficient cancer cells to the DNA-damaging effects of the DNA methyltransferase inhibitor decitabine

5 July 2018

1 reference

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Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control

5 July 2018

1 reference

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Genome-wide transcriptional response to 5-aza-2'-deoxycytidine and trichostatin a in multiple myeloma cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084424

Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084424

Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084424

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084424

Early growth response 1 acts as a tumor suppressor in vivo and in vitro via regulation of p53

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084424

Burkitt lymphoma in the mouse.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084424

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084424

INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084424

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084424

Tumor suppressor p53 can participate in transcriptional induction of the GADD45 promoter in the absence of direct DNA binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084424

Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084424

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

5 July 2018

2 references

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1406722111

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/24979794

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1406722111

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference