C --> T mutagenesis and gamma-radiation sensitivity due to deficiency in the Smug1 and Ung DNA glycosylases (Q33854159)

29 July 2017

title

C --> T mutagenesis and gamma-radiation sensitivity due to deficiency in the Smug1 and Ung DNA glycosylases (English)

1 reference

29 July 2017

3

Tomas Lindahl

1 reference

29 July 2017

Qian An

1

1 reference

29 July 2017

Peter Robins

series ordinal

2

1 reference

29 July 2017

Deborah E Barnes

series ordinal

4

1 reference

29 July 2017

language of work or name

English

0 references

publication date

19 May 2005

1 reference

29 July 2017

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29 July 2017

volume

24

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29 July 2017

issue

12

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29 July 2017

page(s)

2205-2213

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Repair and genetic consequences of endogenous DNA base damage in mammalian cells

29 July 2017

cites work

1 reference

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Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation

5 July 2018

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Mutational analysis of the damage-recognition and catalytic mechanism of human SMUG1 DNA glycosylase

5 July 2018

1 reference

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Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming

5 July 2018

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Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase

5 July 2018

1 reference

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Escherichia coli nucleoside diphosphate kinase does not act as a uracil-processing DNA repair nuclease

5 July 2018

1 reference

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Differential specificity of human and Escherichia coli endonuclease III and VIII homologues for oxidative base lesions

5 July 2018

1 reference

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The transcription factor, NFI/CTF plays a positive regulatory role in expression of the hSMUG1 gene

5 July 2018

1 reference

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Substrate specificities and excision kinetics of DNA glycosylases involved in base-excision repair of oxidative DNA damage

5 July 2018

1 reference

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Mutagenicity, toxicity and repair of DNA base damage induced by oxidation

5 July 2018

1 reference

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Immunity through DNA deamination

5 July 2018

1 reference

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Structure and specificity of the vertebrate anti-mutator uracil-DNA glycosylase SMUG1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

Mammalian 5-Formyluracil−DNA Glycosylase. 2. Role of SMUG1 Uracil−DNA Glycosylase in Repair of 5-Formyluracil and Other Oxidized and Deaminated Base Lesions

5 July 2018

1 reference

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Mammalian 5-formyluracil-DNA glycosylase. 1. Identification and characterization of a novel activity that releases 5-formyluracil from DNA

5 July 2018

1 reference

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Repair of the mutagenic DNA oxidation product, 5-formyluracil

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells.

5 July 2018

1 reference

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Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

Unique misinsertion specificity of poliota may decrease the mutagenic potential of deaminated cytosines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

Definitive identification of mammalian 5-hydroxymethyluracil DNA N-glycosylase activity as SMUG1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

Excision of deaminated cytosine from the vertebrate genome: role of the SMUG1 uracil-DNA glycosylase

5 July 2018

1 reference

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The alpha/beta fold uracil DNA glycosylases: a common origin with diverse fates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

Post-replicative base excision repair in replication foci

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

Oxidized, deaminated cytosines are a source of C --> T transitions in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

Novel activities of human uracil DNA N-glycosylase for cytosine-derived products of oxidative DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

Instability and decay of the primary structure of DNA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

A novel activity of E. coli uracil DNA N-glycosylase excision of isodialuric acid (5,6-dihydroxyuracil), a major product of oxidative DNA damage, from DNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

Specific mutator effects of ung (uracil-DNA glycosylase) mutations in Escherichia coli.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

Thymine lesions produced by ionizing radiation in double-stranded DNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

The spectrum of spontaneous mutations in a Saccharomyces cerevisiae uracil-DNA-glycosylase mutant limits the function of this enzyme to cytosine deamination repair

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

A mammalian cell line deficient in activity of the DNA repair enzyme 5-hydroxymethyluracil-DNA glycosylase is resistant to the toxic effects of the thymidine analog 5-hydroxymethyl-2'-deoxyuridine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

Germline transmission of RNAi in mice

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600689

Proteolytic degradation of the nuclear isoform of uracil-DNA glycosylase occurs during the S phase of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600689

Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600689

Oxidation of thymine to 5-formyluracil in DNA promotes misincorporation of dGMP and subsequent elongation of a mismatched primer terminus by DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600689

Mutation frequencies and AID activation state in B-cell lymphomas from Ung-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600689

Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600689

Effects on sister chromatid exchange frequency of aldehyde dehydrogenase 2 genotype and smoking in vinyl chloride workers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600689

Proliferation-dependent expression of nuclear uracil-DNA glycosylase is mediated in part by E2F-4.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

The novel DNA glycosylase, NEIL1, protects mammalian cells from radiation-mediated cell death

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

Relative sensitivity of the endogenous hprt gene and lacl transgene in ENU‐treated big blue™ B6C3F1 mice

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150883

Properties of a Recombinant Human Uracil-DNA Glycosylase from the UNG Gene and Evidence that UNG Encodes the Major Uracil-DNA Glycosylase

29 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600689

Amplification and direct nucleotide sequencing of cDNA from the lysate of low numbers of diploid human cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15902269

12 December 2020

inferred from PubMed ID database lookup

Kinetics of the uracil-DNA glycosylase/inhibitor protein association. Ung interaction with Ugi, nucleic acids, and uracil compounds

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15902269

12 December 2020

inferred from PubMed ID database lookup

Mutagenicity and repair of oxidative DNA damage: insights from studies using defined lesions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15902269

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/SJ.EMBOJ.7600689

1 reference

release_3xwiksrq4nh75o7ujihj6mfxly

29 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/3xwiksrq4nh75o7ujihj6mfxly

24 November 2022

mapped directly with Wikidata item

PMC publication ID

1150883

1 reference

29 July 2017

1 reference