IL-12-induced IFN-gamma is dependent on caspase-1 processing of the IL-18 precursor (Q33853915)

29 July 2017

IL-12-induced IFN-gamma is dependent on caspase-1 processing of the IL-18 precursor (English)

1 reference

29 July 2017

G Fantuzzi

1

1 reference

29 July 2017

D A Reed

series ordinal

2

1 reference

29 July 2017

C A Dinarello

series ordinal

3

1 reference

29 July 2017

language of work or name

English

0 references

publication date

1 September 1999

1 reference

Journal of Clinical Investigation

29 July 2017

1 reference

29 July 2017

104

1 reference

29 July 2017

6

1 reference

29 July 2017

761-767

1 reference

Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cells

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

IL-18 up-regulates perforin-mediated NK activity without increasing perforin messenger RNA expression by binding to constitutively expressed IL-18 receptor.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

Interleukin 18 contributes to host resistance and gamma interferon production in mice infected with virulent Salmonella typhimurium

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

Overview of interleukin-18: more than an interferon-gamma inducing factor.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

IL-12 and IL-18 differentially regulate the transcriptional activity of the human IFN-gamma promoter in primary CD4+ T lymphocytes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

IL-18 (IFN-gamma-inducing factor) regulates early cytokine production in, and promotes resolution of, bacterial infection in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

Regulation of IL-18 (IFN-gamma-inducing factor) gene expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

Defective NK cell activity and Th1 response in IL-18-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

Immunoregulation by interleukin-12.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

Mechanism of interleukin 12-mediated toxicities during experimental viral infections: role of tumor necrosis factor and glucocorticoids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

Role of interferon-gamma in interleukin 12-induced pathology in mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

Cloning of a new cytokine that induces IFN-gamma production by T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

IL-1 beta is secreted by activated murine macrophages as biologically inactive precursor.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

Interleukin-12 induces sustained activation of multiple host inflammatory mediator systems in chimpanzees.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408443

Inactivation of interleukin-1 beta converting enzyme by peptide (acyloxy)methyl ketones

29 October 2018

1 reference

12 December 2020

Inhibition of mature IL-1 beta production in murine macrophages and a murine model of inflammation by WIN 67694, an inhibitor of IL-1 beta converting enzyme

1 reference

12 December 2020

A new non-isotopic detection system for immunoassays

1 reference

12 December 2020

IL-12 deaths: explanation and a puzzle

1 reference

12 December 2020

A newly defined interleukin-1?

1 reference

12 December 2020

Response to local inflammation of IL-1 beta-converting enzyme- deficient mice

1 reference

12 December 2020

Formation of active IL-1 beta from pro-IL-1 beta catalyzed by stratum corneum chymotryptic enzyme in vitro

1 reference

12 December 2020

Physiological and cytokine responses in IL-1 beta-deficient mice after zymosan-induced inflammation

1 reference

12 December 2020

A mechanism underlying synergy between IL-12 and IFN-gamma-inducing factor in enhanced production of IFN-gamma

1 reference

12 December 2020

Protective effect of a single interleukin-12 (IL-12) predose against the toxicity of subsequent chronic IL-12 in mice: role of cytokines and glucocorticoids

1 reference

12 December 2020

Interleukin-18 regulation of interferon gamma production and cell proliferation as shown in interleukin-1beta-converting enzyme (caspase-1)-deficient mice

1 reference

12 December 2020

IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production

1 reference

12 December 2020

Expression of interleukin-18 in murine contact hypersensitivity

1 reference

12 December 2020

Interleukin‐18 Enhances Lipopolysaccharide‐Induced Interferon‐γ Production in Human Whole Blood Cultures

1 reference

12 December 2020

Regulation of human IL-18 mRNA expression

1 reference

12 December 2020

IL-18 is produced by articular chondrocytes and induces proinflammatory and catabolic responses

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI7501

1 reference

29 July 2017

1 reference

29 July 2017

1 reference